SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s28'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 1s28 ORF1
(Pseudomonas
savastanoi) 		4 / 5 GLU A 124
LEU A 118
LEU A 121
LEU A 119
 None
 0.99A 1np1A-1s28A:
undetectable		 1np1A-1s28A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 1s28 ORF1
(Pseudomonas
savastanoi) 		5 / 12 LEU A  10
PHE A   7
LEU A  14
LEU A 119
VAL A  40
 None
 1.38A 2qd4A-1s28A:
undetectable		 2qd4A-1s28A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 1s28 ORF1
(Pseudomonas
savastanoi) 		5 / 12 LEU A  10
PHE A   7
LEU A  14
LEU A 119
VAL A  40
 None
 1.23A 2qd4B-1s28A:
undetectable		 2qd4B-1s28A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 1s28 ORF1
(Pseudomonas
savastanoi) 		4 / 8 ARG A 113
SER A 122
VAL A  52
VAL A 114
 SO4  A 401 (-3.3A)
None
None
None
 1.33A 2y05A-1s28A:
undetectable
2y05B-1s28A:
undetectable		 2y05A-1s28A:
17.47
2y05B-1s28A:
17.47