SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ryy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 11 TYR A 595
PHE A 597
VAL A 545
ILE A 616
TYR A 470
 None
 1.28A 1fkjA-1ryyA:
undetectable		 1fkjA-1ryyA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 12 TYR A 160
TYR A  91
LEU A  90
SER A 156
PHE A 209
 None
 1.35A 1fmlA-1ryyA:
undetectable		 1fmlA-1ryyA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		3 / 3 TRP A 332
VAL A 364
TRP A 349
 None
 1.31A 1gmkC-1ryyA:
undetectable
1gmkD-1ryyA:
undetectable		 1gmkC-1ryyA:
7.02
1gmkD-1ryyA:
7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		4 / 8 ARG A 523
ASN A 603
ASP A 425
LYS A 427
 None
 1.22A 1hwiB-1ryyA:
0.6		 1hwiB-1ryyA:
19.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		8 / 8 TYR A 112
ARG A 117
TYR A 154
GLU A 207
GLN A 257
HIS A 370
SER A 371
TYR A 375
 None
 0.49A 1nx9A-1ryyA:
60.9		 1nx9A-1ryyA:
99.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		8 / 8 TYR A 112
ARG A 117
TYR A 154
GLU A 207
GLN A 257
HIS A 370
SER A 371
TYR A 375
 None
 0.49A 1nx9B-1ryyA:
61.0		 1nx9B-1ryyA:
99.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		8 / 8 TYR A 112
ARG A 117
TYR A 154
GLU A 207
GLN A 257
HIS A 370
SER A 371
TYR A 375
 None
 0.48A 1nx9C-1ryyA:
60.9		 1nx9C-1ryyA:
99.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		8 / 8 TYR A 112
ARG A 117
TYR A 154
GLU A 207
GLN A 257
HIS A 370
SER A 371
TYR A 375
 None
 0.47A 1nx9D-1ryyA:
60.9		 1nx9D-1ryyA:
99.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 12 LEU A 532
GLY A 466
GLY A 653
ILE A 650
LEU A 587
 None
 1.03A 1p91B-1ryyA:
undetectable		 1p91B-1ryyA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		3 / 3 GLU A 333
TRP A 368
LYS A 153
 None
 1.30A 1qu2A-1ryyA:
undetectable		 1qu2A-1ryyA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 12 GLY A 263
GLY A 262
ILE A 267
ASP A 266
GLY A 292
 None
 0.98A 1sqfA-1ryyA:
undetectable		 1sqfA-1ryyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		4 / 8 THR A 447
LEU A 457
VAL A 524
VAL A 664
 None
 0.72A 1t86A-1ryyA:
undetectable		 1t86A-1ryyA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 12 GLY A 158
GLN A 157
MET A  84
VAL A  82
MET A  81
 None
 1.48A 1z95A-1ryyA:
undetectable		 1z95A-1ryyA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		4 / 7 GLY A 377
THR A 389
TYR A 421
ASN A 376
 None
 1.00A 2g70A-1ryyA:
undetectable		 2g70A-1ryyA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		4 / 7 GLY A 377
THR A 389
TYR A 421
ASN A 376
 None
 0.98A 2g70B-1ryyA:
undetectable		 2g70B-1ryyA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		3 / 3 SER A 537
HIS A 651
ASP A 453
 None
 0.85A 2oxtA-1ryyA:
undetectable		 2oxtA-1ryyA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		4 / 7 LEU A 497
LEU A 623
ILE A 572
MET A 570
 None
 0.97A 2qqdA-1ryyA:
undetectable
2qqdE-1ryyA:
undetectable		 2qqdA-1ryyA:
7.41
2qqdE-1ryyA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		3 / 3 GLN A 157
THR A  92
TRP A 187
 None
 1.12A 2rctA-1ryyA:
0.0		 2rctA-1ryyA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		4 / 7 LEU A 216
PRO A 326
LEU A 352
ALA A 348
 None
 1.01A 2vcvG-1ryyA:
undetectable		 2vcvG-1ryyA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		4 / 6 PRO A 435
ILE A 346
ASN A 603
LEU A 336
 None
 1.26A 2wekB-1ryyA:
2.2		 2wekB-1ryyA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 8 PHE A 459
THR A 515
LEU A 518
LEU A 449
VAL A 524
 None
 1.27A 2zujA-1ryyA:
undetectable		 2zujA-1ryyA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		6 / 12 ALA A 214
ALA A 226
GLU A 207
THR A  92
ILE A 150
THR A 184
 None
 1.46A 3dl9B-1ryyA:
0.0		 3dl9B-1ryyA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8F_A_DM1A127_1
(TRANSCRIPTIONAL
REGULATOR, PADR-LIKE
FAMILY)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 10 ALA A 418
ALA A 601
MET A 365
TRP A 349
ASP A 354
 None
 1.23A 3f8fA-1ryyA:
0.0
3f8fB-1ryyA:
0.0		 3f8fA-1ryyA:
11.98
3f8fB-1ryyA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		4 / 4 ARG A 483
ASP A 271
ASP A 273
PRO A 484
 None
 1.34A 3fgrB-1ryyA:
0.0		 3fgrB-1ryyA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		3 / 3 ALA A 124
ARG A  73
LYS A  71
 None
 0.97A 3kp5B-1ryyA:
0.3		 3kp5B-1ryyA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		3 / 3 ARG A 369
LEU A 380
THR A 389
 None
 0.66A 3oxcA-1ryyA:
0.0		 3oxcA-1ryyA:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		3 / 3 HIS A 391
ARG A 395
GLU A 140
 None
 1.18A 3qf1A-1ryyA:
undetectable		 3qf1A-1ryyA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		3 / 3 ASP A 149
GLY A 116
TYR A  91
 None
 0.76A 3w9tC-1ryyA:
undetectable		 3w9tC-1ryyA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		3 / 3 ASP A 149
GLY A 116
TYR A  91
 None
 0.76A 3w9tG-1ryyA:
undetectable		 3w9tG-1ryyA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		4 / 7 THR A 447
LEU A 457
VAL A 524
VAL A 664
 None
 0.73A 4cp4A-1ryyA:
undetectable		 4cp4A-1ryyA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 12 GLU A 228
PHE A 398
LEU A 317
GLY A 208
ARG A 145
 None
 1.37A 4djeA-1ryyA:
undetectable		 4djeA-1ryyA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 12 GLU A 228
PHE A 398
LEU A 321
GLY A 208
ARG A 145
 None
 1.37A 4djeA-1ryyA:
undetectable		 4djeA-1ryyA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 12 GLU A 228
PHE A 398
LEU A 321
GLY A 208
ARG A 145
 None
 1.40A 4djfB-1ryyA:
undetectable		 4djfB-1ryyA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		3 / 3 ARG A 394
TRP A 368
GLY A 372
 None
 0.86A 4e7cA-1ryyA:
undetectable		 4e7cA-1ryyA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		4 / 6 ASN A 171
LEU A 170
ASP A 176
GLU A 177
 None
 0.90A 4g24A-1ryyA:
undetectable		 4g24A-1ryyA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		4 / 6 ARG A 269
ALA A 488
ASP A 274
SER A 256
 None
 1.14A 4ot2A-1ryyA:
undetectable		 4ot2A-1ryyA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 12 ASP A 354
ILE A 346
ALA A 345
GLY A 526
VAL A 527
 None
 0.99A 5i73A-1ryyA:
undetectable		 5i73A-1ryyA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SVL_A_ACTA411_0
(P2X PURINOCEPTOR 3)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		4 / 5 GLN A 350
VAL A 357
ASP A 354
ASN A 361
 None
 1.27A 5svlA-1ryyA:
0.0		 5svlA-1ryyA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V9J_B_SAMB1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 12 GLY A 203
TYR A 393
ASN A 374
PHE A 138
ARG A 145
 None
 1.13A 5v9jB-1ryyA:
undetectable		 5v9jB-1ryyA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 7 GLY A 335
LEU A 336
LEU A 599
ILE A 420
LEU A 363
 None
 1.21A 5vkqA-1ryyA:
undetectable
5vkqB-1ryyA:
undetectable		 5vkqA-1ryyA:
17.94
5vkqB-1ryyA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		5 / 8 GLY A 335
LEU A 336
LEU A 599
ILE A 420
LEU A 363
 None
 1.20A 5vkqB-1ryyA:
undetectable
5vkqC-1ryyA:
undetectable		 5vkqB-1ryyA:
17.94
5vkqC-1ryyA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		3 / 3 GLY A 377
ASN A 376
ARG A 394
 None
 0.75A 5w7bD-1ryyA:
2.6		 5w7bD-1ryyA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		4 / 6 GLU A 177
ARG A 164
ASP A 149
ASP A 183
 None
 1.21A 5zw4A-1ryyA:
undetectable		 5zw4A-1ryyA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1ryy ALPHA-AMINO ACID
ESTER HYDROLASE
(Acetobacter
pasteurianus) 		3 / 3 LEU A 446
ASN A 603
LEU A 547
 None
 0.59A 6exiA-1ryyA:
3.3		 6exiA-1ryyA:
7.83