SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rw0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1rw0 CONSERVED
HYPOTHETICAL PROTEIN
(Salmonella
enterica) 		5 / 10 LEU A  36
LEU A  54
ILE A  23
THR A  21
THR A 233
 None
 1.38A 1i18A-1rw0A:
undetectable
1i18B-1rw0A:
undetectable		 1i18A-1rw0A:
19.15
1i18B-1rw0A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1rw0 CONSERVED
HYPOTHETICAL PROTEIN
(Salmonella
enterica) 		5 / 10 THR A 233
LEU A  36
LEU A  54
ILE A  23
THR A  21
 None
 1.39A 1i18A-1rw0A:
undetectable
1i18B-1rw0A:
undetectable		 1i18A-1rw0A:
19.15
1i18B-1rw0A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 1rw0 CONSERVED
HYPOTHETICAL PROTEIN
(Salmonella
enterica) 		4 / 8 SER A  91
PHE A 112
ALA A 151
LEU A 202
 None
 1.10A 2bxkA-1rw0A:
undetectable		 2bxkA-1rw0A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 1rw0 CONSERVED
HYPOTHETICAL PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A  11
ALA A  17
GLY A 213
THR A 104
VAL A 102
 None
 1.02A 3c6gA-1rw0A:
undetectable		 3c6gA-1rw0A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1rw0 CONSERVED
HYPOTHETICAL PROTEIN
(Salmonella
enterica) 		4 / 8 LEU A 135
ARG A 199
SER A 238
GLY A 212
 None
 1.08A 3hcrA-1rw0A:
undetectable		 3hcrA-1rw0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 1rw0 CONSERVED
HYPOTHETICAL PROTEIN
(Salmonella
enterica) 		4 / 7 PRO A   7
SER A  20
ASP A  32
THR A 233
 None
 1.25A 4uacA-1rw0A:
undetectable		 4uacA-1rw0A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 1rw0 CONSERVED
HYPOTHETICAL PROTEIN
(Salmonella
enterica) 		5 / 12 CYH A 113
ALA A 151
LEU A 111
ALA A  17
VAL A  15
 None
 1.13A 4x1iB-1rw0A:
undetectable		 4x1iB-1rw0A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1rw0 CONSERVED
HYPOTHETICAL PROTEIN
(Salmonella
enterica) 		4 / 6 LEU A  34
THR A 104
LEU A  54
GLU A  48
 None
 0.96A 5tudD-1rw0A:
undetectable		 5tudD-1rw0A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1rw0 CONSERVED
HYPOTHETICAL PROTEIN
(Salmonella
enterica) 		3 / 3 TYR A  92
ARG A  77
THR A  79
 None
 0.77A 5z84J-1rw0A:
0.0		 5z84J-1rw0A:
11.52