SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rhi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		5 / 12 ILE 3  87
PHE 3  92
SER 3 114
ILE 3 113
LEU 3 187
 None
 1.22A 1rh3A-1rhi3:
undetectable		 1rh3A-1rhi3:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		5 / 12 LEU 2  82
ALA 2  85
LYS 2  87
LEU 2  86
VAL 2 242
 None
 1.16A 1sa1A-1rhi2:
undetectable
1sa1B-1rhi2:
undetectable		 1sa1A-1rhi2:
18.78
1sa1B-1rhi2:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		5 / 8 LEU 2 181
ALA 2 169
ILE 2 170
GLY 2 175
HIS 2 130
 None
 1.36A 1sv9A-1rhi2:
undetectable		 1sv9A-1rhi2:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		4 / 6 ASN 2 190
LEU 3  52
LEU 3 207
ILE 2 225
 None
 1.01A 1z95A-1rhi2:
undetectable		 1z95A-1rhi2:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		4 / 6 HIS 2  99
PHE 2 251
ARG 2 257
GLY 2  93
 None
 1.34A 2i30A-1rhi2:
undetectable		 2i30A-1rhi2:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		5 / 9 TYR 1 128
LEU 1 116
ALA 1  75
ALA 1 247
PHE 1 124
 None
 1.29A 2vcvH-1rhi1:
undetectable		 2vcvH-1rhi1:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		3 / 3 HIS 2 130
MET 2 221
MET 2 173
 None
 1.25A 2vj1A-1rhi2:
undetectable		 2vj1A-1rhi2:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9W_A_PXLA1197_1
(ASPARTATE
AMINOTRANSFERASE)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		5 / 11 PRO 3  54
LEU 2 177
VAL 1 279
ASN 3  57
LYS 1 281
 None
 1.17A 2z9wA-1rhi3:
undetectable		 2z9wA-1rhi3:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9W_B_PXLB1197_1
(ASPARTATE
AMINOTRANSFERASE)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		5 / 11 PRO 3  54
LEU 2 177
VAL 1 279
ASN 3  57
LYS 1 281
 None
 1.20A 2z9wB-1rhi3:
undetectable		 2z9wB-1rhi3:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		5 / 9 ALA 2  85
ASN 2 216
SER 2 219
LEU 2 132
VAL 2 142
 None
 1.36A 3claA-1rhi2:
0.0		 3claA-1rhi2:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		4 / 5 GLN 3 226
THR 3 225
GLU 3  99
THR 3  95
 None
 1.11A 3glqA-1rhi3:
undetectable		 3glqA-1rhi3:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		4 / 5 GLN 3 226
THR 3 225
GLU 3  99
THR 3  95
 None
 1.19A 3glqB-1rhi3:
undetectable		 3glqB-1rhi3:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B;
Rhinovirus
B) 		3 / 3 GLU 1  68
ASP 3  18
ASP 1 125
 None
 0.61A 3jb2A-1rhi1:
undetectable		 3jb2A-1rhi1:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		5 / 10 ILE 3 211
PHE 3  92
ILE 3  87
ILE 3 165
SER 3 209
 None
 1.31A 3o1xA-1rhi3:
undetectable		 3o1xA-1rhi3:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		5 / 10 ILE 3 211
PHE 3  92
ILE 3  87
ILE 3 165
SER 3 209
 None
 1.27A 3qgzA-1rhi3:
undetectable		 3qgzA-1rhi3:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		5 / 11 LEU 1 146
SER 1 144
THR 1 237
THR 1 236
ASN 1  84
 None
 1.30A 3sfuC-1rhi1:
undetectable		 3sfuC-1rhi1:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B;
Rhinovirus
B) 		4 / 6 THR 1  42
GLY 1  40
ILE 2  32
LEU 2 182
 None
 0.90A 4acbC-1rhi1:
undetectable		 4acbC-1rhi1:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		4 / 7 ASN 2 190
LEU 3  52
LEU 3 207
ILE 2 225
 None
 1.03A 4okwA-1rhi2:
undetectable		 4okwA-1rhi2:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		3 / 3 ASP 2  57
LEU 2  18
GLY 2  19
 None
 0.54A 4xmfA-1rhi2:
0.0		 4xmfA-1rhi2:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		3 / 3 LYS 3 218
ARG 3 220
HIS 3 106
 None
 0.89A 4zbrA-1rhi3:
undetectable		 4zbrA-1rhi3:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
HUMAN RHINOVIRUS 3
COAT PROTEIN
HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B;
Rhinovirus
B;
Rhinovirus
B) 		5 / 7 GLY 2 179
LEU 2 178
ILE 2 225
LEU 3 208
ILE 1 285
 None
 1.31A 5vkqA-1rhi2:
undetectable
5vkqB-1rhi2:
undetectable		 5vkqA-1rhi2:
9.77
5vkqB-1rhi2:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		5 / 12 VAL 2  60
PRO 3  37
VAL 2 126
PHE 2  92
PRO 2  83
 None
 1.24A 6becA-1rhi2:
3.5
6becB-1rhi2:
2.7
6becC-1rhi2:
0.0		 6becA-1rhi2:
19.47
6becB-1rhi2:
19.47
6becC-1rhi2:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		3 / 3 ILE 2 225
ASN 2 172
CYH 2  79
 None
 0.92A 6bp4A-1rhi2:
0.0		 6bp4A-1rhi2:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
HUMAN RHINOVIRUS 3
COAT PROTEIN
HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B;
Rhinovirus
B;
Rhinovirus
B) 		5 / 12 HIS 2 186
GLY 1  40
ARG 1 256
LEU 3  96
GLY 3  50
 None
 1.05A 6c2mA-1rhi2:
undetectable		 6c2mA-1rhi2:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		5 / 8 ILE 2  58
PRO 2  56
ALA 2 245
THR 2 107
TYR 2 106
 None
 1.37A 6cduD-1rhi2:
undetectable
6cduE-1rhi2:
undetectable		 6cduD-1rhi2:
19.51
6cduE-1rhi2:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		6 / 12 LEU 3 208
GLY 3 119
ILE 3 155
SER 3 123
VAL 3 205
LEU 3  71
 None
 1.32A 6ectA-1rhi3:
undetectable		 6ectA-1rhi3:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		6 / 12 LEU 3 208
GLY 3 119
ILE 3 155
SER 3 123
VAL 3 205
LEU 3  71
 None
 1.30A 6ecxA-1rhi3:
undetectable		 6ecxA-1rhi3:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
(Rhinovirus
B) 		3 / 3 LEU 1  71
SER 1  69
PHE 1  70
 None
 0.59A 6fgcA-1rhi1:
undetectable		 6fgcA-1rhi1:
20.42