SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rvf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_A_SAMA500_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 1rvf FAB 17-IA
FAB 17-IA
(Mus
musculus;
Mus
musculus) 		5 / 12 ASN H  35
GLY L  99
SER L 100
THR L   5
TYR L  87
 None
 1.42A 1g60A-1rvfH:
undetectable		 1g60A-1rvfH:
16.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 1rvf FAB 17-IA
(Mus
musculus) 		8 / 12 GLN L  89
TYR L  94
PHE L  98
TRP H  33
ASN H  35
VAL H  37
ALA H  93
TRP H 103
 None
 0.88A 1h8sA-1rvfL:
17.9		 1h8sA-1rvfL:
33.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 1rvf FAB 17-IA
FAB 17-IA
(Mus
musculus;
Mus
musculus) 		3 / 3 PHE H  91
TYR L  87
PRO L  44
 None
 1.18A 1mcnA-1rvfH:
14.3
1mcnB-1rvfH:
14.9
1mcnP-1rvfH:
undetectable		 1mcnA-1rvfH:
22.02
1mcnB-1rvfH:
22.02
1mcnP-1rvfH:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.69A 1usqA-1rvfH:
undetectable		 1usqA-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.69A 1usqB-1rvfH:
undetectable		 1usqB-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.69A 1usqC-1rvfH:
undetectable		 1usqC-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.70A 1usqD-1rvfH:
undetectable		 1usqD-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.71A 1usqE-1rvfH:
undetectable		 1usqE-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.68A 1usqF-1rvfH:
undetectable		 1usqF-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.76A 2jkjA-1rvfH:
undetectable		 2jkjA-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.76A 2jkjB-1rvfH:
undetectable		 2jkjB-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.76A 2jkjC-1rvfH:
undetectable		 2jkjC-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.76A 2jkjE-1rvfH:
undetectable		 2jkjE-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.74A 2jklA-1rvfH:
undetectable		 2jklA-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.75A 2jklB-1rvfH:
undetectable		 2jklB-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.74A 2jklC-1rvfH:
undetectable		 2jklC-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.75A 2jklD-1rvfH:
undetectable		 2jklD-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.75A 2jklE-1rvfH:
undetectable		 2jklE-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.75A 2jklF-1rvfH:
undetectable		 2jklF-1rvfH:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1rvf FAB 17-IA
FAB 17-IA
(Mus
musculus;
Mus
musculus) 		3 / 3 ASN H  35
MET L  33
PHE L  98
 None
 1.08A 3g4lD-1rvfH:
undetectable		 3g4lD-1rvfH:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 6 GLN L  89
PHE L  98
ILE L  96
PRO L  95
 None
 1.17A 4fgkA-1rvfL:
undetectable		 4fgkA-1rvfL:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1rvf FAB 17-IA
(Mus
musculus) 		3 / 4 ARG H  40
GLY H  44
GLU H  46
 None
 0.64A 4z2dB-1rvfH:
undetectable
4z2dC-1rvfH:
undetectable		 4z2dB-1rvfH:
11.52
4z2dC-1rvfH:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1rvf FAB 17-IA
(Mus
musculus) 		4 / 6 PHE L  14
PRO L  15
GLY L  16
LYS L  18
 None
 0.84A 5x24A-1rvfL:
undetectable		 5x24A-1rvfL:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 1rvf FAB 17-IA
FAB 17-IA
(Mus
musculus;
Mus
musculus) 		4 / 5 ASN H  97
VAL L  58
LEU L  54
SER L  50
 None
 1.14A 6a7pA-1rvfH:
undetectable		 6a7pA-1rvfH:
12.47