SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ri3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 LEU A  71
PHE A 147
ILE A 155
ILE A 160
MET A 233
 None
 1.38A 1osvB-1ri3A:
0.0		 1osvB-1ri3A:
22.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 GLY A  92
ALA A 120
ASP A 122
SER A 123
TYR A 124
 None
None
SAH  A 299 (-3.2A)
SAH  A 299 (-3.1A)
SAH  A 299 (-4.0A)
 1.19A 1ri4A-1ri3A:
43.3		 1ri4A-1ri3A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		12 / 12 LYS A  54
GLY A  72
GLY A  74
ILE A  95
ALA A  96
ASP A 122
SER A 123
TYR A 124
GLN A 140
PHE A 141
SER A 142
TYR A 145
 SAH  A 299 (-3.0A)
SAH  A 299 (-3.3A)
SAH  A 299 (-3.5A)
SAH  A 299 (-3.8A)
SAH  A 299 ( 3.8A)
SAH  A 299 (-3.2A)
SAH  A 299 (-3.1A)
SAH  A 299 (-4.0A)
None
None
SAH  A 299 (-3.0A)
SAH  A 299 (-4.2A)
 0.41A 1ri4A-1ri3A:
43.3		 1ri4A-1ri3A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 LEU A  71
ASP A  94
ILE A 100
GLY A  74
TYR A  90
 None
SAH  A 299 (-2.9A)
None
SAH  A 299 (-3.5A)
None
 1.41A 1s9aB-1ri3A:
undetectable		 1s9aB-1ri3A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		4 / 6 ARG A 232
SER A 152
ARG A 210
GLU A 151
 None
 1.46A 2c8aC-1ri3A:
undetectable		 2c8aC-1ri3A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		4 / 6 SER A 150
SER A 152
ARG A 210
GLU A 151
 None
 1.42A 2c8aC-1ri3A:
undetectable		 2c8aC-1ri3A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 GLY A  72
GLY A  74
ILE A  95
ASP A 122
TYR A 145
 SAH  A 299 (-3.3A)
SAH  A 299 (-3.5A)
SAH  A 299 (-3.8A)
SAH  A 299 (-3.2A)
SAH  A 299 (-4.2A)
 0.67A 2qe6A-1ri3A:
13.7		 2qe6A-1ri3A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 GLY A  72
GLY A  74
ILE A  95
ASP A 122
TYR A 145
 SAH  A 299 (-3.3A)
SAH  A 299 (-3.5A)
SAH  A 299 (-3.8A)
SAH  A 299 (-3.2A)
SAH  A 299 (-4.2A)
 0.47A 2qe6B-1ri3A:
13.8		 2qe6B-1ri3A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 11 LEU A  57
THR A  62
VAL A  68
ASP A  70
VAL A 136
 None
None
None
SAH  A 299 ( 4.9A)
None
 1.06A 3lxiB-1ri3A:
undetectable		 3lxiB-1ri3A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		3 / 3 GLY A  74
ASP A  94
ASP A 122
 SAH  A 299 (-3.5A)
SAH  A 299 (-2.9A)
SAH  A 299 (-3.2A)
 0.29A 3ou7C-1ri3A:
14.9		 3ou7C-1ri3A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 9 GLY A  76
GLY A  77
ASN A  51
SER A  99
GLY A  74
 None
None
None
SAH  A 299 ( 4.2A)
SAH  A 299 (-3.5A)
 1.31A 3ztvA-1ri3A:
undetectable		 3ztvA-1ri3A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 GLY A  72
GLY A  76
GLY A  77
ASP A  94
ASP A 122
 SAH  A 299 (-3.3A)
None
None
SAH  A 299 (-2.9A)
SAH  A 299 (-3.2A)
 0.85A 4b17A-1ri3A:
10.1		 4b17A-1ri3A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 LEU A  57
THR A  62
VAL A  68
ASP A  70
VAL A 136
 None
None
None
SAH  A 299 ( 4.9A)
None
 0.99A 4c9lA-1ri3A:
undetectable		 4c9lA-1ri3A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 LEU A  57
THR A  62
VAL A  68
ASP A  70
VAL A 136
 None
None
None
SAH  A 299 ( 4.9A)
None
 0.99A 4c9lB-1ri3A:
undetectable		 4c9lB-1ri3A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 LEU A  57
THR A  62
VAL A  68
ASP A  70
VAL A 136
 None
None
None
SAH  A 299 ( 4.9A)
None
 1.02A 4c9oA-1ri3A:
undetectable		 4c9oA-1ri3A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 LEU A  57
THR A  62
VAL A  68
ASP A  70
VAL A 136
 None
None
None
SAH  A 299 ( 4.9A)
None
 1.02A 4c9oB-1ri3A:
undetectable		 4c9oB-1ri3A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 GLY A  72
GLY A  74
VAL A  93
SER A 142
TYR A 145
 SAH  A 299 (-3.3A)
SAH  A 299 (-3.5A)
None
SAH  A 299 (-3.0A)
SAH  A 299 (-4.2A)
 0.79A 4f84A-1ri3A:
16.9		 4f84A-1ri3A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 GLY A  72
GLY A  74
ASP A  94
ILE A  95
ASP A 122
 SAH  A 299 (-3.3A)
SAH  A 299 (-3.5A)
SAH  A 299 (-2.9A)
SAH  A 299 (-3.8A)
SAH  A 299 (-3.2A)
 0.24A 4iv8A-1ri3A:
15.7		 4iv8A-1ri3A:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 GLY A  72
GLY A  74
ASP A  94
ILE A  95
ASP A 122
 SAH  A 299 (-3.3A)
SAH  A 299 (-3.5A)
SAH  A 299 (-2.9A)
SAH  A 299 (-3.8A)
SAH  A 299 (-3.2A)
 0.25A 4iv8B-1ri3A:
15.6		 4iv8B-1ri3A:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 GLY A  72
GLY A  74
ILE A  95
ALA A  96
PHE A 141
 SAH  A 299 (-3.3A)
SAH  A 299 (-3.5A)
SAH  A 299 (-3.8A)
SAH  A 299 ( 3.8A)
None
 1.22A 4kicA-1ri3A:
15.3		 4kicA-1ri3A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		4 / 4 ASP A  70
GLY A  74
ASP A  94
ASP A 122
 SAH  A 299 ( 4.9A)
SAH  A 299 (-3.5A)
SAH  A 299 (-2.9A)
SAH  A 299 (-3.2A)
 0.74A 5e72A-1ri3A:
15.3		 5e72A-1ri3A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		4 / 7 THR A  62
VAL A  68
ASP A  70
VAL A 136
 None
None
SAH  A 299 ( 4.9A)
None
 0.76A 5ik1A-1ri3A:
undetectable		 5ik1A-1ri3A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		3 / 3 ARG A 106
ARG A 112
ARG A 104
 None
 0.89A 5vcgA-1ri3A:
1.1		 5vcgA-1ri3A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		4 / 8 THR A  62
VAL A  68
ASP A  70
VAL A 136
 None
None
SAH  A 299 ( 4.9A)
None
 0.77A 6cp4A-1ri3A:
undetectable		 6cp4A-1ri3A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 GLY A  72
GLY A  74
ASP A  78
ILE A  95
SER A 123
 SAH  A 299 (-3.3A)
SAH  A 299 (-3.5A)
SAH  A 299 (-4.0A)
SAH  A 299 (-3.8A)
SAH  A 299 (-3.1A)
 0.50A 6ectA-1ri3A:
15.7		 6ectA-1ri3A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 GLY A  72
GLY A  74
ASP A  78
ILE A  95
SER A 123
 SAH  A 299 (-3.3A)
SAH  A 299 (-3.5A)
SAH  A 299 (-4.0A)
SAH  A 299 (-3.8A)
SAH  A 299 (-3.1A)
 0.50A 6ecxA-1ri3A:
15.6		 6ecxA-1ri3A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		3 / 3 VAL A 280
GLU A 279
ILE A  46
 None
 0.58A 6f7lB-1ri3A:
undetectable		 6f7lB-1ri3A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 1ri3 MRNA CAPPING ENZYME
(Encephalitozoon
cuniculi) 		5 / 12 ASP A  70
GLY A  72
GLY A  74
ALA A  96
ASP A 122
 SAH  A 299 ( 4.9A)
SAH  A 299 (-3.3A)
SAH  A 299 (-3.5A)
SAH  A 299 ( 3.8A)
SAH  A 299 (-3.2A)
 0.66A 6nj9K-1ri3A:
10.3		 6nj9K-1ri3A:
22.44