SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 1s79 LUPUS LA PROTEIN
(Homo
sapiens) 		4 / 7 ARG A 111
VAL A 108
ASN A 139
ASP A 159
 None
 1.30A 1hwiC-1s79A:
undetectable		 1hwiC-1s79A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 1s79 LUPUS LA PROTEIN
(Homo
sapiens) 		4 / 7 ARG A 111
VAL A 108
ASN A 139
ASP A 159
 None
 1.31A 1hwiD-1s79A:
undetectable		 1hwiD-1s79A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 1s79 LUPUS LA PROTEIN
(Homo
sapiens) 		5 / 9 PHE A 118
LEU A 131
VAL A 156
LEU A 180
ILE A 115
 None
 1.12A 3tbgD-1s79A:
undetectable		 3tbgD-1s79A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1s79 LUPUS LA PROTEIN
(Homo
sapiens) 		3 / 3 ASP A 107
ASN A 110
ASP A 186
 None
 0.84A 5vopA-1s79A:
undetectable		 5vopA-1s79A:
17.91