SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rty'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 1rty YVQK PROTEIN
(Bacillus
subtilis) 		5 / 11 LEU A  67
VAL A  90
ILE A  33
LEU A  74
ASP A  73
 None
 0.99A 2q6hA-1rtyA:
undetectable		 2q6hA-1rtyA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 1rty YVQK PROTEIN
(Bacillus
subtilis) 		5 / 11 LEU A  67
VAL A  90
ILE A  33
LEU A  74
ASP A  73
 None
 0.99A 2q72A-1rtyA:
undetectable		 2q72A-1rtyA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 1rty YVQK PROTEIN
(Bacillus
subtilis) 		5 / 11 LEU A  67
VAL A  90
ILE A  33
LEU A  74
ASP A  73
 None
 1.01A 2qeiA-1rtyA:
undetectable		 2qeiA-1rtyA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_1
(DEOXYCYTIDINE KINASE)		 1rty YVQK PROTEIN
(Bacillus
subtilis) 		5 / 12 GLU A 103
TYR A 159
ARG A 170
ARG A  96
GLU A  59
 None
 1.10A 2zi9A-1rtyA:
1.4		 2zi9A-1rtyA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1rty YVQK PROTEIN
(Bacillus
subtilis) 		5 / 12 GLY A 163
ILE A  40
LEU A  44
LEU A 156
TYR A 152
 None
 1.30A 3cs8A-1rtyA:
undetectable		 3cs8A-1rtyA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1rty YVQK PROTEIN
(Bacillus
subtilis) 		4 / 6 LEU A  93
TYR A 152
ILE A  40
THR A 129
 None
 0.95A 4l39A-1rtyA:
undetectable		 4l39A-1rtyA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1rty YVQK PROTEIN
(Bacillus
subtilis) 		4 / 7 LEU A  93
TYR A 152
ILE A  40
THR A 129
 None
 0.93A 4l39B-1rtyA:
undetectable		 4l39B-1rtyA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1rty YVQK PROTEIN
(Bacillus
subtilis) 		4 / 6 TYR A 159
GLU A  66
TYR A 152
LEU A 153
 None
 1.28A 4twdD-1rtyA:
4.1
4twdE-1rtyA:
4.2		 4twdD-1rtyA:
22.79
4twdE-1rtyA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1rty YVQK PROTEIN
(Bacillus
subtilis) 		4 / 6 TYR A 159
GLU A  66
TYR A 152
LEU A 153
 None
 1.39A 4twdF-1rtyA:
undetectable
4twdG-1rtyA:
undetectable		 4twdF-1rtyA:
22.79
4twdG-1rtyA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 1rty YVQK PROTEIN
(Bacillus
subtilis) 		5 / 10 LEU A  93
ILE A  40
PHE A  68
LEU A  85
GLU A  94
 None
 1.09A 5y7pG-1rtyA:
undetectable		 5y7pG-1rtyA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 1rty YVQK PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A 115
GLY A 114
ILE A 173
ALA A 119
GLY A 174
 None
 1.11A 6e5zA-1rtyA:
undetectable		 6e5zA-1rtyA:
22.58