SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rfv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		5 / 10 VAL A  80
ILE A  10
LEU A  91
LYS A 139
VAL A 140
 None
 1.15A 1cqpA-1rfvA:
undetectable
1cqpB-1rfvA:
3.6		 1cqpA-1rfvA:
22.45
1cqpB-1rfvA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		4 / 8 ALA A 228
LEU A 289
ALA A 274
LYS A 275
 None
 0.70A 1e7cA-1rfvA:
3.8		 1e7cA-1rfvA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		4 / 6 GLU A  61
LEU A  62
VAL A  94
MET A  93
 None
 0.96A 1hk1A-1rfvA:
4.2		 1hk1A-1rfvA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		4 / 7 GLU A  61
LEU A  62
VAL A  94
MET A  93
 None
 0.94A 1hk2A-1rfvA:
4.0		 1hk2A-1rfvA:
19.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD2_A_PXLA288_1
(PYRIDOXAMINE KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		6 / 10 SER A  12
VAL A  14
HIS A  46
THR A  47
VAL A 231
ASP A 235
 None
 0.50A 1td2A-1rfvA:
37.3		 1td2A-1rfvA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD2_B_PXLB289_1
(PYRIDOXAMINE KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		5 / 9 HIS A  46
THR A  47
VAL A 115
VAL A 231
ASP A 235
 None
None
ZN  A 402 ( 4.6A)
None
None
 0.72A 1td2B-1rfvA:
37.4		 1td2B-1rfvA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD2_B_PXLB289_1
(PYRIDOXAMINE KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		5 / 9 HIS A  46
TYR A  84
VAL A 115
VAL A 231
ASP A 235
 None
None
ZN  A 402 ( 4.6A)
None
None
 0.81A 1td2B-1rfvA:
37.4		 1td2B-1rfvA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD2_B_PXLB289_1
(PYRIDOXAMINE KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		5 / 9 SER A  12
HIS A  46
THR A  47
VAL A 231
ASP A 235
 None
 0.43A 1td2B-1rfvA:
37.4		 1td2B-1rfvA:
32.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		3 / 3 MET A 221
ASN A 251
GLN A 205
 None
 0.94A 1xoqB-1rfvA:
undetectable		 1xoqB-1rfvA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		4 / 8 SER A  12
VAL A  14
VAL A  19
ASP A 235
 None
 0.51A 2ddwA-1rfvA:
30.6		 2ddwA-1rfvA:
29.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		3 / 3 LEU A  28
PRO A  27
LEU A  31
 None
 0.56A 2po5B-1rfvA:
2.2		 2po5B-1rfvA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		4 / 6 LEU A 132
VAL A 135
VAL A  94
VAL A  95
 None
 0.99A 2z97A-1rfvA:
undetectable		 2z97A-1rfvA:
24.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHX_A_PXLA313_1
(PYRIDOXAL KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		4 / 4 SER A  12
HIS A  46
THR A  47
VAL A 231
 None
 0.71A 3fhxA-1rfvA:
48.2		 3fhxA-1rfvA:
86.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		5 / 8 SER A  12
PHE A  43
HIS A  46
THR A  47
VAL A 231
 None
 0.75A 3fhxB-1rfvA:
47.7		 3fhxB-1rfvA:
86.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		6 / 8 VAL A  19
PHE A  43
HIS A  46
THR A  47
TYR A  84
VAL A 231
 None
 0.53A 3fhxB-1rfvA:
47.7		 3fhxB-1rfvA:
86.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		6 / 8 VAL A  19
VAL A  41
PHE A  43
HIS A  46
THR A  47
VAL A 231
 None
 0.49A 3fhxB-1rfvA:
47.7		 3fhxB-1rfvA:
86.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		5 / 12 ILE A 146
ALA A 238
LEU A 241
LEU A 252
ALA A 309
 None
 1.23A 3ozuA-1rfvA:
undetectable		 3ozuA-1rfvA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		4 / 8 LEU A   8
VAL A  94
LEU A  69
TYR A  77
 None
 1.01A 3v81A-1rfvA:
undetectable		 3v81A-1rfvA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		4 / 8 LEU A   8
VAL A  94
LEU A  69
TYR A  77
 None
 0.96A 3v81C-1rfvA:
undetectable		 3v81C-1rfvA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		5 / 11 GLY A 122
ALA A  23
GLY A  20
VAL A  14
VAL A 231
 None
 1.39A 4c5lA-1rfvA:
26.5		 4c5lA-1rfvA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		5 / 10 GLY A 122
ALA A  23
GLY A  20
VAL A  14
VAL A 231
 None
 1.41A 4c5lC-1rfvA:
27.0		 4c5lC-1rfvA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		5 / 10 GLY A 122
ALA A  23
GLY A  20
VAL A  14
VAL A 231
 None
 1.43A 4c5lD-1rfvA:
26.9		 4c5lD-1rfvA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		5 / 10 GLY A 122
ALA A  23
GLY A  20
VAL A  14
VAL A 231
 None
 1.36A 4c5nD-1rfvA:
26.9		 4c5nD-1rfvA:
26.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		5 / 5 SER A  12
GLY A  20
THR A  47
VAL A 231
ASP A 235
 None
 0.69A 4eohA-1rfvA:
48.0		 4eohA-1rfvA:
86.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EOH_B_TEPB402_1
(PYRIDOXAL KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		4 / 5 HIS A  46
TYR A  84
VAL A 231
ASP A 235
 None
 0.33A 4eohB-1rfvA:
47.8		 4eohB-1rfvA:
86.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EOH_B_TEPB402_1
(PYRIDOXAL KINASE)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		4 / 5 SER A  12
HIS A  46
VAL A 231
ASP A 235
 None
 0.69A 4eohB-1rfvA:
47.8		 4eohB-1rfvA:
86.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		4 / 8 LEU A   8
VAL A  94
LEU A  69
TYR A  77
 None
 0.92A 4puoC-1rfvA:
undetectable		 4puoC-1rfvA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		4 / 8 LEU A   8
VAL A  94
LEU A  69
TYR A  77
 None
 0.99A 4pwdC-1rfvA:
undetectable		 4pwdC-1rfvA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		5 / 12 SER A  12
GLN A  42
ALA A 125
GLY A 124
THR A  47
 None
 0.91A 5l66H-1rfvA:
undetectable
5l66I-1rfvA:
undetectable		 5l66H-1rfvA:
22.78
5l66I-1rfvA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		5 / 12 SER A  12
GLN A  42
ALA A 125
GLY A 124
THR A  47
 None
 0.91A 5l66V-1rfvA:
undetectable
5l66W-1rfvA:
undetectable		 5l66V-1rfvA:
22.78
5l66W-1rfvA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		3 / 3 VAL A 307
VAL A 306
GLN A 268
 None
 0.65A 5qglA-1rfvA:
undetectable		 5qglA-1rfvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		3 / 3 VAL A 307
VAL A 306
GLN A 268
 None
 0.68A 5qguA-1rfvA:
undetectable		 5qguA-1rfvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		3 / 3 VAL A 307
VAL A 306
GLN A 268
 None
 0.70A 5qh4A-1rfvA:
undetectable		 5qh4A-1rfvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		3 / 3 VAL A 307
VAL A 306
GLN A 268
 None
 0.70A 5qh9A-1rfvA:
undetectable		 5qh9A-1rfvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		3 / 3 VAL A 307
VAL A 306
GLN A 268
 None
 0.68A 5qhcA-1rfvA:
undetectable		 5qhcA-1rfvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		3 / 3 VAL A 307
VAL A 306
GLN A 268
 None
 0.70A 5qheA-1rfvA:
undetectable		 5qheA-1rfvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		3 / 3 VAL A 307
VAL A 306
GLN A 268
 None
 0.69A 5qhgA-1rfvA:
undetectable		 5qhgA-1rfvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 1rfv PYRIDOXAL KINASE
(Ovis
aries) 		3 / 3 ARG A 120
PHE A 237
LEU A 291
 None
ADP  A 401 (-4.1A)
None
 0.80A 5veuA-1rfvA:
undetectable		 5veuA-1rfvA:
21.15