SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1rur IMMUNOGLOBULIN 13G5,
HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 117
PRO H 149
THR H 116
PRO H 118
 None
 1.35A 1dsdC-1rurH:
undetectable		 1dsdC-1rurH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1rur IMMUNOGLOBULIN 13G5,
HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 117
PRO H 149
THR H 116
PRO H 118
 None
 1.35A 1dsdC-1rurH:
undetectable		 1dsdC-1rurH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 1rur IMMUNOGLOBULIN 13G5,
HEAVY CHAIN
(Mus
musculus) 		4 / 8 SER H  74
PHE H  29
ALA H  24
LEU H  34
 None
 1.10A 2bxkA-1rurH:
undetectable		 2bxkA-1rurH:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 1rur IMMUNOGLOBULIN 13G5,
HEAVY CHAIN
(Mus
musculus) 		5 / 10 SER H  74
PHE H  29
ALA H  24
LEU H   4
LEU H  34
 None
 1.09A 2bxqA-1rurH:
undetectable		 2bxqA-1rurH:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1rur IMMUNOGLOBULIN 13G5,
HEAVY CHAIN
(Mus
musculus) 		5 / 12 VAL H 171
VAL H 191
SER H 189
ASN H 209
ASN H 162
 None
 1.43A 2y03A-1rurH:
undetectable		 2y03A-1rurH:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1rur IMMUNOGLOBULIN 13G5,
HEAVY CHAIN
(Mus
musculus) 		5 / 12 VAL H 171
VAL H 191
SER H 189
ASN H 209
ASN H 162
 None
 1.46A 2y03B-1rurH:
undetectable		 2y03B-1rurH:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 1rur IMMUNOGLOBULIN 13G5,
HEAVY CHAIN
(Mus
musculus) 		4 / 5 ILE H  51
PRO H  52
TYR H  52
TYR H  56
 None
 1.16A 3d9lA-1rurH:
undetectable
3d9lY-1rurH:
undetectable		 3d9lA-1rurH:
17.59
3d9lY-1rurH:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 1rur IMMUNOGLOBULIN 13G5,
HEAVY CHAIN
(Mus
musculus) 		5 / 12 VAL H 171
VAL H 191
SER H 189
ASN H 209
ASN H 162
 None
 1.41A 3nyaA-1rurH:
undetectable		 3nyaA-1rurH:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 1rur IMMUNOGLOBULIN 13G5,
HEAVY CHAIN
(Mus
musculus) 		5 / 10 VAL H 171
VAL H 191
SER H 189
ASN H 209
ASN H 162
 None
 1.49A 4ldoA-1rurH:
undetectable		 4ldoA-1rurH:
18.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 1rur IMMUNOGLOBULIN 13G5,
HEAVY CHAIN
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  94
TYR H 102
 None
 0.23A 4m7kH-1rurH:
28.2		 4m7kH-1rurH:
68.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 1rur IMMUNOGLOBULIN 13G5,
HEAVY CHAIN
(Mus
musculus) 		4 / 5 SER H 112
ALA H 114
PHE H 148
LEU H 178
 None
 0.36A 5mthA-1rurH:
19.4		 5mthA-1rurH:
84.47