SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rra'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DY5_A_ACTA600_0 (RIBONUCLEASE A)	1rra	PROTEIN (RIBONUCLEASE) (Rattus norvegicus)	4 / 4	HIS A 12 VAL A 43 ASN A 44 THR A 45	PO4 A 125 (-3.6A) None None None	0.35A	1dy5A-1rraA: 21.6	1dy5A-1rraA: 66.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1N3Z_A_ADNA126_1 (RIBONUCLEASE, SEMINAL)	1rra	PROTEIN (RIBONUCLEASE) (Rattus norvegicus)	5 / 9	LYS A 7 ASN A 67 ASN A 71 ALA A 109 VAL A 118	None	0.62A	1n3zA-1rraA: 21.6	1n3zA-1rraA: 66.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DNU_A_BEZA319_0 (SHKAI2IB)	1rra	PROTEIN (RIBONUCLEASE) (Rattus norvegicus)	4 / 5	GLN A 60 HIS A 105 ILE A 57 ILE A 107	None	1.18A	5dnuA-1rraA: undetectable	5dnuA-1rraA: 17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DNV_A_BEZA304_0 (SHKAI2IB)	1rra	PROTEIN (RIBONUCLEASE) (Rattus norvegicus)	4 / 5	GLN A 60 HIS A 105 ILE A 57 ILE A 107	None	1.18A	5dnvA-1rraA: undetectable	5dnvA-1rraA: 17.56