SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rhf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 1rhf TYROSINE-PROTEIN
KINASE RECEPTOR
TYRO3
(Homo
sapiens) 		5 / 10 VAL A 152
LEU A 108
VAL A 110
VAL A 179
LEU A 118
 None
 0.98A 3gwxA-1rhfA:
undetectable		 3gwxA-1rhfA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1rhf TYROSINE-PROTEIN
KINASE RECEPTOR
TYRO3
(Homo
sapiens) 		4 / 8 SER A 146
ILE A 131
TRP A 133
GLU A 121
 None
 1.05A 4cx7C-1rhfA:
0.0
4cx7D-1rhfA:
0.0		 4cx7C-1rhfA:
18.03
4cx7D-1rhfA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1rhf TYROSINE-PROTEIN
KINASE RECEPTOR
TYRO3
(Homo
sapiens) 		4 / 5 GLN A  89
VAL A  91
TRP A  92
THR A  94
 None
 1.08A 6cduI-1rhfA:
1.0
6cduJ-1rhfA:
0.7		 6cduI-1rhfA:
22.22
6cduJ-1rhfA:
22.22