SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ry4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1ry4 CG5884-PA
(Drosophila
melanogaster) 		5 / 8 THR A 209
GLY A 210
GLY A 173
LEU A 205
GLY A 203
 None
 1.41A 1jhvA-1ry4A:
undetectable		 1jhvA-1ry4A:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 1ry4 CG5884-PA
(Drosophila
melanogaster) 		4 / 5 ASP A 216
THR A 209
LEU A 211
LEU A 212
 None
 1.06A 1u18B-1ry4A:
undetectable		 1u18B-1ry4A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_B_SALB104_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1ry4 CG5884-PA
(Drosophila
melanogaster) 		5 / 9 VAL A 249
VAL A 234
MET A 238
ILE A 176
ILE A 195
 None
 1.46A 3hgxB-1ry4A:
undetectable		 3hgxB-1ry4A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 1ry4 CG5884-PA
(Drosophila
melanogaster) 		3 / 3 VAL A 145
ALA A 147
PHE A 142
 None
 0.81A 4olbA-1ry4A:
undetectable		 4olbA-1ry4A:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 1ry4 CG5884-PA
(Drosophila
melanogaster) 		4 / 5 GLY A 228
ALA A 227
GLY A 194
PRO A 193
 None
 0.98A 4u9uB-1ry4A:
undetectable		 4u9uB-1ry4A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1ry4 CG5884-PA
(Drosophila
melanogaster) 		3 / 3 VAL A 145
ALA A 147
PHE A 142
 None
 0.88A 4w5nA-1ry4A:
undetectable		 4w5nA-1ry4A:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1ry4 CG5884-PA
(Drosophila
melanogaster) 		3 / 3 VAL A 145
ALA A 147
PHE A 142
 None
 0.81A 4z4iA-1ry4A:
undetectable		 4z4iA-1ry4A:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1ry4 CG5884-PA
(Drosophila
melanogaster) 		3 / 3 VAL A 145
ALA A 147
PHE A 142
 None
 0.84A 5js1A-1ry4A:
undetectable		 5js1A-1ry4A:
10.27