SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		4 / 7 MET A 110
ASP A 111
ASP A 106
LYS A 258
 None
MG  A 909 (-2.4A)
None
RIS  A 901 (-2.7A)
 1.27A 1t03A-1rqjA:
undetectable		 1t03A-1rqjA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 11 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.31A 1yhlA-1rqjA:
31.1		 1yhlA-1rqjA:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 11 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.34A 1yq7A-1rqjA:
29.4		 1yq7A-1rqjA:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 10 ASP A 111
ARG A 116
GLN A 241
ASP A 244
LYS A 258
 MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 1.15A 1yv5A-1rqjA:
29.6		 1yv5A-1rqjA:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.30A 1yv5A-1rqjA:
29.6		 1yv5A-1rqjA:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 9 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.36A 1zw5A-1rqjA:
30.4		 1zw5A-1rqjA:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 12 LEU A 308
LEU A  72
TYR A 232
ALA A 215
ALA A 218
 None
 1.18A 2br4D-1rqjA:
undetectable		 2br4D-1rqjA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		8 / 9 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
 0.45A 2e91A-1rqjA:
21.5		 2e91A-1rqjA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		6 / 9 ASP A 105
ASP A 111
GLN A 179
LYS A 202
THR A 203
LYS A 268
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
MG  A 909 ( 4.2A)
 1.35A 2e91A-1rqjA:
21.5		 2e91A-1rqjA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		6 / 9 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
LYS A 268
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
MG  A 909 ( 4.2A)
 1.48A 2e91B-1rqjA:
20.5		 2e91B-1rqjA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		8 / 9 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
 0.62A 2e91B-1rqjA:
20.5		 2e91B-1rqjA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F89_F_210F9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		8 / 9 ASP A 105
ASP A 111
ARG A 116
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.31A 2f89F-1rqjA:
31.4		 2f89F-1rqjA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 11 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.32A 2f8cF-1rqjA:
30.6		 2f8cF-1rqjA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 10 ASP A 111
ARG A 116
GLN A 241
ASP A 244
LYS A 258
 MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 1.10A 2f8zF-1rqjA:
31.6		 2f8zF-1rqjA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.38A 2f8zF-1rqjA:
31.6		 2f8zF-1rqjA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 12 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.68A 2f94F-1rqjA:
30.1		 2f94F-1rqjA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.30A 2f9kF-1rqjA:
30.2		 2f9kF-1rqjA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		8 / 9 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
 0.40A 2o1oA-1rqjA:
25.8		 2o1oA-1rqjA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		7 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
LYS A 268
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
MG  A 909 ( 4.2A)
 1.09A 2o1oB-1rqjA:
26.6		 2o1oB-1rqjA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		8 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
 0.42A 2o1oB-1rqjA:
26.6		 2o1oB-1rqjA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		6 / 10 LEU A 102
ASP A 105
ARG A 116
GLN A 179
LYS A 202
ASP A 263
 None
MG  A 907 (-2.5A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
MG  A 908 ( 3.9A)
 1.19A 2q58A-1rqjA:
11.1		 2q58A-1rqjA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 245
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
None
 0.56A 2q58A-1rqjA:
11.1		 2q58A-1rqjA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		7 / 9 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
 0.42A 2q58B-1rqjA:
26.5		 2q58B-1rqjA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		6 / 9 ASP A 105
ASP A 111
GLN A 179
LYS A 202
THR A 203
LYS A 268
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
MG  A 909 ( 4.2A)
 1.23A 2q58B-1rqjA:
26.5		 2q58B-1rqjA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.28A 2qisA-1rqjA:
30.0		 2qisA-1rqjA:
26.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAT_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 12 ALA A  89
LEU A 146
LEU A 213
VAL A  73
LEU A 206
 None
 1.07A 3datA-1rqjA:
undetectable		 3datA-1rqjA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 9 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.39A 3ez3A-1rqjA:
29.3		 3ez3A-1rqjA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 9 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.32A 3ez3B-1rqjA:
29.1		 3ez3B-1rqjA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 9 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.37A 3ez3C-1rqjA:
29.3		 3ez3C-1rqjA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.33A 3ez3D-1rqjA:
28.8		 3ez3D-1rqjA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 10 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.40A 3ibaA-1rqjA:
30.8		 3ibaA-1rqjA:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 10 ALA A  89
LEU A 146
LEU A 213
VAL A  73
LEU A 206
 None
 1.14A 3jw5B-1rqjA:
undetectable		 3jw5B-1rqjA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 9 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.37A 3ldwA-1rqjA:
29.1		 3ldwA-1rqjA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 9 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.32A 3ldwB-1rqjA:
29.1		 3ldwB-1rqjA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 9 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.36A 3ldwC-1rqjA:
29.1		 3ldwC-1rqjA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 9 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.30A 3ldwD-1rqjA:
28.8		 3ldwD-1rqjA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 11 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.28A 3n45F-1rqjA:
30.3		 3n45F-1rqjA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.32A 3n46F-1rqjA:
30.0		 3n46F-1rqjA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		3 / 3 ARG A  41
PRO A  90
PHE A  42
 None
 0.74A 3thrC-1rqjA:
undetectable		 3thrC-1rqjA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		3 / 3 LYS A 258
ARG A  69
LEU A 102
 RIS  A 901 (-2.7A)
IPE  A 900 (-3.2A)
None
 1.41A 3v4tE-1rqjA:
undetectable		 3v4tE-1rqjA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		4 / 7 ALA A 137
ALA A  61
GLY A  60
ILE A  43
 None
 0.67A 4eatA-1rqjA:
undetectable		 4eatA-1rqjA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		4 / 7 ASP A 245
THR A 203
GLN A 265
LEU A 266
 None
IPE  A 900 ( 3.3A)
None
None
 1.10A 4ib4A-1rqjA:
2.9		 4ib4A-1rqjA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 9 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.31A 4kfaA-1rqjA:
30.0		 4kfaA-1rqjA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.32A 4kpdA-1rqjA:
31.2		 4kpdA-1rqjA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 9 LEU A 102
ASP A 105
ASP A 111
ARG A 116
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.31A 4kpjA-1rqjA:
29.9		 4kpjA-1rqjA:
26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.32A 4kq5A-1rqjA:
29.9		 4kq5A-1rqjA:
26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.31A 4kqsA-1rqjA:
31.2		 4kqsA-1rqjA:
26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.31A 4n9uA-1rqjA:
30.0		 4n9uA-1rqjA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 12 ASP A 105
ASP A 111
THR A 203
GLN A 179
ASP A 248
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
IPE  A 900 ( 3.3A)
RIS  A 901 (-3.2A)
MG  A 908 ( 4.7A)
 1.22A 4ng6A-1rqjA:
30.6		 4ng6A-1rqjA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 12 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.60A 4ng6A-1rqjA:
30.6		 4ng6A-1rqjA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.52A 4nkeA-1rqjA:
30.1		 4nkeA-1rqjA:
25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 9 LEU A 102
ASP A 105
ASP A 111
ARG A 116
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.38A 4nkfA-1rqjA:
30.0		 4nkfA-1rqjA:
25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.56A 4nuaA-1rqjA:
30.3		 4nuaA-1rqjA:
25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 9 LEU A 102
ASP A 105
ASP A 111
ARG A 116
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.35A 4oguA-1rqjA:
29.7		 4oguA-1rqjA:
25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0V_A_ZOLA401_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 9 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.31A 4p0vA-1rqjA:
31.2		 4p0vA-1rqjA:
27.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 11 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.37A 4p0wA-1rqjA:
31.0		 4p0wA-1rqjA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		9 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.29A 4q23A-1rqjA:
29.7		 4q23A-1rqjA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.29A 4rxdA-1rqjA:
30.1		 4rxdA-1rqjA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.28A 4rxdB-1rqjA:
30.3		 4rxdB-1rqjA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 10 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.28A 4rxdC-1rqjA:
30.4		 4rxdC-1rqjA:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		7 / 8 SER A 101
LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
 RIS  A 901 ( 3.8A)
None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
 0.66A 4umjA-1rqjA:
35.7		 4umjA-1rqjA:
52.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		7 / 8 SER A 101
LEU A 102
ASP A 105
ASP A 111
ARG A 116
MET A 175
LYS A 202
 RIS  A 901 ( 3.8A)
None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 ( 4.5A)
RIS  A 901 (-2.5A)
 0.73A 4umjA-1rqjA:
35.7		 4umjA-1rqjA:
52.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		7 / 9 SER A 101
LEU A 102
ASP A 105
ARG A 116
MET A 175
LYS A 202
THR A 203
 RIS  A 901 ( 3.8A)
None
MG  A 907 (-2.5A)
RIS  A 901 (-2.7A)
RIS  A 901 ( 4.5A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
 0.68A 4umjB-1rqjA:
35.8		 4umjB-1rqjA:
52.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		8 / 9 SER A 101
LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
 RIS  A 901 ( 3.8A)
None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
 0.53A 4umjB-1rqjA:
35.8		 4umjB-1rqjA:
52.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 12 ILE A 288
ALA A 284
ILE A 207
ARG A  69
ILE A 236
 None
None
None
IPE  A 900 (-3.2A)
None
 1.09A 4x5jA-1rqjA:
undetectable		 4x5jA-1rqjA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		4 / 6 GLU A  55
ILE A 132
HIS A 104
PRO A 120
 None
 1.06A 4xi3C-1rqjA:
0.3		 4xi3C-1rqjA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		4 / 6 HIS A  98
GLY A  65
GLU A  95
ARG A  67
 IPE  A 900 (-4.0A)
IPE  A 900 (-3.4A)
IPE  A 900 ( 4.8A)
None
 1.13A 4zbqA-1rqjA:
3.2		 4zbqA-1rqjA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 12 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.35A 5cg5A-1rqjA:
29.2		 5cg5A-1rqjA:
28.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		10 / 12 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
THR A 203
GLN A 241
ASP A 244
LYS A 258
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
IPE  A 900 ( 3.3A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
RIS  A 901 (-2.7A)
 0.29A 5cg6A-1rqjA:
30.1		 5cg6A-1rqjA:
28.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_A_210A804_1
(FUSICOCCADIENE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		7 / 9 LEU A 102
ASP A 105
ASP A 111
ARG A 116
LYS A 202
GLN A 241
ASP A 244
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-2.5A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
 0.62A 5eroA-1rqjA:
26.2		 5eroA-1rqjA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 9 ASP A 105
ARG A 116
LYS A 202
ASP A 245
LYS A 258
 MG  A 907 (-2.5A)
RIS  A 901 (-2.7A)
RIS  A 901 (-2.5A)
None
RIS  A 901 (-2.7A)
 1.43A 5eroB-1rqjA:
26.3		 5eroB-1rqjA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		7 / 9 ASP A 105
ASP A 111
ARG A 116
LYS A 202
GLN A 241
ASP A 244
ASP A 245
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-2.5A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
None
 0.64A 5eroB-1rqjA:
26.3		 5eroB-1rqjA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 9 ASP A 111
ARG A 116
GLN A 241
ASP A 244
ASP A 245
 MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
None
 1.26A 5eroB-1rqjA:
26.3		 5eroB-1rqjA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		8 / 10 ASP A 105
ASP A 106
ASP A 111
ARG A 116
LYS A 202
GLN A 241
ASP A 244
ASP A 245
 MG  A 907 (-2.5A)
None
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-2.5A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
None
 0.69A 5eroC-1rqjA:
26.3		 5eroC-1rqjA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		7 / 10 ASP A 105
ASP A 111
ARG A 116
LYS A 202
GLN A 241
ASP A 245
LYS A 258
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-2.5A)
RIS  A 901 ( 3.6A)
None
RIS  A 901 (-2.7A)
 1.09A 5eroC-1rqjA:
26.3		 5eroC-1rqjA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		6 / 10 ASP A 111
ASP A 106
ARG A 116
GLN A 241
ASP A 244
ASP A 245
 MG  A 909 (-2.4A)
None
RIS  A 901 (-2.7A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
None
 1.30A 5eroC-1rqjA:
26.3		 5eroC-1rqjA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 10 ASP A 111
ASP A 113
GLN A 241
ASP A 244
ASP A 245
 MG  A 909 (-2.4A)
MG  A 907 ( 4.9A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
None
 1.08A 5eroC-1rqjA:
26.3		 5eroC-1rqjA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		6 / 10 ASP A 113
ASP A 111
LYS A 202
GLN A 241
ASP A 244
ASP A 245
 MG  A 907 ( 4.9A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.5A)
RIS  A 901 ( 3.6A)
MG  A 908 ( 2.7A)
None
 1.46A 5eroC-1rqjA:
26.3		 5eroC-1rqjA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		3 / 3 VAL A 154
LEU A 303
MET A  79
 None
 0.61A 5ikrA-1rqjA:
undetectable		 5ikrA-1rqjA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 9 LEU A 213
VAL A  73
VAL A  94
ILE A 145
ASP A  88
 None
 1.24A 5yf9X-1rqjA:
undetectable		 5yf9X-1rqjA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		4 / 5 ARG A 292
ALA A 291
TYR A 232
ILE A 315
 None
 1.26A 6f6sA-1rqjA:
undetectable
6f6sB-1rqjA:
undetectable		 6f6sA-1rqjA:
17.36
6f6sB-1rqjA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		6 / 7 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
GLN A 241
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
RIS  A 901 ( 3.6A)
 1.06A 6g31A-1rqjA:
24.3		 6g31A-1rqjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_B_ZOLB401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 6 ASP A 105
ASP A 111
ARG A 116
GLN A 179
GLN A 241
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 ( 3.6A)
 0.71A 6g31B-1rqjA:
24.5		 6g31B-1rqjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_C_ZOLC401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 5 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
 1.20A 6g31C-1rqjA:
24.7		 6g31C-1rqjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		6 / 7 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
GLN A 241
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 ( 3.6A)
 0.58A 6g31D-1rqjA:
23.8		 6g31D-1rqjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_E_ZOLE401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		4 / 4 LEU A 102
ASP A 105
ASP A 111
ARG A 116
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
 0.37A 6g31E-1rqjA:
18.7		 6g31E-1rqjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_F_ZOLF401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 5 ASP A 105
ASP A 111
ARG A 116
GLN A 179
GLN A 241
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 ( 3.6A)
 0.63A 6g31F-1rqjA:
24.6		 6g31F-1rqjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		6 / 7 ASP A 105
ASP A 111
ARG A 116
GLN A 179
LYS A 202
GLN A 241
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 (-2.5A)
RIS  A 901 ( 3.6A)
 0.64A 6g31G-1rqjA:
23.2		 6g31G-1rqjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_H_ZOLH401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		4 / 5 ASP A 105
ASP A 111
GLN A 179
GLN A 241
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-3.2A)
RIS  A 901 ( 3.6A)
 0.51A 6g31H-1rqjA:
23.3		 6g31H-1rqjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_H_ZOLH401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		4 / 5 ASP A 105
ASP A 111
GLN A 179
LYS A 268
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-3.2A)
MG  A 909 ( 4.2A)
 1.42A 6g31H-1rqjA:
23.3		 6g31H-1rqjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_I_ZOLI401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		4 / 4 ASP A 105
ASP A 111
LYS A 202
GLN A 241
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.5A)
RIS  A 901 ( 3.6A)
 0.95A 6g31I-1rqjA:
23.8		 6g31I-1rqjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 6 LEU A 102
ASP A 105
ASP A 111
ARG A 116
GLN A 179
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
 0.86A 6g31J-1rqjA:
24.7		 6g31J-1rqjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		5 / 6 LEU A 102
ASP A 105
ASP A 111
GLN A 179
GLN A 241
 None
MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-3.2A)
RIS  A 901 ( 3.6A)
 0.60A 6g31J-1rqjA:
24.7		 6g31J-1rqjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_K_ZOLK401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		4 / 4 ASP A 105
ASP A 111
ARG A 116
GLN A 179
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
 0.51A 6g31K-1rqjA:
22.5		 6g31K-1rqjA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rqj GERANYLTRANSTRANSFER
ASE
(Escherichia
coli) 		6 / 6 ASP A 105
ASP A 111
ARG A 116
GLN A 179
GLN A 241
LYS A 268
 MG  A 907 (-2.5A)
MG  A 909 (-2.4A)
RIS  A 901 (-2.7A)
RIS  A 901 (-3.2A)
RIS  A 901 ( 3.6A)
MG  A 909 ( 4.2A)
 1.15A 6g31L-1rqjA:
24.2		 6g31L-1rqjA:
13.47