SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 7 LEU A 253
GLN A 254
LEU A 293
PHE A 284
 None
 1.03A 1v55P-1rj7A:
undetectable
1v55W-1rj7A:
undetectable		 1v55P-1rj7A:
19.93
1v55W-1rj7A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 7 LEU A 253
GLN A 254
PHE A 379
PHE A 284
 None
 0.90A 1v55P-1rj7A:
undetectable
1v55W-1rj7A:
undetectable		 1v55P-1rj7A:
19.93
1v55W-1rj7A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 7 LEU A 253
GLN A 254
LEU A 293
PHE A 284
 None
 0.90A 2dysC-1rj7A:
undetectable
2dysJ-1rj7A:
undetectable		 2dysC-1rj7A:
19.93
2dysJ-1rj7A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 7 LEU A 253
GLN A 254
PHE A 379
PHE A 284
 None
 0.88A 2dysC-1rj7A:
undetectable
2dysJ-1rj7A:
undetectable		 2dysC-1rj7A:
19.93
2dysJ-1rj7A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 7 LEU A 253
GLN A 254
PHE A 379
PHE A 284
 None
 0.93A 2eijP-1rj7A:
undetectable
2eijW-1rj7A:
undetectable		 2eijP-1rj7A:
19.93
2eijW-1rj7A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 7 LEU A 253
GLN A 254
LEU A 293
PHE A 284
 None
 0.94A 2zxwC-1rj7A:
undetectable
2zxwJ-1rj7A:
undetectable		 2zxwC-1rj7A:
19.93
2zxwJ-1rj7A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 7 LEU A 253
GLN A 254
PHE A 379
PHE A 284
 None
 0.87A 2zxwC-1rj7A:
undetectable
2zxwJ-1rj7A:
undetectable		 2zxwC-1rj7A:
19.93
2zxwJ-1rj7A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 6 LEU A 253
GLN A 254
PHE A 379
PHE A 284
 None
 0.89A 2zxwP-1rj7A:
undetectable
2zxwW-1rj7A:
undetectable		 2zxwP-1rj7A:
19.93
2zxwW-1rj7A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 6 LEU A 253
GLN A 254
LEU A 293
PHE A 284
 None
 0.87A 3ag1C-1rj7A:
undetectable
3ag1J-1rj7A:
undetectable		 3ag1C-1rj7A:
19.93
3ag1J-1rj7A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 6 LEU A 253
GLN A 254
PHE A 379
PHE A 284
 None
 0.73A 3ag1C-1rj7A:
undetectable
3ag1J-1rj7A:
undetectable		 3ag1C-1rj7A:
19.93
3ag1J-1rj7A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		5 / 10 ALA A 318
ILE A 369
ILE A 260
LEU A 271
ILE A 371
 None
 1.20A 4dtaA-1rj7A:
undetectable		 4dtaA-1rj7A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 5 ILE A 369
VAL A 309
PHE A 379
HIS A 366
 None
 1.35A 4rzvA-1rj7A:
0.0		 4rzvA-1rj7A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		3 / 3 VAL A 351
ALA A 349
PHE A 329
 None
 0.89A 4w5nA-1rj7A:
undetectable		 4w5nA-1rj7A:
11.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 7 LEU A 253
GLN A 254
LEU A 293
PHE A 284
 None
 0.95A 5z84C-1rj7A:
undetectable
5z84J-1rj7A:
undetectable		 5z84C-1rj7A:
19.93
5z84J-1rj7A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 7 LEU A 253
GLN A 254
PHE A 379
PHE A 284
 None
 0.90A 5z84C-1rj7A:
undetectable
5z84J-1rj7A:
undetectable		 5z84C-1rj7A:
19.93
5z84J-1rj7A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1rj7 ECTODYSPLASIN A
(Homo
sapiens) 		4 / 5 LEU A 253
GLN A 254
PHE A 379
PHE A 284
 None
 0.91A 6nmpP-1rj7A:
undetectable
6nmpW-1rj7A:
undetectable		 6nmpP-1rj7A:
19.93
6nmpW-1rj7A:
15.65