SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rms'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FO7_A_IMNA301_1 (PHOSPHOLIPASE A2 VRV-PL-VIIIA)	1rms	RIBONUCLEASE MS (Aspergillus phoenicis)	4 / 5	HIS A 39 ASP A 36 TYR A 37 PRO A 59	3GP A 106 (-4.0A) None 3GP A 106 (-4.3A) None	1.50A	3fo7A-1rmsA: undetectable	3fo7A-1rmsA: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H1X_A_IMNA301_1 (PHOSPHOLIPASE A2 VRV-PL-VIIIA)	1rms	RIBONUCLEASE MS (Aspergillus phoenicis)	4 / 5	HIS A 39 ASP A 36 TYR A 37 PRO A 59	3GP A 106 (-4.0A) None 3GP A 106 (-4.3A) None	1.49A	3h1xA-1rmsA: undetectable	3h1xA-1rmsA: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OLT_A_GCSA302_1 (CHITOSANASE)	1rms	RIBONUCLEASE MS (Aspergillus phoenicis)	4 / 5	THR A 92 THR A 90 ASP A 75 TYR A 12	None	1.37A	4oltA-1rmsA: 0.0	4oltA-1rmsA: 18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OLT_B_GCSB302_1 (CHITOSANASE)	1rms	RIBONUCLEASE MS (Aspergillus phoenicis)	4 / 5	THR A 92 THR A 90 ASP A 75 TYR A 12	None	1.37A	4oltB-1rmsA: undetectable	4oltB-1rmsA: 18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QB9_D_PARD500_1 (ENHANCED INTRACELLULAR SURVIVAL PROTEIN)	1rms	RIBONUCLEASE MS (Aspergillus phoenicis)	4 / 8	SER A 30 THR A 33 ASP A 35 ASP A 36	None	1.35A	4qb9D-1rmsA: undetectable	4qb9D-1rmsA: 13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_A_GCSA302_1 (CHITOSANASE)	1rms	RIBONUCLEASE MS (Aspergillus phoenicis)	4 / 5	THR A 92 THR A 90 ASP A 75 TYR A 12	None	1.38A	4qwpA-1rmsA: 0.0	4qwpA-1rmsA: 18.40

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3FO7_A_IMNA301_1","PHOSPHOLIPASE A2 VRV-PL-VIIIA","1rms","RIBONUCLEASE MS","Aspergillus phoenicis",4,"HIS A  39;ASP A  36;TYR A  37;PRO A  59","3GP A 106 (-4.0A);None;3GP A 106 (-4.3A);None","1.50A","3fo7A-1rmsA:undetectable","3fo7A-1rmsA:19.35"],["3H1X_A_IMNA301_1","PHOSPHOLIPASE A2 VRV-PL-VIIIA","1rms","RIBONUCLEASE MS","Aspergillus phoenicis",4,"HIS A  39;ASP A  36;TYR A  37;PRO A  59","3GP A 106 (-4.0A);None;3GP A 106 (-4.3A);None","1.49A","3h1xA-1rmsA:undetectable","3h1xA-1rmsA:19.35"],["4OLT_A_GCSA302_1","CHITOSANASE","1rms","RIBONUCLEASE MS","Aspergillus phoenicis",4,"THR A  92;THR A  90;ASP A  75;TYR A  12","None","1.37A","4oltA-1rmsA:0.0","4oltA-1rmsA:18.40"],["4OLT_B_GCSB302_1","CHITOSANASE","1rms","RIBONUCLEASE MS","Aspergillus phoenicis",4,"THR A  92;THR A  90;ASP A  75;TYR A  12","None","1.37A","4oltB-1rmsA:undetectable","4oltB-1rmsA:18.40"],["4QB9_D_PARD500_1","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","1rms","RIBONUCLEASE MS","Aspergillus phoenicis",4,"SER A  30;THR A  33;ASP A  35;ASP A  36","None","1.35A","4qb9D-1rmsA:undetectable","4qb9D-1rmsA:13.60"],["4QWP_A_GCSA302_1","CHITOSANASE","1rms","RIBONUCLEASE MS","Aspergillus phoenicis",4,"THR A  92;THR A  90;ASP A  75;TYR A  12","None","1.38A","4qwpA-1rmsA:0.0","4qwpA-1rmsA:18.40"]]