SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rh9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 6 TYR A 171
VAL A 268
ILE A 271
LEU A 179
 None
 1.20A 1j96A-1rh9A:
10.3		 1j96A-1rh9A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		6 / 12 THR A 275
ILE A 344
ILE A 340
TYR A 341
ILE A 125
ALA A  85
 None
 1.32A 1jtxA-1rh9A:
1.8		 1jtxA-1rh9A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		3 / 3 THR A 275
LEU A 315
LEU A  47
 None
 0.66A 1mz9C-1rh9A:
undetectable		 1mz9C-1rh9A:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		3 / 3 GLU A 318
ASN A  53
TRP A  88
 None
 1.23A 1r15C-1rh9A:
undetectable		 1r15C-1rh9A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		3 / 3 GLU A 318
ASN A  53
TRP A  88
 None
 1.28A 1r15D-1rh9A:
undetectable		 1r15D-1rh9A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		3 / 3 GLU A 318
ASN A  53
TRP A  88
 None
 1.24A 1r15E-1rh9A:
undetectable		 1r15E-1rh9A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		3 / 3 GLU A 318
ASN A  53
TRP A  88
 None
 1.23A 1r15F-1rh9A:
undetectable		 1r15F-1rh9A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 8 ASP A 158
GLY A 139
PHE A  90
TYR A 144
 None
 0.97A 2aouA-1rh9A:
undetectable		 2aouA-1rh9A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOW_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 7 GLN A 361
TYR A 279
TRP A  88
GLU A 204
 None
 1.29A 2aowA-1rh9A:
undetectable		 2aowA-1rh9A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		5 / 12 PHE A 359
ASN A  53
GLY A  51
PHE A 319
GLY A 320
 None
 1.20A 2fqyA-1rh9A:
undetectable		 2fqyA-1rh9A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 8 SER A 198
ARG A  86
ALA A 317
LEU A 358
 None
 1.03A 2o01A-1rh9A:
undetectable		 2o01A-1rh9A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		3 / 3 ARG A 333
SER A 381
TYR A 328
 None
 1.05A 2q2hA-1rh9A:
undetectable
2q2hB-1rh9A:
undetectable		 2q2hA-1rh9A:
15.16
2q2hB-1rh9A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		6 / 12 ASN A 203
GLU A 204
HIS A 277
TYR A 279
GLU A 318
TRP A 360
 None
 0.81A 2v3dA-1rh9A:
19.2		 2v3dA-1rh9A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		5 / 11 ASN A 203
GLU A 204
TYR A 279
GLU A 318
TRP A 360
 None
 0.89A 2v3dB-1rh9A:
16.3		 2v3dB-1rh9A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		3 / 3 MET A 367
VAL A 362
GLU A 380
 None
 0.81A 3c6gA-1rh9A:
0.0		 3c6gA-1rh9A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 5 TYR A 341
ILE A 128
LEU A 358
PHE A 319
 None
 1.28A 3ls4L-1rh9A:
undetectable		 3ls4L-1rh9A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 6 GLU A 237
ILE A 128
ALA A 317
ASN A 203
 None
 1.05A 3pgyA-1rh9A:
undetectable
3pgyB-1rh9A:
undetectable		 3pgyA-1rh9A:
23.03
3pgyB-1rh9A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		5 / 12 ALA A 348
PHE A  40
LEU A 236
PHE A 273
THR A  35
 None
 1.45A 4iaqA-1rh9A:
undetectable		 4iaqA-1rh9A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		3 / 3 ALA A 137
GLN A  99
GLY A 103
 None
 0.58A 4odoC-1rh9A:
undetectable		 4odoC-1rh9A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		5 / 12 ALA A  89
HIS A 277
GLU A 318
GLU A 200
LEU A 179
 None
 1.37A 4r7lA-1rh9A:
undetectable		 4r7lA-1rh9A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 7 ILE A 316
LEU A 315
GLY A 355
GLY A 356
 None
 0.79A 5a06A-1rh9A:
undetectable		 5a06A-1rh9A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 7 ILE A 316
LEU A 315
GLY A 355
GLY A 356
 None
 0.79A 5a06B-1rh9A:
undetectable		 5a06B-1rh9A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 7 ILE A 316
LEU A 315
GLY A 355
GLY A 356
 None
 0.79A 5a06C-1rh9A:
undetectable		 5a06C-1rh9A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 7 ILE A 316
LEU A 315
GLY A 355
GLY A 356
 None
 0.79A 5a06E-1rh9A:
undetectable		 5a06E-1rh9A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 7 ILE A 316
LEU A 315
GLY A 355
GLY A 356
 None
 0.80A 5a06F-1rh9A:
undetectable		 5a06F-1rh9A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 4 ILE A 276
GLY A 356
ILE A 300
LEU A 315
 None
 0.85A 5dzkl-1rh9A:
undetectable
5dzkz-1rh9A:
undetectable		 5dzkl-1rh9A:
17.69
5dzkz-1rh9A:
0.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		5 / 12 TYR A 171
ALA A 224
VAL A 220
LEU A 179
ILE A 196
 None
 1.24A 5hv1A-1rh9A:
1.5		 5hv1A-1rh9A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		5 / 10 ILE A 388
GLY A 320
PHE A 359
GLY A  51
VAL A 376
 None
 1.25A 5i6xA-1rh9A:
undetectable		 5i6xA-1rh9A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		3 / 3 SER A  91
LEU A 127
MET A 129
 None
 0.85A 5ikrB-1rh9A:
undetectable		 5ikrB-1rh9A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 8 VAL A 268
GLY A 239
LEU A 240
THR A 275
 None
 0.82A 5sxtA-1rh9A:
undetectable		 5sxtA-1rh9A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 8 VAL A 268
GLY A 239
LEU A 240
THR A 275
 None
 0.82A 5sxtB-1rh9A:
undetectable		 5sxtB-1rh9A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		4 / 8 SER A 381
THR A 384
PHE A 337
VAL A 387
 None
 1.09A 5vkqB-1rh9A:
undetectable
5vkqC-1rh9A:
undetectable		 5vkqB-1rh9A:
12.29
5vkqC-1rh9A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		5 / 12 TYR A 190
GLY A 112
ASN A 106
ASP A  63
ASP A 114
 None
 1.35A 5yn6A-1rh9A:
undetectable		 5yn6A-1rh9A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1rh9 ENDO-BETA-MANNANASE
(Solanum
lycopersicum) 		5 / 7 PHE A 319
ILE A 316
PHE A 273
LEU A 315
ILE A 388
 None
 1.35A 6b5vA-1rh9A:
undetectable
6b5vB-1rh9A:
undetectable		 6b5vA-1rh9A:
11.80
6b5vB-1rh9A:
11.80