SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s2j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1s2j PEPTIDOGLYCAN
RECOGNITION PROTEIN
SA CG11709-PA
(Drosophila
melanogaster) 		4 / 7 LEU A  58
GLY A 108
ILE A 109
ILE A  74
 None
 0.78A 2aojB-1s2jA:
undetectable		 2aojB-1s2jA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1s2j PEPTIDOGLYCAN
RECOGNITION PROTEIN
SA CG11709-PA
(Drosophila
melanogaster) 		5 / 10 ALA A 128
VAL A  86
TYR A  76
ILE A 109
ILE A 112
 None
 1.35A 3retA-1s2jA:
undetectable
3retB-1s2jA:
undetectable		 3retA-1s2jA:
15.57
3retB-1s2jA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1s2j PEPTIDOGLYCAN
RECOGNITION PROTEIN
SA CG11709-PA
(Drosophila
melanogaster) 		3 / 3 ARG A  33
TRP A  92
GLY A 135
 None
 1.03A 4e7cA-1s2jA:
undetectable		 4e7cA-1s2jA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1s2j PEPTIDOGLYCAN
RECOGNITION PROTEIN
SA CG11709-PA
(Drosophila
melanogaster) 		4 / 7 ILE A  85
GLY A  84
LEU A 141
ASP A 130
 None
 0.69A 5hieB-1s2jA:
undetectable		 5hieB-1s2jA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1s2j PEPTIDOGLYCAN
RECOGNITION PROTEIN
SA CG11709-PA
(Drosophila
melanogaster) 		5 / 12 ASP A 122
LEU A 132
ALA A 128
PRO A 120
LEU A 163
 None
 1.22A 5nd4B-1s2jA:
undetectable		 5nd4B-1s2jA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 1s2j PEPTIDOGLYCAN
RECOGNITION PROTEIN
SA CG11709-PA
(Drosophila
melanogaster) 		4 / 8 GLY A 150
GLN A  31
VAL A  39
TYR A  76
 None
 0.96A 5vlmA-1s2jA:
undetectable		 5vlmA-1s2jA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1s2j PEPTIDOGLYCAN
RECOGNITION PROTEIN
SA CG11709-PA
(Drosophila
melanogaster) 		5 / 12 ASP A 122
LEU A 132
ALA A 128
PRO A 120
LEU A 163
 None
 1.08A 6b0iB-1s2jA:
undetectable		 6b0iB-1s2jA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 1s2j PEPTIDOGLYCAN
RECOGNITION PROTEIN
SA CG11709-PA
(Drosophila
melanogaster) 		5 / 12 SER A  49
LEU A 163
PHE A 111
ASP A  83
ASP A 122
 None
 1.36A 6dwnA-1s2jA:
undetectable		 6dwnA-1s2jA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1s2j PEPTIDOGLYCAN
RECOGNITION PROTEIN
SA CG11709-PA
(Drosophila
melanogaster) 		4 / 7 ILE A 109
GLU A 140
VAL A  38
TRP A 170
 None
 1.18A 6j20A-1s2jA:
undetectable		 6j20A-1s2jA:
18.39