SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rk2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 9 ALA A 209
GLU A 214
VAL A 220
GLY A 235
GLY A 237
 None
 1.17A 1bcuH-1rk2A:
undetectable		 1bcuH-1rk2A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.35A 1bx4A-1rk2A:
32.4		 1bx4A-1rk2A:
28.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 THR A 223
GLY A 225
ALA A 253
GLY A 254
HIS A 279
ALA A 282
 ADP  A 310 (-3.4A)
ADP  A 310 (-3.7A)
ADP  A 310 (-3.5A)
ADP  A 310 (-3.3A)
ADP  A 310 (-3.6A)
ADP  A 310 (-3.3A)
 0.44A 1bx4A-1rk2A:
32.4		 1bx4A-1rk2A:
28.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		4 / 7 LEU A 177
VAL A 149
MET A 150
LEU A 138
 None
 0.73A 1hk3A-1rk2A:
undetectable		 1hk3A-1rk2A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ILE A 112
HIS A  17
GLY A  42
GLU A 143
ILE A 251
 None
None
RIB  A 311 (-3.4A)
RIB  A 311 (-2.5A)
None
 1.24A 1kyvB-1rk2A:
4.1
1kyvC-1rk2A:
undetectable		 1kyvB-1rk2A:
19.74
1kyvC-1rk2A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.30A 1liiA-1rk2A:
33.4		 1liiA-1rk2A:
26.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.42A 1likA-1rk2A:
32.9		 1likA-1rk2A:
26.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 10 THR A 223
GLY A 225
VAL A 229
ALA A 253
ALA A 282
 ADP  A 310 (-3.4A)
ADP  A 310 (-3.7A)
None
ADP  A 310 (-3.5A)
ADP  A 310 (-3.3A)
 0.44A 1likA-1rk2A:
32.9		 1likA-1rk2A:
26.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		3 / 3 ARG A 227
ILE A 222
TRP A 230
 None
 1.09A 1m8eB-1rk2A:
undetectable		 1m8eB-1rk2A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 1rk2 RIBOKINASE
(Escherichia
coli) 		4 / 8 ILE A 301
LEU A 305
PHE A 243
GLY A 242
 None
 1.07A 1os6A-1rk2A:
undetectable		 1os6A-1rk2A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ILE A 184
ILE A 197
VAL A 211
VAL A 220
ILE A 222
 None
 0.88A 1r5lA-1rk2A:
undetectable		 1r5lA-1rk2A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ALA A  98
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.6A)
RIB  A 311 (-3.1A)
 0.33A 2c49A-1rk2A:
37.0		 2c49A-1rk2A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 1rk2 RIBOKINASE
(Escherichia
coli) 		4 / 7 ASP A  16
GLY A  41
GLY A  42
ASN A  46
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
 0.41A 2c49B-1rk2A:
34.5		 2c49B-1rk2A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 9 GLY A  44
ASN A  14
ILE A  13
ALA A  62
VAL A  87
 None
RIB  A 311 (-4.1A)
None
None
None
 1.22A 2drdA-1rk2A:
undetectable		 2drdA-1rk2A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
ASN A  46
ALA A 168
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 1.04A 2pkkA-1rk2A:
34.8		 2pkkA-1rk2A:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 SER A  12
ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 None
RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.51A 2pkkA-1rk2A:
34.8		 2pkkA-1rk2A:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 SER A  12
ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 None
RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.52A 2pkmA-1rk2A:
34.6		 2pkmA-1rk2A:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 11 ALA A  15
GLY A 115
HIS A 113
ASP A  67
ILE A  69
 None
 0.99A 2x1lA-1rk2A:
undetectable		 2x1lA-1rk2A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ALA A  15
GLY A 115
HIS A 113
ASP A  67
ILE A  69
 None
 1.01A 2x1lB-1rk2A:
undetectable		 2x1lB-1rk2A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 11 ALA A  15
GLY A 115
HIS A 113
ASP A  67
ILE A  69
 None
 1.01A 2x1lC-1rk2A:
undetectable		 2x1lC-1rk2A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 8 SER A  12
PHE A 257
GLY A 259
ASN A  46
ALA A 282
 None
ADP  A 310 ( 4.4A)
None
RIB  A 311 (-3.3A)
ADP  A 310 (-3.3A)
 1.46A 3aodA-1rk2A:
undetectable		 3aodA-1rk2A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 8 VAL A  87
GLY A  65
THR A  64
GLY A 115
ALA A 116
 None
 1.38A 3aruA-1rk2A:
undetectable		 3aruA-1rk2A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		3 / 3 ARG A 227
ILE A 222
TRP A 230
 None
 1.04A 3e68A-1rk2A:
undetectable		 3e68A-1rk2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		3 / 3 ARG A 227
ILE A 222
TRP A 230
 None
 1.09A 3e6tB-1rk2A:
undetectable		 3e6tB-1rk2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		3 / 3 ARG A 227
ILE A 222
TRP A 230
 None
 1.16A 3e7iB-1rk2A:
undetectable		 3e7iB-1rk2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 1rk2 RIBOKINASE
(Escherichia
coli) 		4 / 4 GLU A  71
GLY A  65
THR A  95
GLU A  93
 None
 1.12A 3e9xA-1rk2A:
0.0		 3e9xA-1rk2A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 VAL A 199
ALA A 208
LEU A 177
LEU A 178
ILE A 184
 None
 0.81A 3hegA-1rk2A:
undetectable		 3hegA-1rk2A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ILE A 162
VAL A 163
ALA A 137
LEU A 138
PRO A 167
 None
 0.98A 3mb5A-1rk2A:
4.1		 3mb5A-1rk2A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		3 / 3 ASP A  80
GLU A 300
SER A  72
 None
 0.74A 3p2kA-1rk2A:
4.2		 3p2kA-1rk2A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.30A 3uboA-1rk2A:
34.8		 3uboA-1rk2A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.85A 3uboA-1rk2A:
34.8		 3uboA-1rk2A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.31A 3uboB-1rk2A:
35.8		 3uboB-1rk2A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.82A 3uboB-1rk2A:
35.8		 3uboB-1rk2A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.35A 3uq6A-1rk2A:
33.4		 3uq6A-1rk2A:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.42A 3vaqA-1rk2A:
33.0		 3vaqA-1rk2A:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.34A 3vasA-1rk2A:
33.0		 3vasA-1rk2A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASN A  46
ILE A  82
GLY A 259
VAL A   9
GLY A  55
 RIB  A 311 (-3.3A)
None
None
None
None
 0.91A 3vasB-1rk2A:
23.4		 3vasB-1rk2A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.31A 3vasB-1rk2A:
23.4		 3vasB-1rk2A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 VAL A 240
ILE A 162
ILE A 183
LEU A 221
VAL A 229
 None
 0.98A 3w68C-1rk2A:
undetectable		 3w68C-1rk2A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 VAL A 240
ILE A 162
ILE A 183
LEU A 221
VAL A 229
 None
 0.97A 3w68D-1rk2A:
undetectable		 3w68D-1rk2A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 9 ASN A  46
GLY A  42
GLY A  41
GLY A  44
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 1.03A 3ztvA-1rk2A:
undetectable		 3ztvA-1rk2A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 PRO A 186
LEU A 194
LEU A 173
LEU A 177
ILE A 217
 None
 1.08A 4a7aB-1rk2A:
3.2		 4a7aB-1rk2A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.39A 4dc3B-1rk2A:
33.0		 4dc3B-1rk2A:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.29A 4e3aA-1rk2A:
35.5		 4e3aA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4e3aA-1rk2A:
35.5		 4e3aA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.28A 4e3aB-1rk2A:
35.3		 4e3aB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4e3aB-1rk2A:
35.3		 4e3aB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 LEU A 305
ILE A 301
ALA A 274
GLY A 254
ALA A 280
 None
None
None
ADP  A 310 (-3.3A)
None
 0.91A 4enhA-1rk2A:
0.0		 4enhA-1rk2A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.35A 4jksA-1rk2A:
35.6		 4jksA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4jksA-1rk2A:
35.6		 4jksA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.78A 4jksA-1rk2A:
35.6		 4jksA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.34A 4jksB-1rk2A:
35.6		 4jksB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4jksB-1rk2A:
35.6		 4jksB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.78A 4jksB-1rk2A:
35.6		 4jksB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  18
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
 0.98A 4jkuA-1rk2A:
35.6		 4jkuA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.34A 4jkuA-1rk2A:
35.6		 4jkuA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4jkuA-1rk2A:
35.6		 4jkuA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A  18
GLU A 143
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-2.5A)
 0.85A 4jkuA-1rk2A:
35.6		 4jkuA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.77A 4jkuA-1rk2A:
35.6		 4jkuA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.25A 4jkuB-1rk2A:
35.6		 4jkuB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.82A 4jkuB-1rk2A:
35.6		 4jkuB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  18
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
 0.99A 4k8cA-1rk2A:
35.6		 4k8cA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.32A 4k8cA-1rk2A:
35.6		 4k8cA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4k8cA-1rk2A:
35.6		 4k8cA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A  18
GLU A 143
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-2.5A)
 0.83A 4k8cA-1rk2A:
35.6		 4k8cA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.79A 4k8cA-1rk2A:
35.6		 4k8cA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.32A 4k8cB-1rk2A:
35.5		 4k8cB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4k8cB-1rk2A:
35.5		 4k8cB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.77A 4k8cB-1rk2A:
35.5		 4k8cB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.36A 4k8kA-1rk2A:
35.5		 4k8kA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4k8kA-1rk2A:
35.5		 4k8kA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.78A 4k8kA-1rk2A:
35.5		 4k8kA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.35A 4k8kB-1rk2A:
35.6		 4k8kB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.82A 4k8kB-1rk2A:
35.6		 4k8kB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.77A 4k8kB-1rk2A:
35.6		 4k8kB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.27A 4k8pA-1rk2A:
35.6		 4k8pA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.79A 4k8pA-1rk2A:
35.6		 4k8pA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.27A 4k8pB-1rk2A:
35.5		 4k8pB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.79A 4k8pB-1rk2A:
35.5		 4k8pB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.30A 4k8tA-1rk2A:
35.5		 4k8tA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4k8tA-1rk2A:
35.5		 4k8tA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.31A 4k8tB-1rk2A:
35.5		 4k8tB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4k8tB-1rk2A:
35.5		 4k8tB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.27A 4k93A-1rk2A:
35.7		 4k93A-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4k93A-1rk2A:
35.7		 4k93A-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.27A 4k93B-1rk2A:
35.7		 4k93B-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4k93B-1rk2A:
35.7		 4k93B-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.27A 4k9cA-1rk2A:
35.7		 4k9cA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4k9cA-1rk2A:
35.7		 4k9cA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.27A 4k9cB-1rk2A:
35.6		 4k9cB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4k9cB-1rk2A:
35.6		 4k9cB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.29A 4k9iA-1rk2A:
35.5		 4k9iA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4k9iA-1rk2A:
35.5		 4k9iA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.29A 4k9iB-1rk2A:
35.6		 4k9iB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.79A 4k9iB-1rk2A:
35.6		 4k9iB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.28A 4kadA-1rk2A:
35.6		 4kadA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4kadA-1rk2A:
35.6		 4kadA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.27A 4kadB-1rk2A:
32.4		 4kadB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4kadB-1rk2A:
32.4		 4kadB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.34A 4kahA-1rk2A:
35.7		 4kahA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4kahA-1rk2A:
35.7		 4kahA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.79A 4kahA-1rk2A:
35.7		 4kahA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.34A 4kahB-1rk2A:
35.7		 4kahB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.79A 4kahB-1rk2A:
35.7		 4kahB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.79A 4kahB-1rk2A:
35.7		 4kahB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  18
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
 0.97A 4kalA-1rk2A:
35.6		 4kalA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.34A 4kalA-1rk2A:
35.6		 4kalA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4kalA-1rk2A:
35.6		 4kalA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A  18
GLU A 143
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-2.5A)
 0.83A 4kalA-1rk2A:
35.6		 4kalA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.79A 4kalA-1rk2A:
35.6		 4kalA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A  18
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
 0.97A 4kalB-1rk2A:
35.6		 4kalB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.36A 4kalB-1rk2A:
35.6		 4kalB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4kalB-1rk2A:
35.6		 4kalB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A  18
GLU A 143
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-2.5A)
 0.84A 4kalB-1rk2A:
35.6		 4kalB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.79A 4kalB-1rk2A:
35.6		 4kalB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.34A 4kanA-1rk2A:
35.7		 4kanA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4kanA-1rk2A:
35.7		 4kanA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.78A 4kanA-1rk2A:
35.7		 4kanA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.34A 4kanB-1rk2A:
35.7		 4kanB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4kanB-1rk2A:
35.7		 4kanB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.79A 4kanB-1rk2A:
35.7		 4kanB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.35A 4kbeA-1rk2A:
35.6		 4kbeA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4kbeA-1rk2A:
35.6		 4kbeA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.79A 4kbeA-1rk2A:
35.6		 4kbeA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.33A 4kbeB-1rk2A:
35.6		 4kbeB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4kbeB-1rk2A:
35.6		 4kbeB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.80A 4kbeB-1rk2A:
35.6		 4kbeB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.35A 4lbgA-1rk2A:
35.5		 4lbgA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4lbgA-1rk2A:
35.5		 4lbgA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.77A 4lbgA-1rk2A:
35.5		 4lbgA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.33A 4lbgB-1rk2A:
35.6		 4lbgB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4lbgB-1rk2A:
35.6		 4lbgB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.78A 4lbgB-1rk2A:
35.6		 4lbgB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.31A 4lbxA-1rk2A:
35.7		 4lbxA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4lbxA-1rk2A:
35.7		 4lbxA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.29A 4lbxB-1rk2A:
35.6		 4lbxB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4lbxB-1rk2A:
35.6		 4lbxB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.28A 4lc4A-1rk2A:
35.6		 4lc4A-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4lc4A-1rk2A:
35.6		 4lc4A-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.29A 4lc4B-1rk2A:
35.4		 4lc4B-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.82A 4lc4B-1rk2A:
35.4		 4lc4B-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.34A 4lcaA-1rk2A:
35.7		 4lcaA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.80A 4lcaA-1rk2A:
35.7		 4lcaA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.80A 4lcaA-1rk2A:
35.7		 4lcaA-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ILE A 100
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 0.34A 4lcaB-1rk2A:
35.5		 4lcaB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
GLU A 143
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.5A)
RIB  A 311 (-3.1A)
 0.81A 4lcaB-1rk2A:
35.5		 4lcaB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 GLY A  41
GLY A  42
ASN A  46
ILE A 110
ASP A 255
 RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 ( 4.6A)
RIB  A 311 (-3.1A)
 0.78A 4lcaB-1rk2A:
35.5		 4lcaB-1rk2A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.33A 4n09B-1rk2A:
33.4		 4n09B-1rk2A:
26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.35A 4n09C-1rk2A:
33.6		 4n09C-1rk2A:
26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.35A 4n09D-1rk2A:
33.3		 4n09D-1rk2A:
26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 LEU A   7
ALA A  51
ALA A 164
ALA A 137
ILE A 183
 None
 0.95A 4o2bD-1rk2A:
5.1		 4o2bD-1rk2A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 LEU A   7
ALA A  56
ALA A 164
ILE A 162
ALA A 137
ILE A 183
 None
 1.39A 4o2bD-1rk2A:
5.1		 4o2bD-1rk2A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
ASN A  46
ALA A 168
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.3A)
None
RIB  A 311 (-3.1A)
 1.05A 4ubeA-1rk2A:
34.7		 4ubeA-1rk2A:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 SER A  12
ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 None
RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.52A 4ubeA-1rk2A:
34.7		 4ubeA-1rk2A:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ILE A  13
SER A  12
GLY A  44
ALA A  45
GLU A 143
 None
None
None
None
RIB  A 311 (-2.5A)
 1.20A 4xt8A-1rk2A:
undetectable		 4xt8A-1rk2A:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1rk2 RIBOKINASE
(Escherichia
coli) 		4 / 7 LEU A 261
ALA A 274
LEU A 265
LEU A 221
 None
 0.68A 4z90F-1rk2A:
undetectable
4z90G-1rk2A:
undetectable
4z90H-1rk2A:
undetectable
4z90J-1rk2A:
undetectable		 4z90F-1rk2A:
22.87
4z90G-1rk2A:
22.87
4z90H-1rk2A:
22.87
4z90J-1rk2A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 8 PRO A 145
VAL A 149
ALA A  62
GLY A  11
MET A 140
 None
 1.34A 4zjzB-1rk2A:
2.8		 4zjzB-1rk2A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ALA A  62
LEU A 124
ALA A  45
GLY A  11
SER A 144
 None
 1.41A 5jglA-1rk2A:
3.0		 5jglA-1rk2A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 6 GLY A  96
THR A  95
SER A  94
GLY A  65
ASN A 117
 None
 1.18A 5k4pA-1rk2A:
undetectable		 5k4pA-1rk2A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ASP A  16
GLY A  41
GLY A  42
ASN A  46
ASP A 255
 RIB  A 311 (-2.8A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.4A)
RIB  A 311 (-3.3A)
RIB  A 311 (-3.1A)
 0.33A 5kb5A-1rk2A:
33.9		 5kb5A-1rk2A:
28.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 THR A 223
GLY A 225
ALA A 253
GLY A 254
HIS A 279
ALA A 282
 ADP  A 310 (-3.4A)
ADP  A 310 (-3.7A)
ADP  A 310 (-3.5A)
ADP  A 310 (-3.3A)
ADP  A 310 (-3.6A)
ADP  A 310 (-3.3A)
 0.36A 5kb6A-1rk2A:
30.8		 5kb6A-1rk2A:
28.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		6 / 12 THR A 223
GLY A 225
ALA A 253
GLY A 254
HIS A 279
ALA A 282
 ADP  A 310 (-3.4A)
ADP  A 310 (-3.7A)
ADP  A 310 (-3.5A)
ADP  A 310 (-3.3A)
ADP  A 310 (-3.6A)
ADP  A 310 (-3.3A)
 0.35A 5kb6B-1rk2A:
30.9		 5kb6B-1rk2A:
28.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 VAL A  87
ALA A 118
GLY A  44
ALA A  45
LEU A  77
 None
 1.07A 5kirB-1rk2A:
undetectable		 5kirB-1rk2A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 VAL A 199
LEU A 212
ALA A 191
ARG A 227
GLY A 228
 None
None
None
None
ADP  A 310 (-4.3A)
 1.21A 5m5cB-1rk2A:
4.9		 5m5cB-1rk2A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ILE A 184
ILE A 197
VAL A 211
VAL A 220
ILE A 222
 None
 0.88A 5mueA-1rk2A:
undetectable		 5mueA-1rk2A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 ILE A 184
ILE A 197
VAL A 211
VAL A 220
ILE A 222
 None
 0.83A 5mugA-1rk2A:
undetectable		 5mugA-1rk2A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 10 LEU A 212
ILE A 217
GLY A 216
LEU A 194
LEU A 173
 None
None
ALF  A 315 (-3.7A)
None
None
 1.11A 5twjB-1rk2A:
undetectable		 5twjB-1rk2A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1rk2 RIBOKINASE
(Escherichia
coli) 		5 / 12 LEU A 212
ILE A 217
GLY A 216
LEU A 194
LEU A 173
 None
None
ALF  A 315 (-3.7A)
None
None
 1.07A 5twjC-1rk2A:
undetectable		 5twjC-1rk2A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		4 / 5 ASN A 166
ASP A 255
ASN A  46
ASP A  16
 None
RIB  A 311 (-3.1A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.8A)
 1.15A 5vooA-1rk2A:
3.1		 5vooA-1rk2A:
26.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		4 / 5 ASP A 255
ASN A  46
ASP A  16
ASN A 108
 RIB  A 311 (-3.1A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.8A)
None
 1.23A 5vooA-1rk2A:
3.1		 5vooA-1rk2A:
26.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		4 / 5 ASP A 255
ASN A  46
ASP A  16
ASN A 108
 RIB  A 311 (-3.1A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.8A)
None
 1.23A 5vooB-1rk2A:
3.1		 5vooB-1rk2A:
26.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		4 / 5 ASN A 166
ASP A 255
ASN A  46
ASP A  16
 None
RIB  A 311 (-3.1A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.8A)
 1.16A 5vooC-1rk2A:
3.0		 5vooC-1rk2A:
26.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		4 / 5 ASP A 255
ASN A  46
ASP A  16
ASN A 108
 RIB  A 311 (-3.1A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.8A)
None
 1.25A 5vooC-1rk2A:
3.0		 5vooC-1rk2A:
26.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		4 / 5 ASP A 255
ASN A  46
ASP A  16
ASN A 108
 RIB  A 311 (-3.1A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.8A)
None
 1.25A 5vooD-1rk2A:
2.2		 5vooD-1rk2A:
26.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		4 / 5 ASP A 255
ASN A  46
ASP A  16
ASN A 108
 RIB  A 311 (-3.1A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.8A)
None
 1.24A 5vooE-1rk2A:
2.8		 5vooE-1rk2A:
26.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1rk2 RIBOKINASE
(Escherichia
coli) 		4 / 4 ASP A 255
ASN A  46
ASP A  16
ASN A 108
 RIB  A 311 (-3.1A)
RIB  A 311 (-3.3A)
RIB  A 311 (-2.8A)
None
 1.22A 5vooF-1rk2A:
2.6		 5vooF-1rk2A:
26.41