SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1reg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 1reg T4 REGA
(Escherichia
virus
T4) 		4 / 8 PHE X  12
ILE X  86
ILE X   4
LYS X   1
 None
 0.86A 1sbrA-1regX:
undetectable		 1sbrA-1regX:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 1reg T4 REGA
(Escherichia
virus
T4) 		4 / 8 LEU X   6
ILE X  38
ILE X  84
ILE X  47
 None
 0.79A 2bu8A-1regX:
undetectable		 2bu8A-1regX:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 1reg T4 REGA
(Escherichia
virus
T4) 		3 / 3 ASN X  27
ALA X  25
ARG X 102
 None
 0.84A 3tj7C-1regX:
undetectable
3tj7D-1regX:
undetectable		 3tj7C-1regX:
21.13
3tj7D-1regX:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1reg T4 REGA
(Escherichia
virus
T4) 		3 / 3 ARG X  70
ASP X  72
ARG X  71
 None
 0.64A 4wq4B-1regX:
undetectable		 4wq4B-1regX:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1reg T4 REGA
(Escherichia
virus
T4) 		3 / 3 PHE X  93
ASP X  96
LEU X  78
 None
 0.81A 5uhbC-1regX:
undetectable		 5uhbC-1regX:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 1reg T4 REGA
(Escherichia
virus
T4) 		5 / 12 LYS X 117
CYH X  36
ARG X  71
ILE X  74
ASP X  72
 None
 1.16A 6bxmA-1regX:
undetectable		 6bxmA-1regX:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 1reg T4 REGA
(Escherichia
virus
T4) 		5 / 12 LYS X 117
CYH X  36
ARG X  71
ILE X  74
ASP X  72
 None
 1.24A 6bxnA-1regX:
undetectable		 6bxnA-1regX:
16.51