SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ryt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1ryt RUBRERYTHRIN
(Desulfovibrio
vulgaris) 		5 / 11 GLU A  53
HIS A  56
GLU A  94
ILE A 124
GLU A 128
 FE  A 600 ( 2.4A)
None
FE  A 600 (-1.9A)
None
FE  A 601 ( 2.3A)
 0.81A 1rnrA-1rytA:
9.7		 1rnrA-1rytA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1ryt RUBRERYTHRIN
(Desulfovibrio
vulgaris) 		5 / 12 GLU A  53
HIS A  56
GLU A  94
ILE A 124
GLU A 128
 FE  A 600 ( 2.4A)
None
FE  A 600 (-1.9A)
None
FE  A 601 ( 2.3A)
 0.83A 1rnrB-1rytA:
9.6		 1rnrB-1rytA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 1ryt RUBRERYTHRIN
(Desulfovibrio
vulgaris) 		4 / 6 PHE A  46
ARG A 134
GLN A  52
LEU A  60
 None
 1.26A 2nyrA-1rytA:
undetectable		 2nyrA-1rytA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1ryt RUBRERYTHRIN
(Desulfovibrio
vulgaris) 		4 / 7 ALA A  57
TYR A 102
ILE A 124
HIS A 131
 None
None
None
FE  A 600 (-3.5A)
 1.16A 2zm7A-1rytA:
undetectable		 2zm7A-1rytA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 1ryt RUBRERYTHRIN
(Desulfovibrio
vulgaris) 		3 / 3 LYS A 181
PRO A 180
LEU A 173
 None
 0.71A 3tpxE-1rytA:
undetectable		 3tpxE-1rytA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 1ryt RUBRERYTHRIN
(Desulfovibrio
vulgaris) 		3 / 3 ASP A  51
ARG A  24
ASP A  44
 None
 0.83A 4fp9A-1rytA:
undetectable		 4fp9A-1rytA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 1ryt RUBRERYTHRIN
(Desulfovibrio
vulgaris) 		3 / 3 ASP A  51
ARG A  24
ASP A  44
 None
 0.77A 4fp9C-1rytA:
undetectable		 4fp9C-1rytA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 1ryt RUBRERYTHRIN
(Desulfovibrio
vulgaris) 		3 / 3 ASP A  51
ARG A  24
ASP A  44
 None
 0.77A 4fp9F-1rytA:
undetectable		 4fp9F-1rytA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 1ryt RUBRERYTHRIN
(Desulfovibrio
vulgaris) 		5 / 12 ILE A 142
GLU A 144
GLY A 145
ARG A 146
GLU A 172
 None
 1.32A 5fhzD-1rytA:
undetectable		 5fhzD-1rytA:
18.34