SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s5a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1s5a HYPOTHETICAL PROTEIN
YESE
(Bacillus
subtilis) 		4 / 7 TYR A  64
LEU A  70
GLY A  95
VAL A 130
 ACT  A 801 (-4.8A)
None
None
None
 0.86A 1t88A-1s5aA:
undetectable		 1t88A-1s5aA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1s5a HYPOTHETICAL PROTEIN
YESE
(Bacillus
subtilis) 		4 / 8 TYR A  64
LEU A  70
GLY A  95
VAL A 130
 ACT  A 801 (-4.8A)
None
None
None
 0.78A 2a1oA-1s5aA:
0.0		 2a1oA-1s5aA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1s5a HYPOTHETICAL PROTEIN
YESE
(Bacillus
subtilis) 		4 / 7 ALA A  89
TYR A 122
ILE A  88
ILE A 112
 None
 1.04A 2zm7A-1s5aA:
undetectable		 2zm7A-1s5aA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 1s5a HYPOTHETICAL PROTEIN
YESE
(Bacillus
subtilis) 		3 / 3 CYH A  93
PHE A  91
PHE A  73
 None
 0.79A 3cr5X-1s5aA:
undetectable		 3cr5X-1s5aA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 1s5a HYPOTHETICAL PROTEIN
YESE
(Bacillus
subtilis) 		5 / 10 THR A 114
ASN A  85
GLY A 117
ALA A   9
LYS A   8
 None
 1.33A 3pp7B-1s5aA:
undetectable		 3pp7B-1s5aA:
14.13