SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rlk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 1rlk HYPOTHETICAL PROTEIN
TA0108
(Thermoplasma
acidophilum) 		4 / 6 PHE A  43
ILE A  38
ALA A  32
MET A   5
 None
 1.24A 1hk2A-1rlkA:
undetectable		 1hk2A-1rlkA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1rlk HYPOTHETICAL PROTEIN
TA0108
(Thermoplasma
acidophilum) 		4 / 7 MET A  36
PRO A 101
GLY A  50
TRP A  46
 None
 1.23A 2pnjB-1rlkA:
undetectable		 2pnjB-1rlkA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 1rlk HYPOTHETICAL PROTEIN
TA0108
(Thermoplasma
acidophilum) 		4 / 8 THR A 111
LEU A  99
GLY A  98
VAL A  58
 None
 0.87A 4c9nA-1rlkA:
undetectable		 4c9nA-1rlkA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 1rlk HYPOTHETICAL PROTEIN
TA0108
(Thermoplasma
acidophilum) 		3 / 3 ARG A  34
ILE A  38
SER A  35
 None
 0.81A 5zw2A-1rlkA:
undetectable		 5zw2A-1rlkA:
16.20