SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rj6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 7 HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.29A 1am6A-1rj6A:
37.1		 1am6A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 7 HIS A  94
HIS A 119
LEU A 198
THR A 199
 ZN  A 601 ( 3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.09A 1am6A-1rj6A:
37.1		 1am6A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 8 HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.31A 1azmA-1rj6A:
36.0		 1azmA-1rj6A:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 8 HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.31A 1bzmA-1rj6A:
35.9		 1bzmA-1rj6A:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.08A 1cilA-1rj6A:
37.1		 1cilA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.14A 1cilA-1rj6A:
37.1		 1cilA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 HIS A  64
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.46A 1cilA-1rj6A:
37.1		 1cilA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 HIS A  64
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.02A 1cilA-1rj6A:
37.1		 1cilA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.43A 1cilA-1rj6A:
37.1		 1cilA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 141
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.44A 1dmyA-1rj6A:
33.3		 1dmyA-1rj6A:
33.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.14A 1dmyB-1rj6A:
33.3		 1dmyB-1rj6A:
33.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.42A 1dmyB-1rj6A:
33.3		 1dmyB-1rj6A:
33.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 8 LEU A  95
ALA A 116
LEU A 118
THR A 210
 None
 0.90A 1dvtA-1rj6A:
undetectable
1dvtB-1rj6A:
undetectable		 1dvtA-1rj6A:
21.29
1dvtB-1rj6A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 8 ARG A 254
GLY A 145
PRO A  30
ILE A  31
ILE A  33
 None
 1.19A 1hshD-1rj6A:
undetectable		 1hshD-1rj6A:
14.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 9 GLN A  67
HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.90A 1jd0A-1rj6A:
40.6		 1jd0A-1rj6A:
44.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.33A 1jd0A-1rj6A:
40.6		 1jd0A-1rj6A:
44.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 9 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.46A 1jd0A-1rj6A:
40.6		 1jd0A-1rj6A:
44.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.00A 1jd0A-1rj6A:
40.6		 1jd0A-1rj6A:
44.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
HIS A 119
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.89A 1jd0B-1rj6A:
40.5		 1jd0B-1rj6A:
44.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.10A 1jd0B-1rj6A:
40.5		 1jd0B-1rj6A:
44.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.41A 1jd0B-1rj6A:
40.5		 1jd0B-1rj6A:
44.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.98A 1jd0B-1rj6A:
40.5		 1jd0B-1rj6A:
44.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.42A 1jd0B-1rj6A:
40.5		 1jd0B-1rj6A:
44.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 ASN A 213
GLN A 188
THR A  35
ILE A 109
PHE A 192
 None
 1.17A 1m2zD-1rj6A:
undetectable		 1m2zD-1rj6A:
24.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 ASN A  62
GLN A  67
HIS A  96
LEU A 198
THR A 199
PRO A 202
 None
None
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 1.34A 1oq5A-1rj6A:
37.3		 1oq5A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 ASN A  62
HIS A  96
LEU A 198
THR A 199
PRO A 202
TRP A 209
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
None
 1.34A 1oq5A-1rj6A:
37.3		 1oq5A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
PRO A 202
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 1.13A 1oq5A-1rj6A:
37.3		 1oq5A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
PRO A 202
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
None
 0.48A 1oq5A-1rj6A:
37.3		 1oq5A-1rj6A:
37.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 ASN A 213
GLN A 188
THR A  35
ILE A 109
PHE A 192
 None
 1.18A 1p93B-1rj6A:
undetectable		 1p93B-1rj6A:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 ASN A 213
GLN A 188
THR A  35
ILE A 109
PHE A 192
 None
 1.11A 1p93D-1rj6A:
undetectable		 1p93D-1rj6A:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 ILE A 146
ILE A 148
ALA A 216
LEU A 184
LEU A 161
 None
 1.14A 1xzxX-1rj6A:
0.0		 1xzxX-1rj6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 LEU A 208
ASN A 195
ALA A  27
GLN A  28
ARG A 246
 None
NAG  A 801 (-1.9A)
None
None
None
 1.46A 1ya3A-1rj6A:
undetectable		 1ya3A-1rj6A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 LEU A 208
ASN A 195
ALA A  27
GLN A  28
ARG A 246
 None
NAG  A 801 (-1.9A)
None
None
None
 1.44A 1ya3B-1rj6A:
undetectable		 1ya3B-1rj6A:
20.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 10 GLN A  92
HIS A  94
HIS A 119
VAL A 121
VAL A 143
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.38A 1ydaA-1rj6A:
36.5		 1ydaA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.14A 1ydbA-1rj6A:
36.8		 1ydbA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.38A 1ydbA-1rj6A:
36.8		 1ydbA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 HIS A  96
HIS A  94
VAL A 121
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.46A 1ydbA-1rj6A:
36.8		 1ydbA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.08A 1yddA-1rj6A:
37.1		 1yddA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.04A 1yddA-1rj6A:
37.1		 1yddA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
THR A 199
THR A 200
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.34A 1yddA-1rj6A:
37.1		 1yddA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  96
HIS A  94
VAL A 121
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.44A 1yddA-1rj6A:
37.1		 1yddA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.07A 1z9yA-1rj6A:
37.0		 1z9yA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.15A 1z9yA-1rj6A:
37.0		 1z9yA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.45A 1z9yA-1rj6A:
37.0		 1z9yA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 ASN A  62
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.09A 1zgfA-1rj6A:
37.2		 1zgfA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.08A 1zgfA-1rj6A:
37.2		 1zgfA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.19A 1zgfA-1rj6A:
37.2		 1zgfA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.38A 1zgfA-1rj6A:
37.2		 1zgfA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
HIS A 119
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.91A 1zsbA-1rj6A:
37.3		 1zsbA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.13A 1zsbA-1rj6A:
37.3		 1zsbA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.34A 1zsbA-1rj6A:
37.3		 1zsbA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.49A 1zsbA-1rj6A:
37.3		 1zsbA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.10A 2aw1A-1rj6A:
37.1		 2aw1A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.19A 2aw1A-1rj6A:
37.1		 2aw1A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
None
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.36A 2aw1A-1rj6A:
37.1		 2aw1A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 6 ASN A  62
GLN A  67
THR A 200
PRO A 202
 None
None
AZM  A 400 (-3.6A)
None
 1.34A 2ez7A-1rj6A:
36.9		 2ez7A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 6 TRP A   5
GLN A  67
THR A 200
PRO A 202
 None
None
AZM  A 400 (-3.6A)
None
 1.20A 2ez7A-1rj6A:
36.9		 2ez7A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 6 TRP A   5
GLN A  92
THR A 200
PRO A 202
 None
AZM  A 400 (-4.3A)
AZM  A 400 (-3.6A)
None
 0.50A 2ez7A-1rj6A:
36.9		 2ez7A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.34A 2gehA-1rj6A:
37.0		 2gehA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 GLN A  67
HIS A  96
HIS A 119
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.83A 2h4nA-1rj6A:
37.4		 2h4nA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 9 GLN A  92
HIS A  96
HIS A 119
VAL A 121
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.33A 2h4nA-1rj6A:
37.4		 2h4nA-1rj6A:
36.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 ILE A 146
ILE A 148
ALA A 216
ALA A 156
LEU A 184
 None
 0.99A 2h79A-1rj6A:
undetectable		 2h79A-1rj6A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 ILE A 146
ILE A 148
ALA A 216
LEU A 184
LEU A 161
 None
 1.08A 2h79A-1rj6A:
undetectable		 2h79A-1rj6A:
22.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 6 ASN A  62
HIS A  64
GLN A  92
THR A 200
 None
None
AZM  A 400 (-4.3A)
AZM  A 400 (-3.6A)
 0.81A 2hkkA-1rj6A:
37.1		 2hkkA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 143
LEU A 198
THR A 199
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 0.34A 2it4A-1rj6A:
36.1		 2it4A-1rj6A:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 8 HIS A  96
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 0.84A 2it4A-1rj6A:
36.1		 2it4A-1rj6A:
35.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 LEU A 118
ILE A 160
LEU A  79
PRO A  49
VAL A  47
 None
 1.06A 2po5A-1rj6A:
undetectable		 2po5A-1rj6A:
20.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 ASN A  62
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.07A 2pouA-1rj6A:
37.2		 2pouA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.11A 2pouA-1rj6A:
37.2		 2pouA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.18A 2pouA-1rj6A:
37.2		 2pouA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.40A 2pouA-1rj6A:
37.2		 2pouA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.60A 3bl1A-1rj6A:
37.0		 3bl1A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.14A 3bl1A-1rj6A:
37.0		 3bl1A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.18A 3bl1A-1rj6A:
37.0		 3bl1A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 0.40A 3cajA-1rj6A:
37.1		 3cajA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  94
HIS A 119
THR A 199
PRO A 201
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.6A)
None
None
 1.30A 3cajA-1rj6A:
37.1		 3cajA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.99A 3cajA-1rj6A:
37.1		 3cajA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 0.86A 3czvA-1rj6A:
36.9
3czvB-1rj6A:
37.0		 3czvA-1rj6A:
37.17
3czvB-1rj6A:
37.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.18A 3czvA-1rj6A:
36.9
3czvB-1rj6A:
37.0		 3czvA-1rj6A:
37.17
3czvB-1rj6A:
37.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.44A 3czvA-1rj6A:
36.9
3czvB-1rj6A:
37.0		 3czvA-1rj6A:
37.17
3czvB-1rj6A:
37.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.49A 3czvA-1rj6A:
36.9
3czvB-1rj6A:
37.0		 3czvA-1rj6A:
37.17
3czvB-1rj6A:
37.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 0.95A 3czvB-1rj6A:
37.0		 3czvB-1rj6A:
37.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.24A 3czvB-1rj6A:
37.0		 3czvB-1rj6A:
37.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.38A 3czvB-1rj6A:
37.0		 3czvB-1rj6A:
37.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.48A 3czvB-1rj6A:
37.0		 3czvB-1rj6A:
37.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
 ZN  A 601 ( 3.2A)
ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.43A 3czvB-1rj6A:
37.0		 3czvB-1rj6A:
37.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.04A 3dazA-1rj6A:
37.3		 3dazA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.36A 3dazA-1rj6A:
37.3		 3dazA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.02A 3dazA-1rj6A:
37.3		 3dazA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
HIS A 119
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.93A 3dc3A-1rj6A:
37.3		 3dc3A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.14A 3dc3A-1rj6A:
37.3		 3dc3A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.36A 3dc3A-1rj6A:
37.3		 3dc3A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.94A 3dcsA-1rj6A:
37.3		 3dcsA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.34A 3dcsA-1rj6A:
37.3		 3dcsA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 0.37A 3dcwA-1rj6A:
37.3		 3dcwA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  94
HIS A 119
THR A 199
PRO A 201
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.6A)
None
None
 1.32A 3dcwA-1rj6A:
37.3		 3dcwA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.85A 3dcwA-1rj6A:
37.3		 3dcwA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 0.39A 3dd0A-1rj6A:
37.2		 3dd0A-1rj6A:
37.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 ARG A 254
ILE A 109
GLY A 145
ILE A  31
ILE A  33
 None
 0.96A 3ebzA-1rj6A:
0.0		 3ebzA-1rj6A:
14.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 0.64A 3f4xA-1rj6A:
36.9		 3f4xA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 ASN A  62
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 1.07A 3f4xA-1rj6A:
36.9		 3f4xA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.14A 3f4xA-1rj6A:
36.9		 3f4xA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.23A 3f4xA-1rj6A:
36.9		 3f4xA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 HIS A  94
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 601 ( 3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 1.50A 3f4xA-1rj6A:
36.9		 3f4xA-1rj6A:
37.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_G_TOPG200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 ASN A 195
LEU A 208
LEU A  84
VAL A  47
LEU A  44
PHE A 191
 NAG  A 801 (-1.9A)
None
None
None
None
None
 1.36A 3fl9G-1rj6A:
undetectable		 3fl9G-1rj6A:
19.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 ASN A  62
HIS A  64
GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.69A 3fw3A-1rj6A:
34.1		 3fw3A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 HIS A  64
GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.90A 3fw3A-1rj6A:
34.1		 3fw3A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 HIS A  64
GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.12A 3fw3A-1rj6A:
34.1		 3fw3A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.59A 3fw3B-1rj6A:
33.9		 3fw3B-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.07A 3fw3B-1rj6A:
33.9		 3fw3B-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.19A 3fw3B-1rj6A:
33.9		 3fw3B-1rj6A:
35.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 ILE A 146
ILE A 148
ALA A 216
ALA A 156
LEU A 184
 None
 0.96A 3gwsX-1rj6A:
0.0		 3gwsX-1rj6A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 4 LEU A  70
PRO A  71
LEU A  77
ARG A 182
 None
 1.09A 3hcoB-1rj6A:
undetectable		 3hcoB-1rj6A:
20.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 200
TRP A 209
 None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.64A 3hkuA-1rj6A:
37.2		 3hkuA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.11A 3hkuA-1rj6A:
37.2		 3hkuA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.16A 3hkuA-1rj6A:
37.2		 3hkuA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.50A 3hkuA-1rj6A:
37.2		 3hkuA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		3 / 3 GLU A 106
HIS A 119
THR A 199
 ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.6A)
 0.28A 3hkuA-1rj6A:
37.2		 3hkuA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.05A 3hs4A-1rj6A:
37.4		 3hs4A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.13A 3hs4A-1rj6A:
37.4		 3hs4A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.36A 3hs4A-1rj6A:
37.4		 3hs4A-1rj6A:
37.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 4 ILE A 109
ARG A 193
ILE A  33
THR A 114
 None
 0.80A 3ia4C-1rj6A:
undetectable		 3ia4C-1rj6A:
20.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.07A 3iaiA-1rj6A:
38.1		 3iaiA-1rj6A:
45.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.47A 3iaiA-1rj6A:
38.1		 3iaiA-1rj6A:
45.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.01A 3iaiA-1rj6A:
38.1		 3iaiA-1rj6A:
45.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.07A 3iaiB-1rj6A:
38.3		 3iaiB-1rj6A:
45.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.46A 3iaiB-1rj6A:
38.3		 3iaiB-1rj6A:
45.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.00A 3iaiB-1rj6A:
38.3		 3iaiB-1rj6A:
45.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.07A 3iaiC-1rj6A:
38.3		 3iaiC-1rj6A:
45.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.44A 3iaiC-1rj6A:
38.3		 3iaiC-1rj6A:
45.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.00A 3iaiC-1rj6A:
38.3		 3iaiC-1rj6A:
45.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.07A 3iaiD-1rj6A:
38.4		 3iaiD-1rj6A:
45.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.45A 3iaiD-1rj6A:
38.4		 3iaiD-1rj6A:
45.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.99A 3iaiD-1rj6A:
38.4		 3iaiD-1rj6A:
45.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 GLN A  67
HIS A  94
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.23A 3kwaA-1rj6A:
36.9		 3kwaA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 11 GLN A  92
HIS A  94
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 0.41A 3kwaA-1rj6A:
36.9		 3kwaA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  94
HIS A 119
LEU A 198
THR A 199
PRO A 201
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
None
 1.41A 3kwaA-1rj6A:
36.9		 3kwaA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.96A 3kwaA-1rj6A:
36.9		 3kwaA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 0.83A 3lxeA-1rj6A:
36.4		 3lxeA-1rj6A:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.03A 3lxeA-1rj6A:
36.4		 3lxeA-1rj6A:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 143
LEU A 198
THR A 199
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.47A 3lxeA-1rj6A:
36.4		 3lxeA-1rj6A:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 0.83A 3lxeB-1rj6A:
36.3		 3lxeB-1rj6A:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.02A 3lxeB-1rj6A:
36.3		 3lxeB-1rj6A:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 143
LEU A 198
THR A 199
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.48A 3lxeB-1rj6A:
36.3		 3lxeB-1rj6A:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
ALA A 135
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 0.47A 3mdzA-1rj6A:
37.3		 3mdzA-1rj6A:
34.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 1.09A 3mdzA-1rj6A:
37.3		 3mdzA-1rj6A:
34.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.09A 3ml5A-1rj6A:
37.3		 3ml5A-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.15A 3ml5A-1rj6A:
37.3		 3ml5A-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.36A 3ml5A-1rj6A:
37.3		 3ml5A-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.42A 3ml5A-1rj6A:
37.3		 3ml5A-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.06A 3v2jA-1rj6A:
37.2		 3v2jA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.14A 3v2jA-1rj6A:
37.2		 3v2jA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.35A 3v2jA-1rj6A:
37.2		 3v2jA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.09A 3v2mA-1rj6A:
37.3		 3v2mA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.38A 3v2mA-1rj6A:
37.3		 3v2mA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 1.48A 3v2mA-1rj6A:
37.3		 3v2mA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.03A 3v2mA-1rj6A:
37.3		 3v2mA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
 ZN  A 601 ( 3.2A)
ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.43A 3v2mA-1rj6A:
37.3		 3v2mA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 8 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 0.92A 3w6hA-1rj6A:
36.1		 3w6hA-1rj6A:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 8 GLN A  92
HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.46A 3w6hA-1rj6A:
36.1		 3w6hA-1rj6A:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 9 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 0.89A 3w6hB-1rj6A:
36.1		 3w6hB-1rj6A:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 9 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
LEU A 198
THR A 199
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.49A 3w6hB-1rj6A:
36.1		 3w6hB-1rj6A:
35.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.94A 3zncA-1rj6A:
33.6		 3zncA-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.37A 3zncA-1rj6A:
33.6		 3zncA-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 1.48A 3zncA-1rj6A:
33.6		 3zncA-1rj6A:
35.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 7 LEU A 198
GLU A 117
HIS A 119
HIS A  94
 AZM  A 400 (-3.7A)
None
ZN  A 601 ( 3.2A)
ZN  A 601 ( 3.3A)
 1.18A 4aq7A-1rj6A:
undetectable		 4aq7A-1rj6A:
14.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.07A 4coqA-1rj6A:
30.3		 4coqA-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.13A 4coqA-1rj6A:
30.3		 4coqA-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.35A 4coqA-1rj6A:
30.3		 4coqA-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.07A 4coqA-1rj6A:
30.3		 4coqA-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.31A 4coqB-1rj6A:
30.3		 4coqB-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 9 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 1.48A 4coqB-1rj6A:
30.3		 4coqB-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.09A 4coqB-1rj6A:
30.3		 4coqB-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 10 GLN A  92
VAL A 121
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
VAL A 207
TRP A 209
 AZM  A 400 (-4.3A)
AZM  A 400 (-4.8A)
None
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 0.41A 4e3hA-1rj6A:
37.0		 4e3hA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.01A 4g0cA-1rj6A:
37.2		 4g0cA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.37A 4g0cA-1rj6A:
37.2		 4g0cA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.00A 4g0cA-1rj6A:
37.2		 4g0cA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.00A 4g7aA-1rj6A:
30.3		 4g7aA-1rj6A:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.08A 4g7aA-1rj6A:
30.3		 4g7aA-1rj6A:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.41A 4g7aA-1rj6A:
30.3		 4g7aA-1rj6A:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.02A 4g7aA-1rj6A:
30.3		 4g7aA-1rj6A:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.41A 4g7aA-1rj6A:
30.3		 4g7aA-1rj6A:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.99A 4g7aB-1rj6A:
30.1		 4g7aB-1rj6A:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.42A 4g7aB-1rj6A:
30.1		 4g7aB-1rj6A:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.02A 4g7aB-1rj6A:
30.1		 4g7aB-1rj6A:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.10A 4k0sA-1rj6A:
37.2		 4k0sA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.16A 4k0sA-1rj6A:
37.2		 4k0sA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.34A 4k0sA-1rj6A:
37.2		 4k0sA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 ( 4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.60A 4k0sA-1rj6A:
37.2		 4k0sA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 1.49A 4k0sA-1rj6A:
37.2		 4k0sA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.15A 4k0zA-1rj6A:
37.1		 4k0zA-1rj6A:
37.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.17A 4k0zA-1rj6A:
37.1		 4k0zA-1rj6A:
37.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		12 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 ( 4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 0.73A 4k0zA-1rj6A:
37.1		 4k0zA-1rj6A:
37.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 1.42A 4k0zA-1rj6A:
37.1		 4k0zA-1rj6A:
37.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.08A 4k13A-1rj6A:
37.3		 4k13A-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.14A 4k13A-1rj6A:
37.3		 4k13A-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		12 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 131
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 ( 4.8A)
None
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.56A 4k13A-1rj6A:
37.3		 4k13A-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 131
LEU A 141
LEU A 198
THR A 200
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 ( 4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.37A 4k13A-1rj6A:
37.3		 4k13A-1rj6A:
37.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		3 / 3 TYR A 128
ARG A  86
SER A 127
 None
 0.85A 4khpI-1rj6A:
0.0
4khpJ-1rj6A:
0.0		 4khpI-1rj6A:
17.25
4khpJ-1rj6A:
15.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.10A 4lu3A-1rj6A:
43.0		 4lu3A-1rj6A:
82.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 131
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 ( 4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.47A 4lu3A-1rj6A:
43.0		 4lu3A-1rj6A:
82.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 131
LEU A 198
THR A 200
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 ( 4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.47A 4lu3A-1rj6A:
43.0		 4lu3A-1rj6A:
82.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 0.94A 4lu3A-1rj6A:
43.0		 4lu3A-1rj6A:
82.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 0.63A 4m2rA-1rj6A:
37.2		 4m2rA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
PRO A 202
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 1.03A 4m2rA-1rj6A:
37.2		 4m2rA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 1.09A 4m2rA-1rj6A:
37.2		 4m2rA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 HIS A  94
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 601 ( 3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 1.43A 4m2rA-1rj6A:
37.2		 4m2rA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 4 HIS A  64
GLU A 106
HIS A 119
LEU A 141
 None
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
None
 0.42A 4m2rA-1rj6A:
37.2		 4m2rA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 TRP A   5
GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.10A 4m2uA-1rj6A:
37.2		 4m2uA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 TRP A   5
GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.28A 4m2uA-1rj6A:
37.2		 4m2uA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 TRP A   5
HIS A  64
GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.45A 4m2uA-1rj6A:
37.2		 4m2uA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 TRP A   5
HIS A  64
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.10A 4m2uA-1rj6A:
37.2		 4m2uA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 12 TRP A  16
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 200
TRP A 209
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 1.41A 4m2uA-1rj6A:
37.2		 4m2uA-1rj6A:
37.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.05A 4m2vA-1rj6A:
37.2		 4m2vA-1rj6A:
36.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.12A 4m2vA-1rj6A:
37.2		 4m2vA-1rj6A:
36.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.36A 4m2vA-1rj6A:
37.2		 4m2vA-1rj6A:
36.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.05A 4m2wA-1rj6A:
37.3		 4m2wA-1rj6A:
36.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.11A 4m2wA-1rj6A:
37.3		 4m2wA-1rj6A:
36.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.36A 4m2wA-1rj6A:
37.3		 4m2wA-1rj6A:
36.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 8 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.11A 4n16A-1rj6A:
37.4		 4n16A-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 8 GLN A  92
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.40A 4n16A-1rj6A:
37.4		 4n16A-1rj6A:
37.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 ASN A 213
GLN A 188
THR A  35
ILE A 109
PHE A 192
 None
 1.15A 4p6xE-1rj6A:
undetectable		 4p6xE-1rj6A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 ASN A 213
GLN A 188
THR A  35
ILE A 109
PHE A 192
 None
 1.15A 4p6xG-1rj6A:
undetectable		 4p6xG-1rj6A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 ASN A 213
GLN A 188
THR A  35
ILE A 109
PHE A 192
 None
 1.13A 4p6xK-1rj6A:
undetectable		 4p6xK-1rj6A:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.08A 4pxxA-1rj6A:
37.6		 4pxxA-1rj6A:
38.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.41A 4pxxA-1rj6A:
37.6		 4pxxA-1rj6A:
38.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  96
VAL A 121
VAL A 143
THR A 199
TRP A 209
 ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.6A)
None
 0.30A 4twlA-1rj6A:
28.1		 4twlA-1rj6A:
30.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  96
VAL A 121
VAL A 143
THR A 199
TRP A 209
 ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.6A)
None
 0.26A 4twlB-1rj6A:
28.2		 4twlB-1rj6A:
30.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.03A 4uovA-1rj6A:
30.3		 4uovA-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.15A 4uovA-1rj6A:
30.3		 4uovA-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.42A 4uovA-1rj6A:
30.3		 4uovA-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.10A 4uovA-1rj6A:
30.3		 4uovA-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.02A 4uovB-1rj6A:
30.2		 4uovB-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.13A 4uovB-1rj6A:
30.2		 4uovB-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.41A 4uovB-1rj6A:
30.2		 4uovB-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.07A 4uovB-1rj6A:
30.2		 4uovB-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.03A 4uovC-1rj6A:
30.2		 4uovC-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.11A 4uovC-1rj6A:
30.2		 4uovC-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.41A 4uovC-1rj6A:
30.2		 4uovC-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.09A 4uovC-1rj6A:
30.2		 4uovC-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.02A 4uovD-1rj6A:
30.3		 4uovD-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.19A 4uovD-1rj6A:
30.3		 4uovD-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.40A 4uovD-1rj6A:
30.3		 4uovD-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.08A 4uovD-1rj6A:
30.3		 4uovD-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.04A 4uovE-1rj6A:
30.3		 4uovE-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.16A 4uovE-1rj6A:
30.3		 4uovE-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.40A 4uovE-1rj6A:
30.3		 4uovE-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.07A 4uovE-1rj6A:
30.3		 4uovE-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.03A 4uovF-1rj6A:
30.3		 4uovF-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.11A 4uovF-1rj6A:
30.3		 4uovF-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.40A 4uovF-1rj6A:
30.3		 4uovF-1rj6A:
30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.08A 4uovF-1rj6A:
30.3		 4uovF-1rj6A:
30.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.01A 4x5sA-1rj6A:
30.2		 4x5sA-1rj6A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.21A 4x5sA-1rj6A:
30.2		 4x5sA-1rj6A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.43A 4x5sA-1rj6A:
30.2		 4x5sA-1rj6A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.03A 4x5sA-1rj6A:
30.2		 4x5sA-1rj6A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.01A 4x5sB-1rj6A:
30.2		 4x5sB-1rj6A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.18A 4x5sB-1rj6A:
30.2		 4x5sB-1rj6A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.43A 4x5sB-1rj6A:
30.2		 4x5sB-1rj6A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.04A 4x5sB-1rj6A:
30.2		 4x5sB-1rj6A:
29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.12A 4xiwA-1rj6A:
26.3
4xiwH-1rj6A:
26.3		 4xiwA-1rj6A:
29.30
4xiwH-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 200
 None
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.20A 4xiwA-1rj6A:
26.3
4xiwH-1rj6A:
26.3		 4xiwA-1rj6A:
29.30
4xiwH-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.39A 4xiwA-1rj6A:
26.3
4xiwH-1rj6A:
26.3		 4xiwA-1rj6A:
29.30
4xiwH-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.94A 4xiwA-1rj6A:
26.3
4xiwH-1rj6A:
26.3		 4xiwA-1rj6A:
29.30
4xiwH-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.12A 4xiwB-1rj6A:
26.2
4xiwE-1rj6A:
26.6		 4xiwB-1rj6A:
29.30
4xiwE-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.43A 4xiwB-1rj6A:
26.2
4xiwE-1rj6A:
26.6		 4xiwB-1rj6A:
29.30
4xiwE-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.14A 4xiwC-1rj6A:
26.2		 4xiwC-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.43A 4xiwC-1rj6A:
26.2		 4xiwC-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.93A 4xiwC-1rj6A:
26.2		 4xiwC-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.12A 4xiwD-1rj6A:
26.6		 4xiwD-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.44A 4xiwD-1rj6A:
26.6		 4xiwD-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.98A 4xiwD-1rj6A:
26.6		 4xiwD-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.09A 4xiwE-1rj6A:
26.6		 4xiwE-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.26A 4xiwE-1rj6A:
26.6		 4xiwE-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.40A 4xiwE-1rj6A:
26.6		 4xiwE-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.02A 4xiwE-1rj6A:
26.6		 4xiwE-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.05A 4xiwF-1rj6A:
26.4		 4xiwF-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.16A 4xiwF-1rj6A:
26.4		 4xiwF-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.39A 4xiwF-1rj6A:
26.4		 4xiwF-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.00A 4xiwF-1rj6A:
26.4		 4xiwF-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.42A 4xiwF-1rj6A:
26.4		 4xiwF-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.08A 4xiwG-1rj6A:
26.4		 4xiwG-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.29A 4xiwG-1rj6A:
26.4		 4xiwG-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		12 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.39A 4xiwG-1rj6A:
26.4		 4xiwG-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 HIS A  94
HIS A  96
LEU A 141
VAL A 121
LEU A 198
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
None
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.40A 4xiwG-1rj6A:
26.4		 4xiwG-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 HIS A  96
GLU A 106
VAL A 143
LEU A 141
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.18A 4xiwG-1rj6A:
26.4		 4xiwG-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.17A 4xiwH-1rj6A:
26.3		 4xiwH-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.45A 4xiwH-1rj6A:
26.3		 4xiwH-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.01A 4xiwH-1rj6A:
26.3		 4xiwH-1rj6A:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.42A 4ygfA-1rj6A:
26.0		 4ygfA-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.11A 4ygfA-1rj6A:
26.0		 4ygfA-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.42A 4ygfB-1rj6A:
25.7		 4ygfB-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 ( 3.2A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 1.49A 4ygfB-1rj6A:
25.7		 4ygfB-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 0.77A 4ygfB-1rj6A:
25.7		 4ygfB-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.49A 4ygfB-1rj6A:
25.7		 4ygfB-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.35A 4ygfC-1rj6A:
19.2		 4ygfC-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.05A 4ygfC-1rj6A:
19.2		 4ygfC-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.46A 4ygfC-1rj6A:
19.2		 4ygfC-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.31A 4ygfD-1rj6A:
25.1		 4ygfD-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.04A 4ygfD-1rj6A:
25.1		 4ygfD-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 12 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.39A 4ygfE-1rj6A:
26.1		 4ygfE-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 0.81A 4ygfE-1rj6A:
26.1		 4ygfE-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.30A 4ygfF-1rj6A:
25.8		 4ygfF-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.48A 4ygfF-1rj6A:
25.8		 4ygfF-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.32A 4ygfG-1rj6A:
25.9		 4ygfG-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.46A 4ygfG-1rj6A:
25.9		 4ygfG-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.32A 4ygfH-1rj6A:
25.9		 4ygfH-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.43A 4ygfH-1rj6A:
25.9		 4ygfH-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.51A 4yhaA-1rj6A:
25.9		 4yhaA-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 0.57A 4yhaB-1rj6A:
25.0		 4yhaB-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.41A 4yhaC-1rj6A:
26.1		 4yhaC-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.47A 4yhaC-1rj6A:
26.1		 4yhaC-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.45A 4yhaD-1rj6A:
24.9		 4yhaD-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.06A 4yhaD-1rj6A:
24.9		 4yhaD-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
PRO A 202
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
None
 0.54A 4yhaE-1rj6A:
26.2		 4yhaE-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 HIS A  94
HIS A 119
LEU A 198
THR A 199
PRO A 201
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
None
 1.49A 4yhaE-1rj6A:
26.2		 4yhaE-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.64A 4yhaF-1rj6A:
23.4		 4yhaF-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.42A 4yhaG-1rj6A:
25.7		 4yhaG-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.50A 4yhaG-1rj6A:
25.7		 4yhaG-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 10 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.43A 4yhaH-1rj6A:
25.6		 4yhaH-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 11 LEU A 241
VAL A 242
ASN A 244
GLY A 104
LEU A 226
 None
 1.00A 4zbqA-1rj6A:
undetectable		 4zbqA-1rj6A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 4 VAL A 211
ILE A  31
ASN A 110
VAL A  38
 None
 1.20A 5ajqA-1rj6A:
undetectable		 5ajqA-1rj6A:
22.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
PRO A 202
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.98A 5c8iA-1rj6A:
37.3		 5c8iA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 None
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 1.09A 5c8iA-1rj6A:
37.3		 5c8iA-1rj6A:
37.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 0.46A 5c8iA-1rj6A:
37.3		 5c8iA-1rj6A:
37.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 5 LEU A  95
ALA A 116
LEU A 118
VAL A 150
 None
 1.19A 5cr1A-1rj6A:
undetectable		 5cr1A-1rj6A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 5 ILE A 167
LEU A  95
HIS A 159
VAL A 176
 None
 1.24A 5jmnB-1rj6A:
undetectable		 5jmnB-1rj6A:
13.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.16A 5jn8A-1rj6A:
33.9		 5jn8A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.37A 5jn8A-1rj6A:
33.9		 5jn8A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.05A 5jn8A-1rj6A:
33.9		 5jn8A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
VAL A 121
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.23A 5jn8B-1rj6A:
34.1		 5jn8B-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.41A 5jn8B-1rj6A:
34.1		 5jn8B-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 HIS A  94
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.13A 5jn8B-1rj6A:
34.1		 5jn8B-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.10A 5jn8C-1rj6A:
33.8		 5jn8C-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.43A 5jn8C-1rj6A:
33.8		 5jn8C-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.17A 5jn8C-1rj6A:
33.8		 5jn8C-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 10 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.07A 5jn8D-1rj6A:
33.4		 5jn8D-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.42A 5jn8D-1rj6A:
33.4		 5jn8D-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.08A 5jn8D-1rj6A:
33.4		 5jn8D-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.11A 5jn9A-1rj6A:
33.8		 5jn9A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.31A 5jn9A-1rj6A:
33.8		 5jn9A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.36A 5jn9A-1rj6A:
33.8		 5jn9A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.15A 5jn9A-1rj6A:
33.8		 5jn9A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.07A 5jn9B-1rj6A:
34.2		 5jn9B-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.27A 5jn9B-1rj6A:
34.2		 5jn9B-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.31A 5jn9B-1rj6A:
34.2		 5jn9B-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.06A 5jn9B-1rj6A:
34.2		 5jn9B-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 9 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.10A 5jn9C-1rj6A:
33.8		 5jn9C-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.37A 5jn9C-1rj6A:
33.8		 5jn9C-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 9 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.38A 5jn9C-1rj6A:
33.8		 5jn9C-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.10A 5jn9C-1rj6A:
33.8		 5jn9C-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
 ZN  A 601 ( 3.2A)
ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.49A 5jn9C-1rj6A:
33.8		 5jn9C-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.12A 5jn9D-1rj6A:
33.4		 5jn9D-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.18A 5jn9D-1rj6A:
33.4		 5jn9D-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.38A 5jn9D-1rj6A:
33.4		 5jn9D-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.41A 5jn9D-1rj6A:
33.4		 5jn9D-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
 None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.61A 5jnaA-1rj6A:
33.8		 5jnaA-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
HIS A 119
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.97A 5jnaA-1rj6A:
33.8		 5jnaA-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
VAL A 121
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.6A)
 1.05A 5jnaA-1rj6A:
33.8		 5jnaA-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.34A 5jnaA-1rj6A:
33.8		 5jnaA-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 12 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.08A 5jnaA-1rj6A:
33.8		 5jnaA-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.09A 5jnaA-1rj6A:
33.8		 5jnaA-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.58A 5jnaB-1rj6A:
34.1		 5jnaB-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.99A 5jnaB-1rj6A:
34.1		 5jnaB-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.14A 5jnaB-1rj6A:
34.1		 5jnaB-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.06A 5jnaB-1rj6A:
34.1		 5jnaB-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 11 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
 None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.60A 5jnaC-1rj6A:
33.8		 5jnaC-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.00A 5jnaC-1rj6A:
33.8		 5jnaC-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.11A 5jnaC-1rj6A:
33.8		 5jnaC-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.32A 5jnaC-1rj6A:
33.8		 5jnaC-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 11 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.05A 5jnaC-1rj6A:
33.8		 5jnaC-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.59A 5jnaD-1rj6A:
33.3		 5jnaD-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.01A 5jnaD-1rj6A:
33.3		 5jnaD-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.11A 5jnaD-1rj6A:
33.3		 5jnaD-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.03A 5jnaD-1rj6A:
33.3		 5jnaD-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
VAL A 121
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.24A 5jncA-1rj6A:
33.8		 5jncA-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.39A 5jncA-1rj6A:
33.8		 5jncA-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 11 HIS A  94
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 4.5A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.14A 5jncA-1rj6A:
33.8		 5jncA-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.13A 5jncB-1rj6A:
34.2		 5jncB-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.20A 5jncB-1rj6A:
34.2		 5jncB-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.35A 5jncB-1rj6A:
34.2		 5jncB-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.42A 5jncB-1rj6A:
34.2		 5jncB-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 9 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.09A 5jncC-1rj6A:
33.8		 5jncC-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.37A 5jncC-1rj6A:
33.8		 5jncC-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.12A 5jncC-1rj6A:
33.8		 5jncC-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 9 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.11A 5jncD-1rj6A:
33.4		 5jncD-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.39A 5jncD-1rj6A:
33.4		 5jncD-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.12A 5jncD-1rj6A:
33.4		 5jncD-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
VAL A 121
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.19A 5ku6A-1rj6A:
33.8		 5ku6A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.39A 5ku6A-1rj6A:
33.8		 5ku6A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.06A 5ku6A-1rj6A:
33.8		 5ku6A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.44A 5ku6A-1rj6A:
33.8		 5ku6A-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.10A 5ku6B-1rj6A:
34.2		 5ku6B-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.23A 5ku6B-1rj6A:
34.2		 5ku6B-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.38A 5ku6B-1rj6A:
34.2		 5ku6B-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.43A 5ku6B-1rj6A:
34.2		 5ku6B-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.12A 5ku6C-1rj6A:
33.9		 5ku6C-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.40A 5ku6C-1rj6A:
33.9		 5ku6C-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.16A 5ku6C-1rj6A:
33.9		 5ku6C-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.11A 5ku6D-1rj6A:
33.4		 5ku6D-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.39A 5ku6D-1rj6A:
33.4		 5ku6D-1rj6A:
35.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 601 (-3.3A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.13A 5ku6D-1rj6A:
33.4		 5ku6D-1rj6A:
35.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 7 GLN A  67
HIS A  94
LEU A 198
THR A 199
THR A 200
 None
ZN  A 601 ( 3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.20A 5m78A-1rj6A:
37.2		 5m78A-1rj6A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 7 GLN A  92
HIS A  94
VAL A 121
LEU A 198
THR A 199
THR A 200
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 0.36A 5m78A-1rj6A:
37.2		 5m78A-1rj6A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 7 GLN A  92
HIS A  94
VAL A 121
LEU A 198
THR A 200
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.30A 5m78A-1rj6A:
37.2		 5m78A-1rj6A:
14.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 6 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 ( 3.2A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.26A 5ogjA-1rj6A:
36.8		 5ogjA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 6 HIS A  94
HIS A  96
LEU A 198
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.21A 5ogjB-1rj6A:
36.4		 5ogjB-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 6 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 ( 3.2A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.24A 5ogjB-1rj6A:
36.4		 5ogjB-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 5 HIS A  94
HIS A  96
LEU A 198
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.22A 5ohhA-1rj6A:
36.6		 5ohhA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 5 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
 ZN  A 601 ( 3.3A)
ZN  A 601 ( 3.2A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 0.23A 5ohhA-1rj6A:
36.6		 5ohhA-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		4 / 6 HIS A  94
HIS A  96
LEU A 198
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.21A 5ohhB-1rj6A:
36.7		 5ohhB-1rj6A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 6 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 ( 3.2A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.24A 5ohhB-1rj6A:
36.7		 5ohhB-1rj6A:
36.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 HIS A  94
HIS A  96
HIS A 119
THR A 199
PRO A 201
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-3.6A)
None
None
 1.33A 5tt3A-1rj6A:
25.8		 5tt3A-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
PRO A 202
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
None
 0.53A 5tt3A-1rj6A:
25.8		 5tt3A-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 10 HIS A  94
HIS A  96
VAL A 121
LEU A 198
PRO A 202
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
None
 1.05A 5tt3A-1rj6A:
25.8		 5tt3A-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.38A 5tt3B-1rj6A:
24.2		 5tt3B-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.15A 5tt3B-1rj6A:
24.2		 5tt3B-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.49A 5tt3B-1rj6A:
24.2		 5tt3B-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.33A 5tt3B-1rj6A:
24.2		 5tt3B-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
PRO A 202
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
None
 0.47A 5tt3C-1rj6A:
26.1		 5tt3C-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 10 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
PRO A 202
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.99A 5tt3C-1rj6A:
26.1		 5tt3C-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.42A 5tt3E-1rj6A:
26.0		 5tt3E-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  96
HIS A 119
VAL A 143
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.07A 5tt3E-1rj6A:
26.0		 5tt3E-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
 1.14A 5tt3F-1rj6A:
25.1		 5tt3F-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.48A 5tt3F-1rj6A:
25.1		 5tt3F-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 8 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.47A 5tt3F-1rj6A:
25.1		 5tt3F-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 8 HIS A  94
HIS A 119
VAL A 143
LEU A 198
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 ( 3.2A)
None
AZM  A 400 (-3.7A)
None
 1.48A 5tt3F-1rj6A:
25.1		 5tt3F-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.43A 5tt3G-1rj6A:
25.1		 5tt3G-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.40A 5tt3G-1rj6A:
25.1		 5tt3G-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 9 HIS A  96
HIS A 119
VAL A 143
LEU A 198
THR A 199
 ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
 1.07A 5tt3G-1rj6A:
25.1		 5tt3G-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
TRP A 209
 ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
ZN  A 601 ( 3.2A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
None
 0.48A 5tt3H-1rj6A:
25.4		 5tt3H-1rj6A:
28.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 GLN A  67
HIS A  94
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
ZN  A 601 ( 3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 1.22A 6bbsA-1rj6A:
30.4		 6bbsA-1rj6A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 12 TRP A   5
ASN A  62
HIS A  64
GLN A  92
HIS A  94
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
None
None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.78A 6bbsA-1rj6A:
30.4		 6bbsA-1rj6A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		9 / 12 TRP A   5
HIS A  64
GLN A  92
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 0.56A 6bbsA-1rj6A:
30.4		 6bbsA-1rj6A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		11 / 12 TRP A   5
ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 None
None
AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 0.66A 6bc9A-1rj6A:
37.1		 6bc9A-1rj6A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 TRP A   5
GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
 1.10A 6bc9A-1rj6A:
37.1		 6bc9A-1rj6A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 TRP A   5
HIS A  94
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 None
ZN  A 601 ( 3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 1.39A 6bc9A-1rj6A:
37.1		 6bc9A-1rj6A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		5 / 5 HIS A  64
GLU A 106
HIS A 119
LEU A 141
VAL A 143
 None
ZN  A 601 ( 4.5A)
ZN  A 601 ( 3.2A)
None
None
 0.38A 6bc9A-1rj6A:
37.1		 6bc9A-1rj6A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
PRO A 202
 None
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 1.04A 6bccA-1rj6A:
37.2		 6bccA-1rj6A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		7 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 None
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
 1.10A 6bccA-1rj6A:
37.2		 6bccA-1rj6A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 AZM  A 400 (-4.3A)
ZN  A 601 ( 3.3A)
ZN  A 601 (-3.3A)
AZM  A 400 (-4.8A)
None
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 0.42A 6bccA-1rj6A:
37.2		 6bccA-1rj6A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 1rj6 CARBONIC ANHYDRASE
XIV
(Mus
musculus) 		6 / 12 HIS A  94
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 601 ( 3.3A)
AZM  A 400 (-3.7A)
AZM  A 400 (-3.6A)
AZM  A 400 (-3.6A)
None
None
 1.44A 6bccA-1rj6A:
37.2		 6bccA-1rj6A:
15.42