SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rz9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDW_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 1rz9 REP PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		5 / 10 VAL A 108
LEU A 104
VAL A  94
PHE A  63
GLU A   6
 None
 1.50A 1fdwA-1rz9A:
undetectable		 1fdwA-1rz9A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 1rz9 REP PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		3 / 3 GLN A  73
LYS A  76
VAL A  94
 None
 0.64A 2jfaB-1rz9A:
undetectable		 2jfaB-1rz9A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 1rz9 REP PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 8 LEU A  53
ARG A  61
PRO A  38
SER A  41
 None
 1.16A 2qd2A-1rz9A:
undetectable		 2qd2A-1rz9A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 1rz9 REP PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		3 / 3 LEU A  37
PRO A  38
ARG A 182
 None
 0.60A 2qd4B-1rz9A:
undetectable		 2qd4B-1rz9A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1rz9 REP PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 8 VAL A   7
VAL A 108
ILE A 111
LEU A  64
 None
 0.88A 4jq1B-1rz9A:
undetectable		 4jq1B-1rz9A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1rz9 REP PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 6 VAL A   7
VAL A 108
ILE A 111
LEU A  64
 None
 0.88A 4l1wB-1rz9A:
undetectable		 4l1wB-1rz9A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1rz9 REP PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		4 / 7 GLU A  82
PHE A  81
TYR A  87
HIS A  89
 None
 1.44A 4uciB-1rz9A:
0.0		 4uciB-1rz9A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1rz9 REP PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		5 / 9 LEU A  53
THR A  54
ASP A  57
GLY A  32
ILE A  34
 None
 1.14A 6ebpA-1rz9A:
undetectable		 6ebpA-1rz9A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1rz9 REP PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		5 / 10 LEU A  53
THR A  54
ASP A  57
GLY A  32
ILE A  34
 None
 1.14A 6ebpB-1rz9A:
undetectable		 6ebpB-1rz9A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1rz9 REP PROTEIN
(Adeno-associated
dependoparvoviru
s
B) 		5 / 10 LEU A  53
THR A  54
ASP A  57
GLY A  32
ILE A  34
 None
 1.17A 6ebpC-1rz9A:
undetectable		 6ebpC-1rz9A:
17.17