SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rki'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 1rki HYPOTHETICAL PROTEIN
(Pyrobaculum
aerophilum) 		5 / 10 ILE A  37
SER A  40
LYS A  41
GLY A  38
LYS A  35
 None
 1.29A 3ik6B-1rkiA:
undetectable
3ik6E-1rkiA:
undetectable		 3ik6B-1rkiA:
18.03
3ik6E-1rkiA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1rki HYPOTHETICAL PROTEIN
(Pyrobaculum
aerophilum) 		4 / 5 GLN A  56
TYR A  27
LEU A  63
LYS A  61
 None
 1.23A 3sugA-1rkiA:
undetectable		 3sugA-1rkiA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 1rki HYPOTHETICAL PROTEIN
(Pyrobaculum
aerophilum) 		3 / 3 LYS A   3
ILE A   5
ILE A  67
 None
 0.71A 4y0qA-1rkiA:
undetectable		 4y0qA-1rkiA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1rki HYPOTHETICAL PROTEIN
(Pyrobaculum
aerophilum) 		4 / 6 ILE A   7
PHE A  93
HIS A   4
PHE A  60
 None
 1.06A 5vkqA-1rkiA:
undetectable
5vkqB-1rkiA:
undetectable		 5vkqA-1rkiA:
4.41
5vkqB-1rkiA:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1rki HYPOTHETICAL PROTEIN
(Pyrobaculum
aerophilum) 		4 / 6 PHE A  60
ILE A   7
PHE A  93
HIS A   4
 None
 1.08A 5vkqA-1rkiA:
undetectable
5vkqD-1rkiA:
undetectable		 5vkqA-1rkiA:
4.41
5vkqD-1rkiA:
4.41