SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rz6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 1rz6 CYTOCHROME C
PEROXIDASE
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 8 VAL A 204
ASN A 205
ASN A  89
GLY A 107
 None
None
HEM  A 401 (-4.4A)
None
 0.68A 1dzmA-1rz6A:
undetectable		 1dzmA-1rz6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 1rz6 CYTOCHROME C
PEROXIDASE
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 GLU A  40
LEU A 126
MET A 152
MET A 115
 None
None
None
CIT  A 502 ( 4.3A)
 1.14A 1linA-1rz6A:
undetectable		 1linA-1rz6A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)		 1rz6 CYTOCHROME C
PEROXIDASE
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 VAL A 122
LEU A 126
MET A 129
TYR A 132
GLU A  37
 None
 1.20A 1p5zB-1rz6A:
undetectable		 1p5zB-1rz6A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 1rz6 CYTOCHROME C
PEROXIDASE
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A 206
ASN A 205
GLY A 207
THR A 165
ILE A  14
 None
 1.30A 1p93A-1rz6A:
undetectable		 1p93A-1rz6A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 1rz6 CYTOCHROME C
PEROXIDASE
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A 206
ASN A 205
GLY A 208
THR A 165
ILE A  14
 None
 1.25A 1p93A-1rz6A:
undetectable		 1p93A-1rz6A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 1rz6 CYTOCHROME C
PEROXIDASE
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 ASP A 171
LEU A 174
HIS A 201
 None
None
HEM  A 402 (-3.2A)
 0.70A 1qknA-1rz6A:
undetectable		 1qknA-1rz6A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1rz6 CYTOCHROME C
PEROXIDASE
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 GLY A  60
THR A 256
ASN A 252
 None
 0.71A 3v4tD-1rz6A:
undetectable		 3v4tD-1rz6A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 1rz6 CYTOCHROME C
PEROXIDASE
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 PHE A 192
GLY A 207
ILE A 253
LEU A 299
 HEM  A 402 (-4.8A)
None
HEM  A 402 (-4.9A)
None
 0.90A 4ejjD-1rz6A:
undetectable		 4ejjD-1rz6A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1rz6 CYTOCHROME C
PEROXIDASE
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 GLU A 185
LYS A 186
LEU A 189
LEU A   3
 None
 0.75A 4wg0B-1rz6A:
undetectable
4wg0C-1rz6A:
undetectable		 4wg0B-1rz6A:
3.07
4wg0C-1rz6A:
3.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 1rz6 CYTOCHROME C
PEROXIDASE
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 5 SER A  44
SER A  45
SER A  46
SER A 116
 CIT  A 502 (-4.7A)
None
None
CIT  A 502 (-3.5A)
 0.93A 5hswA-1rz6A:
undetectable		 5hswA-1rz6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1rz6 CYTOCHROME C
PEROXIDASE
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 ARG A  42
PHE A  38
LEU A 311
 None
 0.94A 5x1bC-1rz6A:
undetectable		 5x1bC-1rz6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1rz6 CYTOCHROME C
PEROXIDASE
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 GLY A 231
PHE A 233
VAL A 235
SER A 267
 None
None
None
CIT  A 503 (-2.6A)
 0.99A 6hu9S-1rz6A:
undetectable
6hu9q-1rz6A:
0.0		 6hu9S-1rz6A:
14.85
6hu9q-1rz6A:
19.06