SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s05'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BRF_A_SORA2_0 (LIN-12 AND GLP-1 PHENOTYPE PROTEIN 1, ISOFORM A)	1s05	CYTOCHROME C-556 (Rhodopseudomonas palustris)	3 / 3	LYS A 42 LYS A 91 VAL A 93	None	0.68A	3brfA-1s05A: undetectable	3brfA-1s05A: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_D_CELD682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	1s05	CYTOCHROME C-556 (Rhodopseudomonas palustris)	4 / 5	ARG A 125 LEU A 51 ILE A 113 PHE A 89	HEM A 130 (-4.5A) None None HEM A 130 (-2.2A)	1.23A	3ln1D-1s05A: undetectable	3ln1D-1s05A: 12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MZE_A_CFXA364_2 (D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACA)	1s05	CYTOCHROME C-556 (Rhodopseudomonas palustris)	3 / 3	SER A 71 SER A 72 HIS A 121	HEM A 130 (-4.3A) None HEM A 130 (-3.6A)	0.79A	3mzeA-1s05A: 0.0	3mzeA-1s05A: 17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6D8P_A_ACTA814_0 (UNCHARACTERIZED PROTEIN)	1s05	CYTOCHROME C-556 (Rhodopseudomonas palustris)	4 / 5	GLN A 43 ASN A 15 THR A 47 LEU A 11	None HEM A 130 ( 4.0A) None None	1.37A	6d8pA-1s05A: undetectable	6d8pA-1s05A: 10.17

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3BRF_A_SORA2_0","LIN-12 AND GLP-1 PHENOTYPE PROTEIN 1, ISOFORM A","1s05","CYTOCHROME C-556","Rhodopseudomonas palustris",3,"LYS A  42;LYS A  91;VAL A  93","None","0.68A","3brfA-1s05A:undetectable","3brfA-1s05A:14.29"],["3LN1_D_CELD682_2","PROSTAGLANDIN G\/H SYNTHASE 2","1s05","CYTOCHROME C-556","Rhodopseudomonas palustris",4,"ARG A 125;LEU A  51;ILE A 113;PHE A  89","HEM A 130 (-4.5A);None;None;HEM A 130 (-2.2A)","1.23A","3ln1D-1s05A:undetectable","3ln1D-1s05A:12.28"],["3MZE_A_CFXA364_2","D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACA","1s05","CYTOCHROME C-556","Rhodopseudomonas palustris",3,"SER A  71;SER A  72;HIS A 121","HEM A 130 (-4.3A);None;HEM A 130 (-3.6A)","0.79A","3mzeA-1s05A:0.0","3mzeA-1s05A:17.63"],["6D8P_A_ACTA814_0","UNCHARACTERIZED PROTEIN","1s05","CYTOCHROME C-556","Rhodopseudomonas palustris",4,"GLN A  43;ASN A  15;THR A  47;LEU A  11","None;HEM A 130 ( 4.0A);None;None","1.37A","6d8pA-1s05A:undetectable","6d8pA-1s05A:10.17"]]