SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s40'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 1s40 CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 4 VAL A 139
ALA A  82
LEU A  34
PHE A  47
 None
 1.07A 1q97B-1s40A:
undetectable		 1q97B-1s40A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_D_AZZD1211_1
(DEOXYNUCLEOSIDE
KINASE)		 1s40 CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 120
VAL A 139
MET A  84
ALA A  82
PHE A  49
 None
 1.24A 2jj8D-1s40A:
undetectable		 2jj8D-1s40A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_G_TFPG201_1
(PROTEIN S100-A4)		 1s40 CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		5 / 9 GLY A  79
PHE A  80
ILE A 120
CYH A 122
PHE A  31
 None
 1.40A 3ko0F-1s40A:
undetectable
3ko0G-1s40A:
undetectable		 3ko0F-1s40A:
21.32
3ko0G-1s40A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 1s40 CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		5 / 8 GLY A  79
PHE A  80
ILE A 120
CYH A 122
PHE A  31
 None
 1.49A 3ko0O-1s40A:
undetectable
3ko0Q-1s40A:
undetectable		 3ko0O-1s40A:
21.32
3ko0Q-1s40A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 1s40 CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 120
CYH A 122
PHE A  31
GLY A  79
PHE A  80
 None
 1.40A 3ko0R-1s40A:
undetectable
3ko0T-1s40A:
undetectable		 3ko0R-1s40A:
21.32
3ko0T-1s40A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1s40 CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 154
ASP A  51
THR A  53
PHE A  31
GLU A 160
 None
 1.25A 5hfjG-1s40A:
undetectable		 5hfjG-1s40A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1s40 CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 154
ASP A  51
THR A  53
PHE A  31
SER A 157
 None
 0.91A 5hfjG-1s40A:
undetectable		 5hfjG-1s40A:
21.52