SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 1s7s H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, K-B ALPHA
CHAIN
(Mus
musculus) 		3 / 3 TRP A 167
GLU A  63
TYR A  59
 None
 1.03A 2a3aA-1s7sA:
undetectable		 2a3aA-1s7sA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 1s7s H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, K-B ALPHA
CHAIN
(Mus
musculus) 		5 / 12 ILE A 213
ASP A 212
THR A 214
VAL A 261
PRO A 185
 None
 1.24A 2yzqA-1s7sA:
undetectable		 2yzqA-1s7sA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1s7s H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, K-B ALPHA
CHAIN
(Mus
musculus) 		4 / 8 TYR A 123
TYR A  84
TYR A 118
HIS A  93
 None
 0.97A 2zm8A-1s7sA:
undetectable		 2zm8A-1s7sA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1s7s H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, K-B ALPHA
CHAIN
(Mus
musculus) 		4 / 8 TYR A 123
TYR A  84
TYR A 118
HIS A  93
 None
 1.03A 2zmaA-1s7sA:
undetectable		 2zmaA-1s7sA:
22.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 1s7s H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, K-B ALPHA
CHAIN
(Mus
musculus) 		5 / 10 ILE A  95
VAL A  97
TYR A 123
ILE A 124
TRP A 147
 None
 0.28A 3uprA-1s7sA:
34.1		 3uprA-1s7sA:
70.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 1s7s H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, K-B ALPHA
CHAIN
(Mus
musculus) 		5 / 10 ILE A  95
VAL A  97
TYR A 123
ILE A 124
TRP A 147
 None
 0.24A 3uprC-1s7sA:
34.2		 3uprC-1s7sA:
70.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 1s7s H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, K-B ALPHA
CHAIN
(Mus
musculus) 		5 / 12 ILE A  95
VAL A  97
TYR A 123
ILE A 124
TRP A 147
 None
 0.26A 3vrjA-1s7sA:
34.6
3vrjC-1s7sA:
undetectable		 3vrjA-1s7sA:
70.65
3vrjC-1s7sA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1s7s H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, K-B ALPHA
CHAIN
(Mus
musculus) 		4 / 8 TYR A 123
THR A  80
TYR A  85
ARG A  79
 None
 1.49A 3wipC-1s7sA:
undetectable
3wipD-1s7sA:
undetectable		 3wipC-1s7sA:
20.06
3wipD-1s7sA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 1s7s H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, K-B ALPHA
CHAIN
(Mus
musculus) 		5 / 12 ALA A 153
GLN A 114
VAL A  97
PHE A  74
ASN A  70
 None
 1.42A 4zj8A-1s7sA:
undetectable		 4zj8A-1s7sA:
19.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 1s7s H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, K-B ALPHA
CHAIN
(Mus
musculus) 		5 / 10 ILE A  95
VAL A  97
TYR A 123
ILE A 124
TRP A 147
 None
 0.25A 5u98A-1s7sA:
34.3		 5u98A-1s7sA:
70.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 1s7s H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, K-B ALPHA
CHAIN
(Mus
musculus) 		5 / 10 ILE A  95
VAL A  97
TYR A 123
ILE A 124
TRP A 147
 None
 0.26A 5u98D-1s7sA:
34.1		 5u98D-1s7sA:
70.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 1s7s H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, K-B ALPHA
CHAIN
(Mus
musculus) 		4 / 5 GLN A 242
THR A 233
THR A  31
GLY A 207
 None
 1.19A 6gbnC-1s7sA:
undetectable		 6gbnC-1s7sA:
20.35