SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rz2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1rz2 CONSERVED
HYPOTHETICAL PROTEIN
BA4783
(Bacillus
anthracis) 		4 / 6 ASN A 102
ILE A 192
ASN A 134
ASN A 126
 None
 1.23A 1h7xA-1rz2A:
undetectable		 1h7xA-1rz2A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1rz2 CONSERVED
HYPOTHETICAL PROTEIN
BA4783
(Bacillus
anthracis) 		4 / 6 ASN A 102
ILE A 192
ASN A 134
ASN A 126
 None
 1.23A 1h7xB-1rz2A:
undetectable		 1h7xB-1rz2A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1rz2 CONSERVED
HYPOTHETICAL PROTEIN
BA4783
(Bacillus
anthracis) 		4 / 6 ASN A 102
ILE A 192
ASN A 134
ASN A 126
 None
 1.22A 1h7xC-1rz2A:
undetectable		 1h7xC-1rz2A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1rz2 CONSERVED
HYPOTHETICAL PROTEIN
BA4783
(Bacillus
anthracis) 		4 / 6 ASN A 102
ILE A 192
ASN A 134
ASN A 126
 None
 1.22A 1h7xD-1rz2A:
undetectable		 1h7xD-1rz2A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 1rz2 CONSERVED
HYPOTHETICAL PROTEIN
BA4783
(Bacillus
anthracis) 		3 / 3 PHE A 180
SER A 213
GLN A 210
 None
 0.94A 3smtA-1rz2A:
0.0		 3smtA-1rz2A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1rz2 CONSERVED
HYPOTHETICAL PROTEIN
BA4783
(Bacillus
anthracis) 		4 / 7 ILE A  52
VAL A 128
ILE A  96
PHE A 172
 None
 0.83A 5hieC-1rz2A:
undetectable		 5hieC-1rz2A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1rz2 CONSERVED
HYPOTHETICAL PROTEIN
BA4783
(Bacillus
anthracis) 		3 / 3 LEU A 166
THR A 135
ASN A 134
 None
 0.73A 6baaE-1rz2A:
undetectable		 6baaE-1rz2A:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1rz2 CONSERVED
HYPOTHETICAL PROTEIN
BA4783
(Bacillus
anthracis) 		3 / 3 LEU A 166
THR A 135
ASN A 134
 None
 0.73A 6baaF-1rz2A:
undetectable		 6baaF-1rz2A:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1rz2 CONSERVED
HYPOTHETICAL PROTEIN
BA4783
(Bacillus
anthracis) 		3 / 3 LEU A 166
THR A 135
ASN A 134
 None
 0.73A 6baaG-1rz2A:
undetectable		 6baaG-1rz2A:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1rz2 CONSERVED
HYPOTHETICAL PROTEIN
BA4783
(Bacillus
anthracis) 		3 / 3 LEU A 166
THR A 135
ASN A 134
 None
 0.73A 6baaH-1rz2A:
undetectable		 6baaH-1rz2A:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 1rz2 CONSERVED
HYPOTHETICAL PROTEIN
BA4783
(Bacillus
anthracis) 		3 / 3 LYS A 249
VAL A 251
ASP A 225
 None
 0.69A 6fgdA-1rz2A:
undetectable		 6fgdA-1rz2A:
19.95