SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s2d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 1s2d PURINE TRANS
DEOXYRIBOSYLASE
(Lactobacillus
helveticus) 		4 / 8 TYR A 167
LEU A 114
TYR A  89
TYR A 164
 None
 1.07A 3po7A-1s2dA:
undetectable		 3po7A-1s2dA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 1s2d PURINE TRANS
DEOXYRIBOSYLASE
(Lactobacillus
helveticus) 		5 / 12 GLY A  85
GLY A  13
TYR A  89
MET A 127
VAL A 135
 None
AR4  A 101 ( 3.4A)
None
None
None
 1.17A 3t7vA-1s2dA:
undetectable		 3t7vA-1s2dA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 1s2d PURINE TRANS
DEOXYRIBOSYLASE
(Lactobacillus
helveticus) 		3 / 3 LYS A  57
ARG A  63
TRP A  67
 None
 1.33A 4i90A-1s2dA:
undetectable		 4i90A-1s2dA:
20.96