SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ri7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ri7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Pyrococcus
horikoshii) 		3 / 3 GLU A 112
TYR A 110
PHE A 140
 None
 0.80A 1eqbB-1ri7A:
undetectable		 1eqbB-1ri7A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ri7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Pyrococcus
horikoshii) 		3 / 3 GLU A 112
TYR A 110
PHE A 140
 None
 0.80A 1eqbA-1ri7A:
undetectable		 1eqbA-1ri7A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ri7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Pyrococcus
horikoshii) 		3 / 3 GLU A 112
TYR A 110
PHE A 140
 None
 0.80A 1eqbD-1ri7A:
undetectable		 1eqbD-1ri7A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ri7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Pyrococcus
horikoshii) 		3 / 3 GLU A 112
TYR A 110
PHE A 140
 None
 0.81A 1eqbC-1ri7A:
undetectable		 1eqbC-1ri7A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1ri7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Pyrococcus
horikoshii) 		3 / 3 LYS A 128
LEU A  88
ARG A 130
 None
 0.88A 5yw0A-1ri7A:
undetectable		 5yw0A-1ri7A:
19.54