SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s59'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 1s59 NUCLEOSIDE
DIPHOSPHATE KINASE
II
(Arabidopsis
thaliana) 		5 / 12 THR A  86
GLY A 198
SER A 199
VAL A  90
ILE A 195
 None
 0.96A 2b25B-1s59A:
undetectable		 2b25B-1s59A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_A_ACTA402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 1s59 NUCLEOSIDE
DIPHOSPHATE KINASE
II
(Arabidopsis
thaliana) 		4 / 5 ILE A 147
HIS A 130
HIS A 197
TYR A 131
 None
None
DGI  A1101 ( 4.9A)
None
 1.20A 5ocsA-1s59A:
undetectable		 5ocsA-1s59A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_C_ACTC402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 1s59 NUCLEOSIDE
DIPHOSPHATE KINASE
II
(Arabidopsis
thaliana) 		4 / 5 ILE A 147
HIS A 130
HIS A 197
TYR A 131
 None
None
DGI  A1101 ( 4.9A)
None
 1.20A 5ocsC-1s59A:
undetectable		 5ocsC-1s59A:
17.02