SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s58'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 5 HIS A 513
GLU A 542
HIS A 517
HIS A 536
 None
 1.05A 1os2A-1s58A:
undetectable		 1os2A-1s58A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 6 HIS A 513
GLU A 542
HIS A 517
HIS A 536
 None
 0.95A 1y93A-1s58A:
undetectable		 1y93A-1s58A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		3 / 3 LYS A 429
ASP A 434
ASN A 432
 None
 1.01A 2bm9A-1s58A:
undetectable		 2bm9A-1s58A:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_D_H4BD1006_1
(HYPOTHETICAL PROTEIN
PH0634)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		5 / 10 HIS A 534
HIS A 536
HIS A 517
THR A 358
THR A 357
 None
 1.38A 2dttD-1s58A:
undetectable
2dttF-1s58A:
undetectable		 2dttD-1s58A:
11.19
2dttF-1s58A:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 6 HIS A 513
GLU A 542
HIS A 517
HIS A 536
 None
 0.91A 2ow9A-1s58A:
undetectable		 2ow9A-1s58A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 7 TYR A 186
VAL A 213
TYR A 184
TYR A 159
 None
 1.21A 2xz5B-1s58A:
undetectable
2xz5E-1s58A:
undetectable		 2xz5B-1s58A:
16.70
2xz5E-1s58A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 8 TYR A 186
VAL A 213
TYR A 184
TYR A 159
 None
 1.22A 2xz5A-1s58A:
undetectable
2xz5C-1s58A:
undetectable		 2xz5A-1s58A:
16.70
2xz5C-1s58A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 8 TYR A 186
VAL A 213
TYR A 184
TYR A 159
 None
 1.22A 2xz5C-1s58A:
undetectable
2xz5D-1s58A:
undetectable		 2xz5C-1s58A:
16.70
2xz5D-1s58A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 7 TYR A 186
VAL A 213
TYR A 184
TYR A 159
 None
 1.22A 2xz5D-1s58A:
undetectable
2xz5E-1s58A:
undetectable		 2xz5D-1s58A:
16.70
2xz5E-1s58A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 8 HIS A 421
ILE A 352
TYR A 337
ARG A 373
 None
 1.47A 3ccfB-1s58A:
undetectable		 3ccfB-1s58A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		5 / 7 LEU A 316
ALA A 351
SER A 298
THR A 347
VAL A 371
 None
 1.23A 3d2tA-1s58A:
undetectable		 3d2tA-1s58A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		5 / 10 ARG A 148
ASP A  49
LEU A 478
VAL A 128
ILE A 460
 None
 1.04A 3em4V-1s58A:
undetectable		 3em4V-1s58A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 5 HIS A 513
GLU A 542
HIS A 517
HIS A 536
 None
 0.92A 3likA-1s58A:
undetectable		 3likA-1s58A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 5 HIS A 513
GLU A 542
HIS A 517
HIS A 536
 None
 0.94A 3lkaA-1s58A:
undetectable		 3lkaA-1s58A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		3 / 3 HIS A 517
HIS A 534
HIS A 536
 None
 0.77A 3mihA-1s58A:
0.0		 3mihA-1s58A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		5 / 12 LEU A  97
TYR A 422
ALA A  29
LEU A 426
LEU A 242
 None
 1.34A 3vw1B-1s58A:
undetectable		 3vw1B-1s58A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		5 / 12 LEU A 149
LEU A  90
ILE A 123
PHE A  92
TYR A 161
 None
 1.42A 4a79B-1s58A:
undetectable		 4a79B-1s58A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 4 LEU A 316
ALA A 351
ILE A 352
LYS A 314
 None
 1.34A 4eixA-1s58A:
undetectable		 4eixA-1s58A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 7 ARG A 502
ARG A 550
PRO A 512
VAL A 509
 None
 1.24A 4klrA-1s58A:
undetectable		 4klrA-1s58A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMU_C_RFPC1401_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		5 / 12 GLN A 404
GLN A 383
HIS A 339
ASN A 350
ARG A 373
 None
 1.46A 4kmuC-1s58A:
undetectable		 4kmuC-1s58A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 6 LEU A 433
ASN A 432
PRO A 431
ARG A 329
 None
 1.45A 4yv5A-1s58A:
undetectable		 4yv5A-1s58A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 4 LEU A 149
ILE A 460
PRO A  47
LEU A  45
 None
 1.24A 5eb3A-1s58A:
undetectable		 5eb3A-1s58A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		5 / 12 TYR A 161
GLN A 451
PHE A  99
PHE A 492
ILE A 108
 None
 1.26A 5fsaB-1s58A:
undetectable		 5fsaB-1s58A:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 4 VAL A 141
VAL A 131
TYR A 481
GLN A 480
 None
 1.05A 5qggA-1s58A:
0.0		 5qggA-1s58A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 4 VAL A 141
VAL A 131
TYR A 481
GLN A 480
 None
 1.05A 5qgoA-1s58A:
undetectable		 5qgoA-1s58A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 4 VAL A 141
VAL A 131
TYR A 481
GLN A 480
 None
 1.03A 5qgpA-1s58A:
0.0		 5qgpA-1s58A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 4 VAL A 141
VAL A 131
TYR A 481
GLN A 480
 None
 1.02A 5qgqA-1s58A:
0.0		 5qgqA-1s58A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		4 / 4 VAL A 141
VAL A 131
TYR A 481
GLN A 480
 None
 1.02A 5qhbA-1s58A:
undetectable		 5qhbA-1s58A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		3 / 3 GLU A 215
HIS A 216
VAL A 213
 None
 0.81A 5trqB-1s58A:
2.3		 5trqB-1s58A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		3 / 3 GLY A 372
LEU A 544
HIS A 354
 None
 0.63A 5u63A-1s58A:
undetectable		 5u63A-1s58A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		3 / 3 GLY A 372
LEU A 544
HIS A 354
 None
 0.65A 5u63B-1s58A:
undetectable		 5u63B-1s58A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 1s58 B19 PARVOVIRUS
CAPSID
(Primate
erythroparvoviru
s
1) 		5 / 10 PRO A 462
HIS A  52
ALA A 482
GLY A 223
ILE A 126
 None
 1.30A 5vyhA-1s58A:
0.0		 5vyhA-1s58A:
20.56