SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s5j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 11 TYR A 459
THR A 567
VAL A 612
GLY A 611
VAL A 625
 None
 1.18A 1akdA-1s5jA:
undetectable		 1akdA-1s5jA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 10 LEU A  91
ASP A 147
VAL A 148
ILE A 102
GLY A 100
 None
 1.18A 1d4sA-1s5jA:
undetectable		 1d4sA-1s5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_A_CAMA503_0
(CYTOCHROME P450-CAM)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 9 TYR A 459
THR A 567
VAL A 612
GLY A 611
VAL A 625
 None
 1.28A 1dz8A-1s5jA:
0.0		 1dz8A-1s5jA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 12 PHE A 200
ARG A 571
VAL A 598
LEU A 215
ILE A 196
 None
 1.08A 1kqwA-1s5jA:
1.1		 1kqwA-1s5jA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 12 LEU A 387
LEU A 386
LEU A 431
VAL A 365
LEU A 356
 None
 1.08A 1s9pA-1s5jA:
undetectable		 1s9pA-1s5jA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 12 LEU A 387
LEU A 386
LEU A 431
VAL A 365
LEU A 356
 None
 1.10A 1s9pD-1s5jA:
0.1		 1s9pD-1s5jA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		3 / 3 GLU A 550
GLU A 543
LEU A 632
 None
 0.78A 1v8bB-1s5jA:
undetectable		 1v8bB-1s5jA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 8 GLY A 633
THR A 630
ALA A 631
VAL A 555
 None
 0.76A 2a1hA-1s5jA:
undetectable
2a1hB-1s5jA:
undetectable		 2a1hA-1s5jA:
19.42
2a1hB-1s5jA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 8 VAL A 555
GLY A 633
THR A 630
ALA A 631
 None
 0.76A 2a1hA-1s5jA:
undetectable
2a1hB-1s5jA:
undetectable		 2a1hA-1s5jA:
19.42
2a1hB-1s5jA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 11 TYR A 459
THR A 567
VAL A 612
GLY A 611
VAL A 625
 None
 1.27A 2a1nA-1s5jA:
undetectable		 2a1nA-1s5jA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 9 TYR A 459
THR A 567
VAL A 612
GLY A 611
VAL A 625
 None
 1.30A 2a1oB-1s5jA:
undetectable		 2a1oB-1s5jA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A68_C_RBTC8001_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
RNA POLYMERASE SIGMA
FACTOR RPOD)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 11 GLN A 599
ASP A 683
ARG A 571
PRO A 520
ILE A 606
 None
 1.39A 2a68C-1s5jA:
0.0
2a68F-1s5jA:
0.4		 2a68C-1s5jA:
22.81
2a68F-1s5jA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 10 TYR A 459
THR A 567
VAL A 612
GLY A 611
VAL A 625
 None
 1.32A 2cp4A-1s5jA:
undetectable		 2cp4A-1s5jA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA602_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 5 HIS A  86
ILE A 166
LYS A 180
ASP A  82
 None
 1.20A 2f7fA-1s5jA:
0.0		 2f7fA-1s5jA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 8 ILE A 230
ASP A 261
LEU A 263
GLY A 259
 None
 0.93A 2tsrB-1s5jA:
undetectable		 2tsrB-1s5jA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 12 ILE A  77
PHE A 573
TYR A 578
ALA A 211
LEU A 186
 None
 1.27A 2x2nD-1s5jA:
0.3		 2x2nD-1s5jA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 12 PHE A 423
LEU A 427
ARG A 600
ALA A 369
PHE A 370
 None
 1.46A 3apxA-1s5jA:
undetectable		 3apxA-1s5jA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 6 GLY A 505
ALA A 504
LEU A 652
PRO A 503
 None
 0.99A 3bgdA-1s5jA:
undetectable		 3bgdA-1s5jA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 8 TYR A 460
ASN A 160
LYS A 157
PRO A 138
 None
None
SO4  A 883 (-4.5A)
SO4  A 883 (-4.4A)
 1.39A 3bjwD-1s5jA:
undetectable		 3bjwD-1s5jA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 12 VAL A 309
TYR A 306
LEU A 257
TYR A 331
ILE A 255
 None
 1.36A 3frqA-1s5jA:
undetectable		 3frqA-1s5jA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		3 / 3 MET A 172
MET A 429
PHE A 218
 None
 1.34A 3gn8A-1s5jA:
undetectable		 3gn8A-1s5jA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 12 LEU A  53
LEU A  69
ALA A  79
ASP A  59
ASP A  57
 None
 1.14A 3gwuA-1s5jA:
undetectable		 3gwuA-1s5jA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		3 / 3 ILE A 120
PHE A 128
HIS A 463
 None
SO4  A 891 ( 4.3A)
None
 0.70A 3h0aA-1s5jA:
0.0		 3h0aA-1s5jA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 7 GLU A 627
VAL A 629
VAL A 533
ALA A 622
 None
 1.05A 3kp6B-1s5jA:
1.5		 3kp6B-1s5jA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		3 / 3 SER A 390
ASP A 380
ASN A 378
 None
 0.98A 3lslA-1s5jA:
undetectable
3lslD-1s5jA:
undetectable		 3lslA-1s5jA:
15.90
3lslD-1s5jA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 9 LEU A 319
ILE A 302
PRO A 337
ILE A 338
ILE A 322
 None
 0.88A 3s56B-1s5jA:
undetectable		 3s56B-1s5jA:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 5 GLU A 763
GLY A 760
TYR A 762
GLU A 863
 None
 1.35A 3w9tA-1s5jA:
undetectable		 3w9tA-1s5jA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 5 GLU A 763
GLY A 760
TYR A 762
GLU A 863
 None
 1.35A 3w9tC-1s5jA:
undetectable		 3w9tC-1s5jA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 5 GLU A 763
GLY A 760
TYR A 762
GLU A 863
 None
 1.34A 3w9tD-1s5jA:
undetectable		 3w9tD-1s5jA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 5 GLU A 763
GLY A 760
TYR A 762
GLU A 863
 None
 1.34A 3w9tG-1s5jA:
undetectable		 3w9tG-1s5jA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 6 LEU A 418
LEU A 310
ILE A 354
MET A 429
 None
 0.96A 4do3B-1s5jA:
undetectable		 4do3B-1s5jA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 5 LEU A 329
ARG A 325
ILE A 253
ASN A 272
 None
 1.30A 4i00A-1s5jA:
undetectable		 4i00A-1s5jA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 8 ALA A 151
PRO A 149
GLU A 474
LEU A 472
 None
 0.93A 4jjkA-1s5jA:
undetectable		 4jjkA-1s5jA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_A_GBMA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 11 TYR A 578
LEU A 594
TYR A 595
LEU A 188
LEU A 186
 None
 1.26A 4yvpA-1s5jA:
undetectable		 4yvpA-1s5jA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 12 TYR A 578
LEU A 594
TYR A 595
LEU A 188
LEU A 186
 None
 1.30A 4yvpB-1s5jA:
undetectable		 4yvpB-1s5jA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 12 GLY A 171
THR A 220
ILE A 443
LYS A  68
LEU A  54
 None
 1.17A 5bw4A-1s5jA:
undetectable		 5bw4A-1s5jA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		3 / 3 MET A 210
GLN A 209
ARG A 208
 None
 1.06A 5ewzB-1s5jA:
2.5		 5ewzB-1s5jA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 7 ILE A 416
ILE A 230
ASN A 378
PHE A 317
 None
 0.94A 5hieC-1s5jA:
undetectable		 5hieC-1s5jA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_D_Z80D401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 9 ILE A 102
VAL A  92
THR A 131
ASP A  97
ILE A 114
 None
 1.45A 5lg3D-1s5jA:
2.3		 5lg3D-1s5jA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		3 / 3 MET A 210
GLN A 209
ARG A 208
 None
 1.02A 5m35B-1s5jA:
2.2		 5m35B-1s5jA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		3 / 3 MET A 210
GLN A 209
ARG A 208
 None
 1.01A 5m36A-1s5jA:
2.6		 5m36A-1s5jA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		3 / 3 MET A 210
GLN A 209
ARG A 208
 None
 1.05A 6fn9A-1s5jA:
2.3		 6fn9A-1s5jA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		3 / 3 MET A 210
GLN A 209
ARG A 208
 None
 1.04A 6fnaB-1s5jA:
0.0		 6fnaB-1s5jA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		3 / 3 MET A 210
GLN A 209
ARG A 208
 None
 1.05A 6fnbA-1s5jA:
2.1		 6fnbA-1s5jA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		4 / 7 TYR A 306
VAL A 433
ILE A 354
GLY A 262
 None
 0.84A 6hd6B-1s5jA:
undetectable		 6hd6B-1s5jA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 12 VAL A 565
ILE A 566
TYR A 459
TYR A 123
ILE A 535
 None
 1.29A 6mkeA-1s5jA:
undetectable
6mkeD-1s5jA:
undetectable		 6mkeA-1s5jA:
6.17
6mkeD-1s5jA:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 1s5j DNA POLYMERASE I
(Sulfolobus
solfataricus) 		5 / 12 ILE A 232
LEU A 303
GLY A 314
PHE A 317
ALA A 229
 None
 1.05A 6r2eE-1s5jA:
0.0		 6r2eE-1s5jA:
15.85