SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1rv9 CONSERVED
HYPOTHETICAL PROTEIN
NMB0706
(Neisseria
meningitidis) 		5 / 10 ALA A 204
PHE A 173
ALA A 190
VAL A 145
ILE A 213
 None
 1.13A 1claA-1rv9A:
undetectable		 1claA-1rv9A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1rv9 CONSERVED
HYPOTHETICAL PROTEIN
NMB0706
(Neisseria
meningitidis) 		5 / 9 PHE A 123
LEU A 141
VAL A 145
GLY A 144
ILE A 150
 None
 1.30A 2a1oB-1rv9A:
undetectable		 2a1oB-1rv9A:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 1rv9 CONSERVED
HYPOTHETICAL PROTEIN
NMB0706
(Neisseria
meningitidis) 		4 / 5 ALA A 182
TRP A 138
LEU A 206
ALA A 142
 None
 1.19A 2jstA-1rv9A:
0.0
2jstB-1rv9A:
0.0		 2jstA-1rv9A:
13.78
2jstB-1rv9A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1rv9 CONSERVED
HYPOTHETICAL PROTEIN
NMB0706
(Neisseria
meningitidis) 		4 / 6 LEU A  78
ALA A 133
LEU A 251
ALA A 110
 None
 0.96A 2vcvB-1rv9A:
undetectable		 2vcvB-1rv9A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1rv9 CONSERVED
HYPOTHETICAL PROTEIN
NMB0706
(Neisseria
meningitidis) 		4 / 8 LEU A 146
ARG A 211
SER A 250
GLY A 224
 None
 1.13A 3hcrA-1rv9A:
undetectable		 3hcrA-1rv9A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 1rv9 CONSERVED
HYPOTHETICAL PROTEIN
NMB0706
(Neisseria
meningitidis) 		3 / 3 ASP A 117
ARG A 240
TYR A 239
 None
 0.93A 5a7mA-1rv9A:
2.3		 5a7mA-1rv9A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 1rv9 CONSERVED
HYPOTHETICAL PROTEIN
NMB0706
(Neisseria
meningitidis) 		3 / 3 ASP A 117
ARG A 240
TYR A 239
 None
 0.96A 5a7mB-1rv9A:
undetectable		 5a7mB-1rv9A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1rv9 CONSERVED
HYPOTHETICAL PROTEIN
NMB0706
(Neisseria
meningitidis) 		4 / 5 TYR A 163
TYR A 223
GLY A 224
GLY A 225
 None
 1.23A 5x7pA-1rv9A:
1.8		 5x7pA-1rv9A:
12.03