SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rzv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F86_B_T44B528_1
(TRANSTHYRETIN
THR119MET VARIANT)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 4 LYS A 431
LEU A 427
ALA A 312
LEU A 308
None
1.44A 1f86B-1rzvA:
undetectable
1f86B-1rzvA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 ARG A 374
ILE A 370
VAL A 425
ALA A 310
LEU A 300
None
1.09A 1r9oA-1rzvA:
undetectable
1r9oA-1rzvA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 ARG A 374
ILE A 370
VAL A 425
ASP A 307
ALA A 310
None
1.06A 1r9oA-1rzvA:
undetectable
1r9oA-1rzvA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 LEU A 204
ILE A 234
ALA A 142
THR A 212
HIS A 242
None
1.30A 2qo4A-1rzvA:
0.0
2qo4A-1rzvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 LEU A 204
ILE A 234
ALA A 142
THR A 212
HIS A 242
None
1.30A 2qo6A-1rzvA:
undetectable
2qo6A-1rzvA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 5 PRO A 372
ILE A 306
ARG A 374
ASP A 307
None
1.40A 2rhmD-1rzvA:
0.9
2rhmD-1rzvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 LEU A 179
GLY A 202
GLY A 203
THR A 206
LEU A 181
None
1.11A 2uvnA-1rzvA:
undetectable
2uvnA-1rzvA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 7 TYR A 388
TRP A 253
VAL A 252
ILE A 248
None
1.31A 2xz5B-1rzvA:
undetectable
2xz5E-1rzvA:
undetectable
2xz5B-1rzvA:
18.24
2xz5E-1rzvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 8 ILE A 248
TYR A 388
TRP A 253
VAL A 252
None
1.29A 2xz5A-1rzvA:
undetectable
2xz5C-1rzvA:
undetectable
2xz5A-1rzvA:
18.24
2xz5C-1rzvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 8 ILE A 248
TYR A 388
TRP A 253
VAL A 252
None
1.30A 2xz5C-1rzvA:
undetectable
2xz5D-1rzvA:
undetectable
2xz5C-1rzvA:
18.24
2xz5D-1rzvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 7 ILE A 248
TYR A 388
TRP A 253
VAL A 252
None
1.28A 2xz5D-1rzvA:
undetectable
2xz5E-1rzvA:
undetectable
2xz5D-1rzvA:
18.24
2xz5E-1rzvA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 5 SER A 460
LEU A  30
GLY A 466
GLU A 462
None
1.12A 3aiaA-1rzvA:
1.4
3aiaB-1rzvA:
3.1
3aiaA-1rzvA:
17.90
3aiaB-1rzvA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 TYR A 472
GLY A 247
ASN A 246
HIS A 137
VAL A  22
None
1.32A 3f8wB-1rzvA:
undetectable
3f8wB-1rzvA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
3 / 3 GLU A   9
ASP A 138
ASP A  21
None
0.76A 3jb2A-1rzvA:
2.6
3jb2A-1rzvA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 8 GLY A 305
ILE A 297
CYH A 295
PHE A 294
None
0.90A 3ko0O-1rzvA:
undetectable
3ko0Q-1rzvA:
undetectable
3ko0O-1rzvA:
12.61
3ko0Q-1rzvA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 7 LEU A 159
HIS A 242
VAL A 233
SER A 236
None
0.94A 3r9vA-1rzvA:
undetectable
3r9vB-1rzvA:
undetectable
3r9vA-1rzvA:
22.31
3r9vB-1rzvA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 8 TYR A 388
TRP A 253
VAL A 252
ILE A 248
None
1.22A 4bqtC-1rzvA:
undetectable
4bqtD-1rzvA:
0.0
4bqtC-1rzvA:
17.90
4bqtD-1rzvA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 6 GLY A  43
VAL A  47
PRO A  45
GLY A  93
None
0.86A 4dxuA-1rzvA:
undetectable
4dxuA-1rzvA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 7 GLY A  43
VAL A  47
PRO A  45
GLY A  93
None
0.83A 4forA-1rzvA:
undetectable
4forA-1rzvA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 TYR A 472
ALA A 465
GLY A 466
ASN A 246
GLY A 247
None
1.02A 4obwD-1rzvA:
3.0
4obwD-1rzvA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 7 LEU A 430
THR A 437
ALA A 433
SER A 423
None
1.01A 4pwjB-1rzvA:
undetectable
4pwjB-1rzvA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_F_PARF500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 11 PHE A 422
SER A 373
THR A 397
GLU A 219
GLY A 399
None
1.42A 4qb9F-1rzvA:
0.0
4qb9F-1rzvA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_B_QDNB602_1
(CYTOCHROME P450 2D6)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 9 LEU A 160
PHE A 199
ALA A 141
SER A 115
ALA A 112
None
1.41A 4wnuB-1rzvA:
0.0
4wnuB-1rzvA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_A_ACTA403_0
(3C-LIKE PROTEINASE)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 5 TYR A  89
SER A   8
LEU A 114
GLN A 140
None
1.39A 4yo9A-1rzvA:
0.0
4yo9B-1rzvA:
0.0
4yo9A-1rzvA:
23.27
4yo9B-1rzvA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
4 / 7 LEU A 430
THR A 437
ALA A 433
SER A 423
None
0.95A 5bojB-1rzvA:
undetectable
5bojB-1rzvA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 10 GLY A  18
HIS A 163
VAL A 213
ASN A 246
PRO A 377
None
0.75A 5vncC-1rzvA:
6.1
5vncC-1rzvA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
6 / 10 VAL A 213
ASN A 246
LYS A 304
GLU A 376
PRO A 377
GLY A 379
None
0.83A 5vncC-1rzvA:
6.1
5vncC-1rzvA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 ILE A  41
SER A   5
GLY A  24
ASP A  21
LEU A  19
None
1.09A 6dwnD-1rzvA:
undetectable
6dwnD-1rzvA:
10.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNE_A_ACRA602_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
9 / 12 GLY A  17
GLY A  18
VAL A  22
ASP A 138
GLN A 140
VAL A 213
ASN A 246
PRO A 377
CYH A 378
None
0.95A 6gneA-1rzvA:
42.5
6gneA-1rzvA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNE_A_ACRA602_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
6 / 12 VAL A  22
VAL A 213
ASN A 246
PRO A 377
CYH A 378
GLY A 379
None
0.62A 6gneA-1rzvA:
42.5
6gneA-1rzvA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNE_B_ACRB602_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
8 / 12 GLU A   9
GLY A  17
GLY A  18
VAL A  22
ASP A 138
GLN A 140
VAL A 213
ASN A 246
None
0.66A 6gneB-1rzvA:
31.4
6gneB-1rzvA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNE_B_ACRB602_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
8 / 12 GLY A  17
GLY A  18
VAL A  22
ASP A 138
GLN A 140
VAL A 213
ASN A 246
PRO A 377
None
0.82A 6gneB-1rzvA:
31.4
6gneB-1rzvA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNE_B_ACRB602_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 VAL A  22
VAL A 213
ASN A 246
PRO A 377
GLY A 379
None
0.65A 6gneB-1rzvA:
31.4
6gneB-1rzvA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNF_A_QPSA602_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 VAL A  22
ASN A 246
GLU A 376
PRO A 377
GLY A 379
None
0.66A 6gnfA-1rzvA:
40.7
6gnfA-1rzvA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNF_A_QPSA602_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 VAL A  22
ASP A 103
ASP A 138
PHE A 167
ASN A 246
None
0.63A 6gnfA-1rzvA:
40.7
6gnfA-1rzvA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNF_A_QPSA602_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 VAL A  22
ASP A 138
PHE A 167
ASN A 246
PRO A 377
None
0.88A 6gnfA-1rzvA:
40.7
6gnfA-1rzvA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNF_A_QPSA602_2
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
6 / 9 THR A  16
GLY A  17
GLY A  18
HIS A 163
VAL A 213
CYH A 378
None
0.75A 6gnfA-1rzvA:
40.7
6gnfA-1rzvA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNF_A_QPSA602_2
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
7 / 9 THR A  16
GLY A  17
GLY A  18
TYR A  96
TRP A 139
HIS A 163
VAL A 213
None
0.60A 6gnfA-1rzvA:
40.7
6gnfA-1rzvA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNF_C_QPSC602_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
7 / 10 GLY A  18
LEU A  19
TRP A 139
HIS A 163
PHE A 167
VAL A 213
CYH A 378
None
0.95A 6gnfC-1rzvA:
41.3
6gnfC-1rzvA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNF_C_QPSC602_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
8 / 10 THR A  16
GLY A  18
LEU A  19
TYR A  96
TRP A 139
HIS A 163
PHE A 167
VAL A 213
None
0.75A 6gnfC-1rzvA:
41.3
6gnfC-1rzvA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNF_C_QPSC602_2
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 VAL A  22
ASN A 246
GLU A 376
PRO A 377
GLY A 379
None
0.65A 6gnfC-1rzvA:
41.2
6gnfC-1rzvA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
7 / 12 THR A  16
GLY A  17
LEU A  19
VAL A  22
ASP A 103
ASP A 138
ASN A 246
None
0.76A 6gngA-1rzvA:
40.5
6gngA-1rzvA:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 GLU A   9
GLY A  18
HIS A 163
VAL A 213
PRO A 377
None
0.72A 6gngA-1rzvA:
40.5
6gngA-1rzvA:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
6 / 12 GLU A   9
GLY A  18
TYR A  96
TRP A 139
HIS A 163
VAL A 213
None
0.52A 6gngA-1rzvA:
40.5
6gngA-1rzvA:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
6 / 12 THR A  16
VAL A  22
TYR A  96
TRP A 139
HIS A 163
VAL A 213
None
0.48A 6gngB-1rzvA:
40.5
6gngB-1rzvA:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 VAL A  22
HIS A 163
VAL A 213
GLU A 376
CYH A 378
None
0.72A 6gngB-1rzvA:
40.5
6gngB-1rzvA:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 VAL A  22
TRP A 139
HIS A 163
VAL A 213
CYH A 378
None
0.79A 6gngB-1rzvA:
40.5
6gngB-1rzvA:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 VAL A  22
VAL A 213
GLU A 376
CYH A 378
GLY A 379
None
0.65A 6gngB-1rzvA:
40.5
6gngB-1rzvA:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
5 / 12 GLU A   9
GLY A  17
GLY A  18
LEU A  19
PRO A 377
None
0.68A 6gngB-1rzvA:
40.5
6gngB-1rzvA:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)
1rzv GLYCOGEN SYNTHASE 1
(Agrobacterium
tumefaciens)
3 / 3 ASP A 103
ASP A 138
ASN A 246
None
0.64A 6gngB-1rzvA:
40.4
6gngB-1rzvA:
28.46