SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1rzw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1rzw PROTEIN AF2095(GR4)
(Archaeoglobus
fulgidus) 		5 / 9 ALA A  93
ILE A  29
GLY A  31
ALA A  27
ASP A  80
 None
 1.15A 4qvqK-1rzwA:
undetectable
4qvqL-1rzwA:
undetectable		 4qvqK-1rzwA:
22.56
4qvqL-1rzwA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1rzw PROTEIN AF2095(GR4)
(Archaeoglobus
fulgidus) 		5 / 9 ALA A  93
ILE A  29
GLY A  31
ALA A  27
ASP A  80
 None
 1.15A 4qvqY-1rzwA:
undetectable
4qvqZ-1rzwA:
undetectable		 4qvqY-1rzwA:
22.56
4qvqZ-1rzwA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 1rzw PROTEIN AF2095(GR4)
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 107
ALA A  68
ILE A  96
THR A  75
VAL A  94
 None
 1.03A 4xdrA-1rzwA:
undetectable		 4xdrA-1rzwA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZAU_A_YY3A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 1rzw PROTEIN AF2095(GR4)
(Archaeoglobus
fulgidus) 		5 / 8 LEU A  77
GLY A  76
VAL A  94
LEU A  58
GLY A  63
 None
 1.04A 4zauA-1rzwA:
undetectable		 4zauA-1rzwA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 1rzw PROTEIN AF2095(GR4)
(Archaeoglobus
fulgidus) 		3 / 3 GLN A  79
THR A  90
ASP A  80
 None
 0.72A 5k9dA-1rzwA:
undetectable		 5k9dA-1rzwA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 1rzw PROTEIN AF2095(GR4)
(Archaeoglobus
fulgidus) 		5 / 11 VAL A  95
ASP A  99
SER A  35
LEU A  53
THR A 108
 None
 1.39A 5tiyA-1rzwA:
undetectable		 5tiyA-1rzwA:
20.72