SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rkt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1rkt PROTEIN YFIR
(Bacillus
subtilis) 		4 / 8 ALA A 202
ILE A  88
GLY A 145
ILE A 146
 None
 0.76A 2o4nB-1rktA:
undetectable		 2o4nB-1rktA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 1rkt PROTEIN YFIR
(Bacillus
subtilis) 		5 / 11 LEU A  75
LEU A 141
ILE A  88
PHE A 134
LEU A 196
 None
 1.18A 2q6hA-1rktA:
0.5		 2q6hA-1rktA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 1rkt PROTEIN YFIR
(Bacillus
subtilis) 		5 / 11 LEU A  75
LEU A 141
ILE A  88
PHE A 134
LEU A 196
 None
 1.21A 2q72A-1rktA:
0.5		 2q72A-1rktA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 1rkt PROTEIN YFIR
(Bacillus
subtilis) 		5 / 11 LEU A  75
LEU A 141
ILE A  88
PHE A 134
LEU A 196
 None
 1.19A 2qeiA-1rktA:
0.6		 2qeiA-1rktA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 1rkt PROTEIN YFIR
(Bacillus
subtilis) 		5 / 11 LEU A  75
LEU A 141
ILE A  88
PHE A 134
LEU A 196
 None
 1.17A 2qjuA-1rktA:
0.0		 2qjuA-1rktA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 1rkt PROTEIN YFIR
(Bacillus
subtilis) 		6 / 12 LEU A 196
ALA A 202
ASP A 203
GLY A 149
ILE A 146
ILE A  88
 None
 1.35A 3s54B-1rktA:
undetectable		 3s54B-1rktA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 1rkt PROTEIN YFIR
(Bacillus
subtilis) 		5 / 11 LEU A  92
PHE A 151
LEU A 142
SER A  87
LEU A  75
 None
 1.33A 4zbqA-1rktA:
2.9		 4zbqA-1rktA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 1rkt PROTEIN YFIR
(Bacillus
subtilis) 		5 / 12 LEU A 114
SER A  55
PHE A  30
THR A 116
ARG A 124
 UNX  A 423 ( 4.8A)
None
None
None
None
 1.36A 5hnzB-1rktA:
undetectable		 5hnzB-1rktA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1rkt PROTEIN YFIR
(Bacillus
subtilis) 		3 / 3 GLU A 112
TYR A 113
ARG A 123
 None
 0.55A 5uunA-1rktA:
undetectable		 5uunA-1rktA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1rkt PROTEIN YFIR
(Bacillus
subtilis) 		3 / 3 GLU A 112
TYR A 113
ARG A 123
 None
 0.53A 5uunB-1rktA:
undetectable		 5uunB-1rktA:
22.92