SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rtr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 8 LEU A 115
SER A  37
ASN A  99
GLN A  29
 None
 1.12A 1ig3A-1rtrA:
undetectable
1ig3B-1rtrA:
undetectable		 1ig3A-1rtrA:
22.12
1ig3B-1rtrA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		3 / 3 THR A 199
LEU A 203
LEU A 210
 None
 0.41A 1mz9C-1rtrA:
undetectable		 1mz9C-1rtrA:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		3 / 3 THR A 278
LEU A 282
VAL A 285
 None
 0.35A 1mz9E-1rtrA:
undetectable		 1mz9E-1rtrA:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 12 ALA A 119
PHE A 120
ALA A  70
VAL A  13
LEU A  51
 None
 1.27A 1rbpA-1rtrA:
undetectable		 1rbpA-1rtrA:
19.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 11 SER A  78
LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.69A 1rqjA-1rtrA:
34.5		 1rqjA-1rtrA:
41.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 11 SER A  78
LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.91A 1rqjA-1rtrA:
34.5		 1rqjA-1rtrA:
41.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 11 SER A  78
LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.70A 1rqjB-1rtrA:
34.7		 1rqjB-1rtrA:
41.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 11 SER A  78
LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.88A 1rqjB-1rtrA:
34.7		 1rqjB-1rtrA:
41.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 8 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.55A 1rtsA-1rtrA:
undetectable		 1rtsA-1rtrA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.53A 1rtsB-1rtrA:
undetectable		 1rtsB-1rtrA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 4 LEU A 181
SER A  78
LEU A 141
LEU A  71
 None
 1.18A 1yajA-1rtrA:
undetectable		 1yajA-1rtrA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 11 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.81A 1yhlA-1rtrA:
25.0		 1yhlA-1rtrA:
27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 11 LEU A  79
ASP A  82
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 1.16A 1yq7A-1rtrA:
25.0		 1yq7A-1rtrA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 ASP A  82
ASP A  88
ARG A  93
LYS A 177
THR A 178
 None
 1.22A 1yv5A-1rtrA:
25.2		 1yv5A-1rtrA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 10 LEU A  79
ASP A  82
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 1.03A 1yv5A-1rtrA:
25.2		 1yv5A-1rtrA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.85A 1yv5A-1rtrA:
25.2		 1yv5A-1rtrA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 9 ASP A  82
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 1.21A 1zw5A-1rtrA:
25.1		 1zw5A-1rtrA:
26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 11 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.13A 2f8cF-1rtrA:
25.7		 2f8cF-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 11 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.75A 2f8cF-1rtrA:
25.7		 2f8cF-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 11 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.84A 2f8cF-1rtrA:
25.7		 2f8cF-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.13A 2f8zF-1rtrA:
25.8		 2f8zF-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.72A 2f8zF-1rtrA:
25.8		 2f8zF-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.85A 2f8zF-1rtrA:
25.8		 2f8zF-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 12 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
GLN A 215
 None
 0.84A 2f94F-1rtrA:
25.6		 2f94F-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.15A 2f9kF-1rtrA:
25.7		 2f9kF-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.72A 2f9kF-1rtrA:
25.7		 2f9kF-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.84A 2f9kF-1rtrA:
25.7		 2f9kF-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 8 MET A 150
SER A 145
ALA A  70
LEU A  71
 None
 1.07A 2o01A-1rtrA:
1.4		 2o01A-1rtrA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 9 LEU A  79
ASP A  82
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 1.06A 2o1oA-1rtrA:
23.9		 2o1oA-1rtrA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 9 LEU A  79
ASP A  88
ARG A  93
GLN A 154
LYS A 177
THR A 178
 None
 1.00A 2o1oA-1rtrA:
23.9		 2o1oA-1rtrA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 10 LEU A  79
ASP A  82
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 1.17A 2o1oB-1rtrA:
24.6		 2o1oB-1rtrA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 1.00A 2o1oB-1rtrA:
24.6		 2o1oB-1rtrA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 10 LEU A  79
ASP A  82
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 1.28A 2q58A-1rtrA:
24.0		 2q58A-1rtrA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 9 ASP A  82
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 1.28A 2q58B-1rtrA:
24.3		 2q58B-1rtrA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.52A 2tsrA-1rtrA:
undetectable		 2tsrA-1rtrA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 8 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.68A 2tsrB-1rtrA:
undetectable		 2tsrB-1rtrA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 6 ALA A 119
LEU A 122
ALA A  20
ASN A  22
 None
 0.85A 3b6hA-1rtrA:
1.5		 3b6hA-1rtrA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 6 ALA A 119
LEU A 122
ALA A  20
ASN A  22
 None
 0.86A 3b6hB-1rtrA:
2.0		 3b6hB-1rtrA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 12 LEU A  71
GLY A 179
LEU A 182
LEU A 141
HIS A  75
 None
 1.19A 3e23A-1rtrA:
undetectable		 3e23A-1rtrA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.15A 3ez3D-1rtrA:
23.8		 3ez3D-1rtrA:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.73A 3ez3D-1rtrA:
23.8		 3ez3D-1rtrA:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.87A 3ez3D-1rtrA:
23.8		 3ez3D-1rtrA:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 ASP A  82
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 1.28A 3ibaA-1rtrA:
25.0		 3ibaA-1rtrA:
27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 9 LEU A  17
ILE A  69
ALA A  70
GLU A  72
THR A  76
 None
 1.14A 3mdvA-1rtrA:
undetectable		 3mdvA-1rtrA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 11 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.14A 3n45F-1rtrA:
25.5		 3n45F-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 11 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.74A 3n45F-1rtrA:
25.5		 3n45F-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 11 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.86A 3n45F-1rtrA:
25.5		 3n45F-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.11A 3n46F-1rtrA:
25.7		 3n46F-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.73A 3n46F-1rtrA:
25.7		 3n46F-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.84A 3n46F-1rtrA:
25.7		 3n46F-1rtrA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 5 ASN A  99
ASP A  90
GLU A 161
SER A  37
 None
 1.13A 3p2kC-1rtrA:
undetectable		 3p2kC-1rtrA:
25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 12 TYR A 208
GLY A 179
LEU A 210
SER A 207
HIS A 261
 None
 0.92A 3pfgA-1rtrA:
undetectable		 3pfgA-1rtrA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 9 LEU A 129
THR A 130
VAL A 133
LEU A  54
ILE A 192
 None
 1.16A 3tbgD-1rtrA:
undetectable		 3tbgD-1rtrA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 LEU A  52
GLY A  64
GLU A  62
ALA A  68
 None
 1.00A 3tehB-1rtrA:
undetectable		 3tehB-1rtrA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 11 GLY A 179
ALA A 180
VAL A 151
GLY A 152
GLY A 153
ILE A 173
 None
 1.45A 3ufnA-1rtrA:
undetectable		 3ufnA-1rtrA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 GLU A 201
GLU A 204
HIS A 261
VAL A 285
 None
 1.06A 4a97H-1rtrA:
undetectable		 4a97H-1rtrA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.55A 4iqqA-1rtrA:
undetectable		 4iqqA-1rtrA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.57A 4iqqB-1rtrA:
undetectable		 4iqqB-1rtrA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.69A 4iqqC-1rtrA:
undetectable		 4iqqC-1rtrA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 8 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.45A 4iqqD-1rtrA:
undetectable		 4iqqD-1rtrA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.13A 4kpdA-1rtrA:
25.8		 4kpdA-1rtrA:
25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.70A 4kpdA-1rtrA:
25.8		 4kpdA-1rtrA:
25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.82A 4kpdA-1rtrA:
25.8		 4kpdA-1rtrA:
25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 9 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.84A 4kpjA-1rtrA:
25.5		 4kpjA-1rtrA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.15A 4kq5A-1rtrA:
25.5		 4kq5A-1rtrA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.71A 4kq5A-1rtrA:
25.5		 4kq5A-1rtrA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.15A 4kqsA-1rtrA:
25.8		 4kqsA-1rtrA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.73A 4kqsA-1rtrA:
25.8		 4kqsA-1rtrA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.84A 4kqsA-1rtrA:
25.8		 4kqsA-1rtrA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 8 PHE A 288
TYR A 206
GLY A 211
ALA A 185
 None
 0.92A 4m48A-1rtrA:
1.9		 4m48A-1rtrA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.85A 4n9uA-1rtrA:
25.5		 4n9uA-1rtrA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 12 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.07A 4ng6A-1rtrA:
25.5		 4ng6A-1rtrA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 12 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
GLN A 215
 None
 0.89A 4ng6A-1rtrA:
25.5		 4ng6A-1rtrA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.13A 4nkeA-1rtrA:
25.7		 4nkeA-1rtrA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.73A 4nkeA-1rtrA:
25.7		 4nkeA-1rtrA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.85A 4nkeA-1rtrA:
25.7		 4nkeA-1rtrA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 9 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.81A 4nkfA-1rtrA:
25.7		 4nkfA-1rtrA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.14A 4nuaA-1rtrA:
25.7		 4nuaA-1rtrA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.72A 4nuaA-1rtrA:
25.7		 4nuaA-1rtrA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.82A 4nuaA-1rtrA:
25.7		 4nuaA-1rtrA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 9 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.82A 4oguA-1rtrA:
25.6		 4oguA-1rtrA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 11 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.14A 4p0wA-1rtrA:
25.6		 4p0wA-1rtrA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 11 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.70A 4p0wA-1rtrA:
25.6		 4p0wA-1rtrA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 11 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.81A 4p0wA-1rtrA:
25.6		 4p0wA-1rtrA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.20A 4rxdA-1rtrA:
24.2		 4rxdA-1rtrA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.79A 4rxdA-1rtrA:
24.2		 4rxdA-1rtrA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.88A 4rxdA-1rtrA:
24.2		 4rxdA-1rtrA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.18A 4rxdB-1rtrA:
24.5		 4rxdB-1rtrA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.78A 4rxdB-1rtrA:
24.5		 4rxdB-1rtrA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.87A 4rxdB-1rtrA:
24.5		 4rxdB-1rtrA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.18A 4rxdC-1rtrA:
24.5		 4rxdC-1rtrA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.77A 4rxdC-1rtrA:
24.5		 4rxdC-1rtrA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.88A 4rxdC-1rtrA:
24.5		 4rxdC-1rtrA:
26.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		6 / 8 SER A  78
LEU A  79
ASP A  88
ARG A  93
MET A 150
GLN A 154
 None
 0.59A 4umjA-1rtrA:
36.7		 4umjA-1rtrA:
37.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 9 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 0.98A 4umjB-1rtrA:
36.9		 4umjB-1rtrA:
37.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		7 / 9 SER A  78
LEU A  79
ASP A  88
ARG A  93
MET A 150
GLN A 154
THR A 178
 None
 0.42A 4umjB-1rtrA:
36.9		 4umjB-1rtrA:
37.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 12 THR A 117
LEU A 115
ALA A 114
LEU A 110
LEU A  30
 None
 0.98A 4xi3C-1rtrA:
undetectable		 4xi3C-1rtrA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 6 HIS A  75
GLY A  42
GLU A  72
ARG A  44
 None
 1.22A 4zbqA-1rtrA:
2.1		 4zbqA-1rtrA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 12 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.14A 5cg5A-1rtrA:
25.0		 5cg5A-1rtrA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 12 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.71A 5cg5A-1rtrA:
25.0		 5cg5A-1rtrA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 12 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.82A 5cg5A-1rtrA:
25.0		 5cg5A-1rtrA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 12 LEU A  79
ASP A  82
ARG A  93
GLN A 154
THR A 178
 None
 1.13A 5cg6A-1rtrA:
25.6		 5cg6A-1rtrA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 12 LEU A  79
ASP A  88
ARG A  93
GLN A 154
THR A 178
 None
 0.70A 5cg6A-1rtrA:
25.6		 5cg6A-1rtrA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 12 LEU A  79
ASP A  88
ARG A  93
THR A 178
GLN A 215
 None
 0.84A 5cg6A-1rtrA:
25.6		 5cg6A-1rtrA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		3 / 3 ASP A 218
LEU A  79
ARG A  93
 None
 0.63A 5e8qA-1rtrA:
undetectable		 5e8qA-1rtrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.46A 5h3aB-1rtrA:
undetectable		 5h3aB-1rtrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		3 / 3 LYS A 175
LEU A 167
ILE A 216
 None
 0.80A 5kc4A-1rtrA:
1.7		 5kc4A-1rtrA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 LEU A  63
SER A  67
ILE A 135
ASP A 126
 None
 0.89A 5n5dA-1rtrA:
undetectable		 5n5dA-1rtrA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.57A 5nooA-1rtrA:
undetectable		 5nooA-1rtrA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.57A 5nooB-1rtrA:
undetectable		 5nooB-1rtrA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 8 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.50A 5nooD-1rtrA:
undetectable		 5nooD-1rtrA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 6 LEU A  50
LEU A  71
LEU A  38
GLU A  16
 None
 0.93A 5tudD-1rtrA:
2.2		 5tudD-1rtrA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.54A 5x5qC-1rtrA:
undetectable		 5x5qC-1rtrA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 8 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.54A 5x5qD-1rtrA:
undetectable		 5x5qD-1rtrA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 8 ILE A  45
LEU A 210
GLY A 211
PHE A 214
 None
 0.57A 5x5qF-1rtrA:
undetectable		 5x5qF-1rtrA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 LEU A  79
ASP A  82
ARG A  93
GLN A 154
 None
 1.26A 6g31D-1rtrA:
22.0		 6g31D-1rtrA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 LEU A  79
ASP A  88
ARG A  93
GLN A 154
 None
 0.73A 6g31D-1rtrA:
22.0		 6g31D-1rtrA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 7 LEU A  79
ASP A  88
ARG A  93
GLN A 215
 None
 0.92A 6g31D-1rtrA:
22.0		 6g31D-1rtrA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 6 LEU A  79
ASP A  82
ARG A  93
GLN A 154
 None
 1.33A 6g31J-1rtrA:
22.8		 6g31J-1rtrA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		4 / 6 LEU A  79
ASP A  88
ARG A  93
GLN A 154
 None
 0.91A 6g31J-1rtrA:
22.8		 6g31J-1rtrA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 1rtr GERANYLTRANSTRANSFER
ASE
(Staphylococcus
aureus) 		5 / 12 THR A 199
ILE A 272
TYR A 206
LEU A  57
LEU A  49
 None
 1.32A 6ie8A-1rtrA:
2.5		 6ie8A-1rtrA:
22.94