SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rhx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 1rhx CONSERVED
HYPOTHETICAL PROTEIN
TM0979
(Thermotoga
maritima) 		4 / 8 HIS A  12
LEU A  30
LEU A   3
GLU A  15
 None
 0.78A 1i7zA-1rhxA:
undetectable		 1i7zA-1rhxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 1rhx CONSERVED
HYPOTHETICAL PROTEIN
TM0979
(Thermotoga
maritima) 		4 / 6 ASP A  54
GLY A  87
ILE A  86
PRO A  13
 None
 0.91A 1n49D-1rhxA:
undetectable		 1n49D-1rhxA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 1rhx CONSERVED
HYPOTHETICAL PROTEIN
TM0979
(Thermotoga
maritima) 		5 / 11 GLY A   9
PHE A  36
LEU A  39
VAL A  14
HIS A  12
 None
 1.09A 1ukbA-1rhxA:
undetectable		 1ukbA-1rhxA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 1rhx CONSERVED
HYPOTHETICAL PROTEIN
TM0979
(Thermotoga
maritima) 		5 / 9 ASP A  54
GLY A  87
ILE A  86
PRO A  13
VAL A  14
 None
 1.08A 3ekyB-1rhxA:
undetectable		 3ekyB-1rhxA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 1rhx CONSERVED
HYPOTHETICAL PROTEIN
TM0979
(Thermotoga
maritima) 		5 / 11 ASP A  54
GLY A  87
ILE A  86
PRO A  13
VAL A  14
 None
 1.05A 3el1A-1rhxA:
undetectable		 3el1A-1rhxA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1rhx CONSERVED
HYPOTHETICAL PROTEIN
TM0979
(Thermotoga
maritima) 		4 / 5 ILE A  86
PHE A  75
ASP A  77
GLU A  80
 None
 1.07A 3kp6A-1rhxA:
undetectable
3kp6B-1rhxA:
undetectable		 3kp6A-1rhxA:
20.26
3kp6B-1rhxA:
20.26