SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rzo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1rzo AGGLUTININ
(Ricinus
communis) 		5 / 10 GLY B2199
HIS B2248
THR B2193
THR B2200
ILE B2197
 None
SO4  B6002 (-3.8A)
None
None
None
 1.43A 1gtfL-1rzoB:
undetectable
1gtfV-1rzoB:
undetectable		 1gtfL-1rzoB:
11.89
1gtfV-1rzoB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 1rzo AGGLUTININ
(Ricinus
communis) 		4 / 5 LEU B2161
TRP B2173
ILE B2181
ASN B2226
 None
 1.49A 4i00A-1rzoB:
undetectable		 4i00A-1rzoB:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1rzo AGGLUTININ
(Ricinus
communis) 		5 / 10 GLY B2199
HIS B2248
THR B2193
THR B2200
ILE B2197
 None
SO4  B6002 (-3.8A)
None
None
None
 1.40A 5eeuR-1rzoB:
undetectable
5eeuS-1rzoB:
undetectable		 5eeuR-1rzoB:
11.89
5eeuS-1rzoB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1rzo AGGLUTININ
(Ricinus
communis) 		5 / 10 GLY B2199
HIS B2248
THR B2193
THR B2200
ILE B2197
 None
SO4  B6002 (-3.8A)
None
None
None
 1.40A 5eevR-1rzoB:
undetectable
5eevS-1rzoB:
undetectable		 5eevR-1rzoB:
11.89
5eevS-1rzoB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1rzo AGGLUTININ
(Ricinus
communis) 		5 / 10 GLY B2199
HIS B2248
THR B2193
THR B2200
ILE B2197
 None
SO4  B6002 (-3.8A)
None
None
None
 1.40A 5eewR-1rzoB:
undetectable
5eewS-1rzoB:
undetectable		 5eewR-1rzoB:
11.89
5eewS-1rzoB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1rzo AGGLUTININ
(Ricinus
communis) 		5 / 10 GLY B2199
HIS B2248
THR B2193
THR B2200
ILE B2197
 None
SO4  B6002 (-3.8A)
None
None
None
 1.40A 5eexR-1rzoB:
undetectable
5eexS-1rzoB:
undetectable		 5eexR-1rzoB:
11.89
5eexS-1rzoB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1rzo AGGLUTININ
(Ricinus
communis) 		5 / 10 GLY B2199
HIS B2248
THR B2193
THR B2200
ILE B2197
 None
SO4  B6002 (-3.8A)
None
None
None
 1.40A 5eeyR-1rzoB:
undetectable
5eeyS-1rzoB:
undetectable		 5eeyR-1rzoB:
11.89
5eeyS-1rzoB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1rzo AGGLUTININ
(Ricinus
communis) 		5 / 10 GLY B2199
HIS B2248
THR B2193
THR B2200
ILE B2197
 None
SO4  B6002 (-3.8A)
None
None
None
 1.40A 5eezR-1rzoB:
undetectable
5eezS-1rzoB:
undetectable		 5eezR-1rzoB:
11.89
5eezS-1rzoB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1rzo AGGLUTININ
(Ricinus
communis) 		5 / 10 GLY B2199
HIS B2248
THR B2193
THR B2200
ILE B2197
 None
SO4  B6002 (-3.8A)
None
None
None
 1.40A 5ef0R-1rzoB:
undetectable
5ef0S-1rzoB:
undetectable		 5ef0R-1rzoB:
11.89
5ef0S-1rzoB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1rzo AGGLUTININ
(Ricinus
communis) 		5 / 10 GLY B2199
HIS B2248
THR B2193
THR B2200
ILE B2197
 None
SO4  B6002 (-3.8A)
None
None
None
 1.40A 5ef1R-1rzoB:
undetectable
5ef1S-1rzoB:
undetectable		 5ef1R-1rzoB:
11.89
5ef1S-1rzoB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1rzo AGGLUTININ
(Ricinus
communis) 		5 / 10 GLY B2199
HIS B2248
THR B2193
THR B2200
ILE B2197
 None
SO4  B6002 (-3.8A)
None
None
None
 1.40A 5ef2R-1rzoB:
undetectable
5ef2S-1rzoB:
undetectable		 5ef2R-1rzoB:
11.89
5ef2S-1rzoB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1rzo AGGLUTININ
(Ricinus
communis) 		5 / 10 GLY B2199
HIS B2248
THR B2193
THR B2200
ILE B2197
 None
SO4  B6002 (-3.8A)
None
None
None
 1.40A 5ef3R-1rzoB:
undetectable
5ef3S-1rzoB:
undetectable		 5ef3R-1rzoB:
11.89
5ef3S-1rzoB:
11.89