SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s5f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1s5f CHOLERA ENTEROTOXIN,
A CHAIN
(Vibrio
cholerae) 		4 / 7 ARG A   7
SER A  61
SER A  63
GLU A 112
 None
 0.99A 2c8aA-1s5fA:
undetectable		 2c8aA-1s5fA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1s5f CHOLERA ENTEROTOXIN,
A CHAIN
(Vibrio
cholerae) 		4 / 7 ARG A   7
SER A  61
SER A  63
GLU A 112
 None
 0.93A 2c8aB-1s5fA:
undetectable		 2c8aB-1s5fA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1s5f CHOLERA ENTEROTOXIN,
A CHAIN
(Vibrio
cholerae) 		4 / 6 ARG A   7
SER A  61
SER A  63
GLU A 112
 None
 0.97A 2c8aC-1s5fA:
undetectable		 2c8aC-1s5fA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1s5f CHOLERA ENTEROTOXIN,
A CHAIN
(Vibrio
cholerae) 		4 / 7 ARG A   7
SER A  61
SER A  63
GLU A 112
 None
 0.99A 2c8aD-1s5fA:
undetectable		 2c8aD-1s5fA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR6_A_DM2A2002_1
(ACRB)		 1s5f CHOLERA ENTEROTOXIN,
A CHAIN
(Vibrio
cholerae) 		5 / 9 SER A  19
SER A  10
GLY A 126
ILE A  88
PHE A  52
 None
 1.29A 2dr6A-1s5fA:
0.0		 2dr6A-1s5fA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 1s5f CHOLERA ENTEROTOXIN,
A CHAIN
(Vibrio
cholerae) 		3 / 3 GLY A 144
ARG A 143
TYR A 121
 None
 0.77A 2opxA-1s5fA:
undetectable		 2opxA-1s5fA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1s5f CHOLERA ENTEROTOXIN,
A CHAIN
(Vibrio
cholerae) 		5 / 12 SER A 122
TYR A 214
VAL A  60
MET A  94
TYR A 149
 None
 1.33A 3dzyD-1s5fA:
undetectable		 3dzyD-1s5fA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1s5f CHOLERA ENTEROTOXIN,
A CHAIN
(Vibrio
cholerae) 		5 / 8 GLY A 161
ALA A 158
GLY A 102
LEU A 101
VAL A 113
 None
 1.36A 3em6A-1s5fA:
undetectable		 3em6A-1s5fA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1s5f CHOLERA ENTEROTOXIN,
A CHAIN
(Vibrio
cholerae) 		4 / 6 ASN A  93
TYR A 149
TYR A 150
LEU A 153
 None
 1.17A 4f8yA-1s5fA:
undetectable
4f8yB-1s5fA:
undetectable		 4f8yA-1s5fA:
21.18
4f8yB-1s5fA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1s5f CHOLERA ENTEROTOXIN,
A CHAIN
(Vibrio
cholerae) 		4 / 7 TYR A 149
TYR A 150
LEU A 153
ASN A  93
 None
 1.17A 4f8yC-1s5fA:
undetectable
4f8yD-1s5fA:
undetectable		 4f8yC-1s5fA:
21.18
4f8yD-1s5fA:
21.18