SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s1e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1s1e KV CHANNEL
INTERACTING PROTEIN
1
(Homo
sapiens) 		5 / 12 LEU A 127
VAL A 123
MET A 206
MET A 182
GLN A 200
 None
 1.00A 1kt4A-1s1eA:
undetectable		 1kt4A-1s1eA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1s1e KV CHANNEL
INTERACTING PROTEIN
1
(Homo
sapiens) 		5 / 11 LEU A 127
VAL A 123
MET A 206
MET A 182
GLN A 200
 None
 1.04A 1kt7A-1s1eA:
undetectable		 1kt7A-1s1eA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 1s1e KV CHANNEL
INTERACTING PROTEIN
1
(Homo
sapiens) 		5 / 12 LEU A 192
MET A 182
PHE A 178
TYR A 134
MET A 147
 None
 1.45A 1osvB-1s1eA:
undetectable		 1osvB-1s1eA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 1s1e KV CHANNEL
INTERACTING PROTEIN
1
(Homo
sapiens) 		4 / 8 PHE A  98
GLN A 213
TYR A  90
TYR A  78
 None
 1.34A 2aoxA-1s1eA:
undetectable		 2aoxA-1s1eA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 1s1e KV CHANNEL
INTERACTING PROTEIN
1
(Homo
sapiens) 		5 / 8 LEU A 127
VAL A 123
MET A 206
MET A 182
GLN A 200
 None
 1.15A 5nu7A-1s1eA:
undetectable		 5nu7A-1s1eA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 1s1e KV CHANNEL
INTERACTING PROTEIN
1
(Homo
sapiens) 		5 / 12 MET A 158
ILE A 154
VAL A 215
LEU A  94
LEU A 133
 None
 1.21A 5tiwA-1s1eA:
undetectable		 5tiwA-1s1eA:
24.04