SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rjl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1rjl OUTER SURFACE
PROTEIN B
(Borreliella
burgdorferi) 		5 / 11 VAL C 224
PHE C 260
ILE C 205
ILE C 248
LEU C 246
 None
 1.00A 1z11A-1rjlC:
0.0		 1z11A-1rjlC:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1rjl OUTER SURFACE
PROTEIN B
(Borreliella
burgdorferi) 		5 / 11 VAL C 224
PHE C 260
ILE C 205
ILE C 248
LEU C 246
 None
 1.07A 1z11B-1rjlC:
undetectable		 1z11B-1rjlC:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 1rjl OUTER SURFACE
PROTEIN B
(Borreliella
burgdorferi) 		4 / 8 ILE C 285
PHE C 260
LEU C 295
LEU C 212
 None
 0.90A 2w98B-1rjlC:
undetectable		 2w98B-1rjlC:
16.42