SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)
1s7h YKOF
(Bacillus
subtilis)
4 / 6 PHE A  59
LEU A 187
VAL A 185
VAL A 170
None
1.14A 1dz4A-1s7hA:
undetectable
1dz4A-1s7hA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)
1s7h YKOF
(Bacillus
subtilis)
4 / 6 PHE A  59
LEU A 187
VAL A 185
VAL A 170
None
1.11A 1dz4B-1s7hA:
0.0
1dz4B-1s7hA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)
1s7h YKOF
(Bacillus
subtilis)
4 / 8 PHE A  59
LEU A 187
VAL A 185
VAL A 170
None
1.09A 1o76B-1s7hA:
undetectable
1o76B-1s7hA:
17.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SBR_A_VIBA501_1
(YKOF)
1s7h YKOF
(Bacillus
subtilis)
8 / 8 PHE A  15
SER A  16
LEU A  17
ILE A  25
ILE A  28
LYS A  29
THR A  44
THR A  49
None
0.46A 1sbrA-1s7hA:
33.9
1sbrA-1s7hA:
99.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SBR_A_VIBA502_1
(YKOF)
1s7h YKOF
(Bacillus
subtilis)
5 / 6 PHE A 119
ALA A 120
LEU A 121
ILE A 133
SER A 154
None
0.38A 1sbrA-1s7hA:
33.9
1sbrB-1s7hA:
33.9
1sbrA-1s7hA:
99.00
1sbrB-1s7hA:
99.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SBR_B_VIBB503_1
(YKOF)
1s7h YKOF
(Bacillus
subtilis)
7 / 7 PHE A  15
SER A  16
ILE A  25
ILE A  28
LYS A  29
THR A  44
THR A  49
None
0.84A 1sbrB-1s7hA:
33.9
1sbrB-1s7hA:
99.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SBR_B_VIBB504_1
(YKOF)
1s7h YKOF
(Bacillus
subtilis)
4 / 6 PHE A 119
LEU A 121
ILE A 133
SER A 154
None
0.38A 1sbrA-1s7hA:
33.9
1sbrB-1s7hA:
33.9
1sbrA-1s7hA:
99.00
1sbrB-1s7hA:
99.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)
1s7h YKOF
(Bacillus
subtilis)
4 / 5 PHE A  59
LEU A 187
VAL A 185
VAL A 170
None
1.14A 1t88B-1s7hA:
0.0
1t88B-1s7hA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)
1s7h YKOF
(Bacillus
subtilis)
4 / 4 ASP A 100
ASP A  56
ASP A  36
GLY A  53
None
1.46A 2igtC-1s7hA:
undetectable
2igtC-1s7hA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1s7h YKOF
(Bacillus
subtilis)
4 / 5 PHE A  59
LEU A 187
VAL A 185
VAL A 170
None
1.14A 2m56A-1s7hA:
0.0
2m56A-1s7hA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)
1s7h YKOF
(Bacillus
subtilis)
5 / 9 LEU A  17
SER A  16
THR A  37
ALA A  61
THR A  35
None
1.27A 3mdtA-1s7hA:
undetectable
3mdtA-1s7hA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
1s7h YKOF
(Bacillus
subtilis)
4 / 6 VAL A 147
VAL A 137
PHE A 119
GLU A 155
None
1.50A 3n61A-1s7hA:
1.7
3n61B-1s7hA:
0.0
3n61A-1s7hA:
20.24
3n61B-1s7hA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
1s7h YKOF
(Bacillus
subtilis)
4 / 6 PHE A  59
LEU A 187
VAL A 185
VAL A 170
None
1.08A 3wrhE-1s7hA:
undetectable
3wrhE-1s7hA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
1s7h YKOF
(Bacillus
subtilis)
4 / 6 PHE A  59
LEU A 187
VAL A 185
VAL A 170
None
1.09A 3wrjE-1s7hA:
0.0
3wrjE-1s7hA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1s7h YKOF
(Bacillus
subtilis)
4 / 6 PHE A  59
LEU A 187
VAL A 185
VAL A 170
None
1.09A 4g3rA-1s7hA:
0.0
4g3rA-1s7hA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)
1s7h YKOF
(Bacillus
subtilis)
4 / 6 PHE A  59
LEU A 187
VAL A 185
VAL A 170
None
1.08A 4g3rB-1s7hA:
undetectable
4g3rB-1s7hA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)
1s7h YKOF
(Bacillus
subtilis)
3 / 3 VAL A 108
GLY A 110
LYS A 112
None
0.58A 4k50A-1s7hA:
undetectable
4k50A-1s7hA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)
1s7h YKOF
(Bacillus
subtilis)
3 / 3 VAL A 108
GLY A 110
LYS A 112
None
0.62A 4k50E-1s7hA:
undetectable
4k50E-1s7hA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)
1s7h YKOF
(Bacillus
subtilis)
3 / 3 VAL A 108
GLY A 110
LYS A 112
None
0.58A 4k50I-1s7hA:
undetectable
4k50I-1s7hA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)
1s7h YKOF
(Bacillus
subtilis)
4 / 6 PHE A  59
LEU A 187
VAL A 185
VAL A 170
None
1.16A 4kkyX-1s7hA:
undetectable
4kkyX-1s7hA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1s7h YKOF
(Bacillus
subtilis)
4 / 5 PHE A  59
LEU A 187
VAL A 185
VAL A 170
None
1.16A 4l49A-1s7hA:
0.0
4l49A-1s7hA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1s7h YKOF
(Bacillus
subtilis)
4 / 6 PHE A  59
LEU A 187
VAL A 185
VAL A 170
None
1.09A 4l4cA-1s7hA:
undetectable
4l4cA-1s7hA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
1s7h YKOF
(Bacillus
subtilis)
4 / 7 PHE A  59
LEU A 187
VAL A 185
VAL A 170
None
1.06A 4l4gA-1s7hA:
undetectable
4l4gA-1s7hA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)
1s7h YKOF
(Bacillus
subtilis)
4 / 5 ILE A 139
MET A 173
GLN A 176
ARG A 172
None
1.49A 5jm4A-1s7hA:
undetectable
5jm4A-1s7hA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)
1s7h YKOF
(Bacillus
subtilis)
4 / 8 ARG A  52
ALA A  11
THR A  81
GLY A  85
None
0.94A 5v0vA-1s7hA:
undetectable
5v0vA-1s7hA:
16.30