SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rpu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICU_D_NIOD223_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1rpu	19 KDA PROTEIN (Carnation Italian ringspot virus)	4 / 5	PHE A 116 GLY A 58 SER A 82 THR A 79	None	1.25A	1icuC-1rpuA: 0.0 1icuD-1rpuA: 0.0	1icuC-1rpuA: 21.40 1icuD-1rpuA: 21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICV_B_NIOB702_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1rpu	19 KDA PROTEIN (Carnation Italian ringspot virus)	4 / 5	PHE A 116 GLY A 58 SER A 82 THR A 79	None	1.24A	1icvA-1rpuA: 0.0 1icvB-1rpuA: 0.0	1icvA-1rpuA: 21.40 1icvB-1rpuA: 21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_G_SVRG506_1 (PHOSPHOLIPASE A2)	1rpu	19 KDA PROTEIN (Carnation Italian ringspot virus)	5 / 8	VAL A 68 VAL A 69 LYS A 71 PRO A 29 ARG A 11	None C C 10 ( 4.8A) A C 11 ( 2.9A) None C C 10 ( 2.7A)	1.41A	3bjwA-1rpuA: undetectable	3bjwA-1rpuA: 16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_C_CVIC301_1 (REGULATORY PROTEIN TETR)	1rpu	19 KDA PROTEIN (Carnation Italian ringspot virus)	4 / 7	GLY A 88 ILE A 138 GLN A 131 TYR A 112	None	1.08A	5vlmC-1rpuA: undetectable	5vlmC-1rpuA: 23.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ICU_D_NIOD223_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1rpu","19 KDA PROTEIN","Carnation Italian ringspot virus",4,"PHE A 116;GLY A  58;SER A  82;THR A  79","None","1.25A","1icuC-1rpuA:0.0;1icuD-1rpuA:0.0","1icuC-1rpuA:21.40;1icuD-1rpuA:21.40"],["1ICV_B_NIOB702_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1rpu","19 KDA PROTEIN","Carnation Italian ringspot virus",4,"PHE A 116;GLY A  58;SER A  82;THR A  79","None","1.24A","1icvA-1rpuA:0.0;1icvB-1rpuA:0.0","1icvA-1rpuA:21.40;1icvB-1rpuA:21.40"],["3BJW_G_SVRG506_1","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","1rpu","19 KDA PROTEIN","Carnation Italian ringspot virus",5,"VAL A  68;VAL A  69;LYS A  71;PRO A  29;ARG A  11","None;  C C  10 ( 4.8A);  A C  11 ( 2.9A);None;  C C  10 ( 2.7A)","1.41A","3bjwA-1rpuA:undetectable","3bjwA-1rpuA:16.95"],["5VLM_C_CVIC301_1","REGULATORY PROTEIN TETR","1rpu","19 KDA PROTEIN","Carnation Italian ringspot virus",4,"GLY A  88;ILE A 138;GLN A 131;TYR A 112","None","1.08A","5vlmC-1rpuA:undetectable","5vlmC-1rpuA:23.67"]]