SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rgi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 1rgi GELSOLIN
(Equus
caballus) 		3 / 3 VAL G  69
VAL G  46
TRP G  44
 None
 0.64A 1av2C-1rgiG:
undetectable
1av2D-1rgiG:
undetectable		 1av2C-1rgiG:
3.77
1av2D-1rgiG:
3.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MF1_A_ACTA458_0
(ADENYLOSUCCINATE
SYNTHETASE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 4 GLY G 313
LYS G 314
GLY G 310
HIS G 309
 None
 1.11A 1mf1A-1rgiG:
0.0		 1mf1A-1rgiG:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 1rgi GELSOLIN
(Equus
caballus) 		3 / 3 VAL G  69
VAL G  46
TRP G  44
 None
 0.72A 1w5uC-1rgiG:
undetectable
1w5uD-1rgiG:
undetectable		 1w5uC-1rgiG:
3.77
1w5uD-1rgiG:
3.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 4 HIS G  86
ASP G 109
ASN G 113
ASP G  84
 None
CA  G 404 (-2.8A)
None
None
 1.30A 1wg8A-1rgiG:
0.0		 1wg8A-1rgiG:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 1rgi GELSOLIN
(Equus
caballus) 		3 / 3 VAL G  46
TRP G  44
VAL G  69
 None
 0.70A 2izqA-1rgiG:
undetectable
2izqB-1rgiG:
undetectable		 2izqA-1rgiG:
3.77
2izqB-1rgiG:
3.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 7 PHE G 234
LEU G 244
LEU G 191
PHE G 183
 None
 0.85A 2vcvG-1rgiG:
undetectable		 2vcvG-1rgiG:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 5 LEU G  71
GLN G  82
THR G  73
THR G 105
 None
 1.05A 2zj0B-1rgiG:
undetectable		 2zj0B-1rgiG:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 5 LEU G  71
GLN G  82
THR G  73
THR G 105
 None
 1.05A 2zj0C-1rgiG:
undetectable		 2zj0C-1rgiG:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 4 LEU G  71
GLN G  82
THR G  73
THR G 105
 None
 1.05A 2zj0D-1rgiG:
undetectable		 2zj0D-1rgiG:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 5 LEU G  71
GLN G  82
THR G  73
THR G 105
 None
 1.07A 3ce6B-1rgiG:
undetectable		 3ce6B-1rgiG:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 7 PHE G 305
GLY G 320
PHE G 294
PHE G 366
 None
 1.07A 3ko0D-1rgiG:
undetectable
3ko0E-1rgiG:
undetectable		 3ko0D-1rgiG:
16.33
3ko0E-1rgiG:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 7 PHE G 305
GLY G 320
PHE G 294
PHE G 366
 None
 0.96A 3ko0M-1rgiG:
undetectable
3ko0P-1rgiG:
undetectable		 3ko0M-1rgiG:
16.33
3ko0P-1rgiG:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 1rgi GELSOLIN
(Equus
caballus) 		3 / 3 VAL G  69
VAL G  46
TRP G  44
 None
 0.79A 3l8lA-1rgiG:
undetectable
3l8lB-1rgiG:
undetectable		 3l8lA-1rgiG:
3.77
3l8lB-1rgiG:
3.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 1rgi GELSOLIN
(Equus
caballus) 		3 / 3 VAL G  69
VAL G  46
TRP G  44
 None
 0.87A 3l8lC-1rgiG:
undetectable
3l8lD-1rgiG:
undetectable		 3l8lC-1rgiG:
3.77
3l8lD-1rgiG:
3.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 5 GLN G 347
THR G 348
GLU G 175
THR G 174
 None
 1.44A 3n58A-1rgiG:
undetectable		 3n58A-1rgiG:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 5 ASP G 308
SER G 351
VAL G 350
GLY G 310
 None
 1.07A 3rxhA-1rgiG:
undetectable		 3rxhA-1rgiG:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1rgi GELSOLIN
(Equus
caballus) 		3 / 3 GLN G 164
GLU G 263
LYS G 166
 None
 1.09A 3su9A-1rgiG:
undetectable		 3su9A-1rgiG:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 8 PHE G 183
PRO G 251
GLY G 248
SER G 179
 None
 0.95A 3tzfB-1rgiG:
undetectable		 3tzfB-1rgiG:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 7 TYR G 133
ILE G  70
LEU G 138
GLY G  60
 None
 0.89A 4iqqA-1rgiG:
undetectable		 4iqqA-1rgiG:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 7 TYR G 133
ILE G  70
LEU G 138
GLY G  60
 None
 0.80A 4iqqB-1rgiG:
undetectable		 4iqqB-1rgiG:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 8 TYR G 133
ILE G  70
LEU G 138
GLY G  60
 None
 0.87A 4iqqD-1rgiG:
undetectable		 4iqqD-1rgiG:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 5 GLY G 148
ASP G  96
GLU G  47
VAL G  69
 None
 0.94A 4nkvD-1rgiG:
undetectable		 4nkvD-1rgiG:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 1rgi GELSOLIN
(Equus
caballus) 		5 / 12 PHE G 134
LEU G 138
TYR G 140
GLY G 132
SER G 127
 None
 1.32A 4zbrA-1rgiG:
undetectable		 4zbrA-1rgiG:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 4 LEU G 191
ARG G 225
ILE G 197
ILE G 220
 None
 0.72A 5dzk2-1rgiG:
undetectable
5dzkM-1rgiG:
undetectable
5dzkN-1rgiG:
undetectable		 5dzk2-1rgiG:
1.45
5dzkM-1rgiG:
19.43
5dzkN-1rgiG:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 5 LEU G 191
ARG G 225
ILE G 197
ILE G 220
 None
 0.77A 5dzk4-1rgiG:
undetectable
5dzkg-1rgiG:
undetectable
5dzkm-1rgiG:
undetectable
5dzkn-1rgiG:
undetectable		 5dzk4-1rgiG:
1.45
5dzkg-1rgiG:
21.77
5dzkm-1rgiG:
19.43
5dzkn-1rgiG:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 4 ILE G 197
ILE G 220
ARG G 225
LEU G 191
 None
 0.88A 5dzkh-1rgiG:
undetectable
5dzkn-1rgiG:
undetectable
5dzkv-1rgiG:
undetectable		 5dzkh-1rgiG:
19.43
5dzkn-1rgiG:
19.43
5dzkv-1rgiG:
1.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 5 ARG G 225
ILE G 197
ILE G 220
LEU G 191
 None
 0.85A 5dzki-1rgiG:
undetectable
5dzkj-1rgiG:
undetectable
5dzkx-1rgiG:
undetectable		 5dzki-1rgiG:
19.43
5dzkj-1rgiG:
19.43
5dzkx-1rgiG:
1.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 7 TYR G 133
ILE G  70
LEU G 138
GLY G  60
 None
 0.86A 5nooA-1rgiG:
undetectable		 5nooA-1rgiG:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 7 TYR G 133
ILE G  70
LEU G 138
GLY G  60
 None
 0.84A 5nooB-1rgiG:
undetectable		 5nooB-1rgiG:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 8 TYR G 133
ILE G  70
LEU G 138
GLY G  60
 None
 0.85A 5nooD-1rgiG:
undetectable		 5nooD-1rgiG:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 1rgi GELSOLIN
(Equus
caballus) 		4 / 8 GLU G  97
VAL G  46
GLY G  90
THR G  64
 CA  G 403 (-2.4A)
None
None
None
 0.87A 5sxtA-1rgiG:
undetectable		 5sxtA-1rgiG:
19.15