SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rvk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 ARG A 280
TYR A 243
SER A 136
TYR A 134
 MG  A 999 ( 4.9A)
None
None
None
 1.28A 1nx9A-1rvkA:
undetectable		 1nx9A-1rvkA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 ARG A 280
TYR A 243
SER A 136
TYR A 134
 MG  A 999 ( 4.9A)
None
None
None
 1.29A 1nx9B-1rvkA:
undetectable		 1nx9B-1rvkA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 9 GLY A 331
SER A 136
LEU A 333
TYR A 153
HIS A 171
 None
 1.34A 1y7iA-1rvkA:
undetectable		 1y7iA-1rvkA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 7 THR A 100
LEU A  70
VAL A  66
ASP A 105
 None
 0.87A 2cppA-1rvkA:
0.0		 2cppA-1rvkA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_E_H4BE1004_1
(HYPOTHETICAL PROTEIN
PH0634)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 11 LEU A 337
HIS A  31
HIS A  18
THR A  14
THR A  13
 None
 1.13A 2dttD-1rvkA:
undetectable
2dttE-1rvkA:
undetectable		 2dttD-1rvkA:
16.37
2dttE-1rvkA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		3 / 3 THR A 172
PRO A 181
TYR A 211
 None
 0.88A 2dxrA-1rvkA:
undetectable		 2dxrA-1rvkA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		3 / 3 ASN A 311
TYR A 345
SER A 350
 None
 0.94A 2gvcB-1rvkA:
0.4		 2gvcB-1rvkA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		3 / 3 ASN A 311
TYR A 345
SER A 350
 None
 0.92A 2gvcE-1rvkA:
0.5		 2gvcE-1rvkA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 GLY A 256
ILE A 231
ALA A 216
ASP A 206
GLU A 258
 None
None
None
MG  A 999 (-2.7A)
MG  A 999 (-2.5A)
 1.27A 2vdvE-1rvkA:
undetectable		 2vdvE-1rvkA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 11 GLY A 256
ILE A 231
ALA A 216
ASP A 206
GLU A 258
 None
None
None
MG  A 999 (-2.7A)
MG  A 999 (-2.5A)
 1.27A 2vdvF-1rvkA:
undetectable		 2vdvF-1rvkA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 7 LEU A 111
VAL A  40
THR A   4
ASP A  74
 None
 0.99A 2zaxA-1rvkA:
undetectable		 2zaxA-1rvkA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 HIS A 171
ASP A 206
GLU A 232
LEU A 332
GLY A 331
 None
MG  A 999 (-2.7A)
MG  A 999 (-3.1A)
None
None
 1.24A 2zj0A-1rvkA:
undetectable		 2zj0A-1rvkA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 HIS A 171
ASP A 206
GLU A 232
LEU A 332
GLY A 331
 None
MG  A 999 (-2.7A)
MG  A 999 (-3.1A)
None
None
 1.23A 2zj0D-1rvkA:
undetectable		 2zj0D-1rvkA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 GLY A 220
GLY A 222
LEU A 246
TYR A 211
MET A 235
 None
 1.16A 2zw9A-1rvkA:
undetectable		 2zw9A-1rvkA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 GLY A 220
GLY A 222
LEU A 246
TYR A 211
MET A 235
 None
 1.24A 2zw9B-1rvkA:
undetectable		 2zw9B-1rvkA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 LEU A 293
THR A 322
VAL A 283
VAL A 319
ILE A 124
 None
 1.02A 3bf1A-1rvkA:
undetectable
3bf1B-1rvkA:
undetectable		 3bf1A-1rvkA:
22.47
3bf1B-1rvkA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 HIS A 171
ASP A 206
GLU A 232
LEU A 332
GLY A 331
 None
MG  A 999 (-2.7A)
MG  A 999 (-3.1A)
None
None
 1.25A 3ce6A-1rvkA:
undetectable		 3ce6A-1rvkA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 HIS A 171
ASP A 206
GLU A 232
LEU A 332
GLY A 331
 None
MG  A 999 (-2.7A)
MG  A 999 (-3.1A)
None
None
 1.23A 3ce6B-1rvkA:
undetectable		 3ce6B-1rvkA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 HIS A 171
ASP A 206
GLU A 232
LEU A 332
GLY A 331
 None
MG  A 999 (-2.7A)
MG  A 999 (-3.1A)
None
None
 1.21A 3ce6C-1rvkA:
undetectable		 3ce6C-1rvkA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 HIS A 171
ASP A 206
GLU A 232
LEU A 332
GLY A 331
 None
MG  A 999 (-2.7A)
MG  A 999 (-3.1A)
None
None
 1.21A 3ce6D-1rvkA:
undetectable		 3ce6D-1rvkA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 7 ALA A  36
LEU A  38
SER A  50
THR A  52
 None
 0.94A 3d2tA-1rvkA:
undetectable		 3d2tA-1rvkA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 6 ALA A  36
LEU A  38
SER A  50
THR A  52
 None
 0.89A 3d2tB-1rvkA:
undetectable		 3d2tB-1rvkA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 7 LEU A 111
VAL A  40
THR A   4
ASP A  74
 None
 1.00A 3fwgB-1rvkA:
undetectable		 3fwgB-1rvkA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 TYR A 153
GLY A 154
ALA A 192
HIS A 171
CYH A 139
 None
 1.49A 3s8pA-1rvkA:
undetectable		 3s8pA-1rvkA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 TYR A 153
GLY A 154
ALA A 192
HIS A 171
CYH A 139
 None
 1.48A 3s8pB-1rvkA:
undetectable		 3s8pB-1rvkA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 6 SER A 350
LEU A 367
MET A 314
THR A 312
 None
 1.30A 3thrB-1rvkA:
undetectable		 3thrB-1rvkA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 TYR A 153
GLY A 154
ALA A 192
HIS A 171
CYH A 139
 None
 1.48A 4bupA-1rvkA:
undetectable		 4bupA-1rvkA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 TYR A 153
GLY A 154
ALA A 192
HIS A 171
CYH A 139
 None
 1.46A 4bupB-1rvkA:
undetectable		 4bupB-1rvkA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 5 HIS A 171
TYR A 339
GLY A 331
SER A 136
 None
 1.30A 4fu8A-1rvkA:
undetectable		 4fu8A-1rvkA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 5 THR A 172
VAL A 177
PRO A 181
TYR A 211
 None
 1.14A 4grkA-1rvkA:
undetectable		 4grkA-1rvkA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 6 ALA A  36
LEU A  38
SER A  50
THR A  52
 None
 1.02A 4i89A-1rvkA:
undetectable		 4i89A-1rvkA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 THR A 100
LEU A  70
VAL A  66
ASP A 105
 None
 0.87A 4l4aA-1rvkA:
0.0		 4l4aA-1rvkA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 8 THR A 100
LEU A  70
VAL A  66
ASP A 105
 None
 0.82A 4l4dA-1rvkA:
0.0		 4l4dA-1rvkA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 TYR A 328
GLY A 282
GLU A 258
ALA A 320
HIS A 317
 None
None
MG  A 999 (-2.5A)
None
None
 1.12A 4wcxC-1rvkA:
10.9		 4wcxC-1rvkA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 6 ALA A  36
LEU A  38
SER A  50
THR A  52
 None
 1.01A 5bojA-1rvkA:
undetectable		 5bojA-1rvkA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 TYR A 153
GLY A 154
ALA A 192
HIS A 171
CYH A 139
 None
 1.45A 5cprB-1rvkA:
undetectable		 5cprB-1rvkA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 VAL A 308
HIS A 309
ALA A 313
VAL A 318
LEU A 367
 None
 0.96A 5igtA-1rvkA:
undetectable		 5igtA-1rvkA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 6 VAL A   8
ARG A  12
ILE A 376
PHE A  11
 None
 0.93A 5jw1B-1rvkA:
undetectable		 5jw1B-1rvkA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 6 ALA A  36
LEU A  38
SER A  50
THR A  52
 None
 1.00A 5l4iA-1rvkA:
undetectable		 5l4iA-1rvkA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 GLY A 288
PHE A  51
HIS A 317
ARG A  78
LEU A 367
 None
 1.33A 5lsuB-1rvkA:
undetectable		 5lsuB-1rvkA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NR3_A_95EA401_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3B)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 7 ILE A 124
TRP A 109
ASP A 105
SER A  50
 None
 1.44A 5nr3A-1rvkA:
0.0		 5nr3A-1rvkA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		3 / 3 GLU A 269
HIS A 266
ARG A 267
 None
 0.96A 5uunA-1rvkA:
undetectable		 5uunA-1rvkA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 7 GLY A 331
LEU A 332
LEU A 143
GLY A 135
LEU A 160
 None
 1.39A 5vkqA-1rvkA:
undetectable
5vkqB-1rvkA:
undetectable		 5vkqA-1rvkA:
11.99
5vkqB-1rvkA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		5 / 12 PRO A  54
ALA A  53
GLU A  63
PHE A  65
VAL A   6
 None
 1.20A 5x6yA-1rvkA:
undetectable		 5x6yA-1rvkA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1rvk ISOMERASE/LACTONIZIN
G ENZYME
(Agrobacterium
fabrum) 		4 / 5 LEU A 160
TYR A 165
ILE A 278
GLY A 331
 None
 0.99A 6hd6A-1rvkA:
undetectable		 6hd6A-1rvkA:
14.47